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http://tripod.nih.gov/npc/

The NCGC Pharmaceutical Collection (NPC) is a comprehensive, publically-accessible collection of approved and investigational drugs for high-throughput screening that provides a valuable resource for both validating new models of disease and better understanding the molecular basis of disease pathology and intervention. The NPC has already generated several useful probes for studying a diverse cross section of biology, including novel targets and pathways. NCGC provides access to its set of approved drugs and bioactives through the Therapeutics for Rare and Neglected Diseases (TRND) program and as part of the compound collection for the Tox21 initiative, a collaborative effort for toxicity screening among several government agencies including the US Environmental Protection Agency (EPA), the National Toxicology Program (NTP), the US Food and Drugs Administration (FDA), and the NCGC. Of the nearly 2750 small molecular entities (MEs) that have been approved for clinical use by US (FDA), EU (EMA), Japanese (NHI), and Canadian (HC) authorities and that are amenable to HTS screening, we currently possess 2,400 as part of our screening collection. The NPC resource currently consists of (i) the physical collection suitable for high throughput screening (HTS) and (ii) the informatics browser and database. Putting together the physical collection has been surprisingly challenging in terms of the time and effort required in the informatics, compound management and synthetic chemistry related activities required for this endeavor. We provide access to the NPC screening library through collaboration. Please contact our Scientific Director Dr. Chris Austin for additional information. The other half of the NPC resource is the NPC browser. This is a self-contained software that is actively developed and maintained by the informatics group to provide electronic access to the NPC content. The latest version of the NPC browser for various platforms can be downloaded.

Proper citation: NCGC Pharmaceutical Collection (RRID:SCR_006909) Copy   

•   Source: SciCrunch Registry

http://tulane.edu/som/regenmed/services/index.cfm

The Stem Cell Research and Regenerative Medicine''s Tissue Culture Core provides cells for research use within the department, as well as for distribution to other facilities. The core obtains hMSCs from bone marrow donor samples and expands these cells for research use. The hMSC''s are also characterized for bone, fat and cartilage differentiation, and are stored on site for use. The Tissue Culture Core also handles the expansion and characterization of mouse and rat MSC''s. The animal cells are cultured in a separate area, and never interact with human derived cells. We also have a supply of hMSC''s marked with GFP+, Mito Red and Mito Blue available.

Proper citation: Tulane Stem Cell Research and Regenerative Medicine Tissue Culture Core (RRID:SCR_007342) Copy   

•   Source: SciCrunch Registry

http://nimhstemcells.org/

Induced Pluripotent Stem Cell (iPSC) and Source Cells available for distribution for postnatal-to-adult human control and patient-derived cells and their reprogrammed derivatives in support of stem cell research relevant to mental disorders. This includes but is not limited to anxiety disorders, attention deficit hyperactivity disorder, autism spectrum disorders, bipolar disorder, borderline personality disorder, depression, eating disorders, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, and schizophrenia. The capabilities of the repository range from derivation and banking of primary source cells from postnatal through adult human subject tissue to more comprehensive banking and validation of induced pluripotent stem cells (iPSCs) or similar reprogrammed / de-differentiated cells. Please send a message with the Contact page if you wish to contribute source cells or iPSC.

Proper citation: NIMH Stem Cell Center (RRID:SCR_006682) Copy   

•   Source: SciCrunch Registry

https://www.idigbio.org

iDigBio is the National Resource for Advancing Digitization of Biodiversity Collections (ADBC) funded by the National Science Foundation. Through ADBC, data and images for millions of biological specimens are being made available in electronic format for the research community, government agencies, students, educators, and the general public.

Proper citation: Integrated Digitized Biocollections (RRID:SCR_014336) Copy   

•   Source: SciCrunch Registry

https://www.beckman.com/flow-cytometry/instruments/moflo-astrios-eq

High speed flow cytometry sorter.

Proper citation: Beckman Coulter: Life Sciences MoFlo Astrios EQ Cell Sorter (RRID:SCR_018893) Copy   

•   Source: SciCrunch Registry

https://www.gmi-inc.com/product/beckman-j2-21m-high-speed-centrifuge/

Beckman J2-21M is a high speed floor model centrifuge which features a brushless induction drive and maintenance-free system. Capable of performing at a speed of 21,000 rpm and forces up to 51,500 g, the J2-21M offers superior functionality, accuracy, and productivity. The system's microprocessor-controlled design provides quick and automatic operation. The J2-21M Centrifuge stores up to 10 programs and eliminates errors in repetitive runs. The system also offers a choice of ten dual-ramp acceleration and deceleration settings for gentle starts and quick running.

Proper citation: Beckman Coulter: J2-21M/E Centrifuge (RRID:SCR_019669) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/wsrportal/techdocs?docname=cyan_adp_instructions_for_use.pdf

Flow cytometer engineered for precision analysis of cells, bacteria, and other similarly sized particles. CyAn ADP utilizes three excitation lines with independent, alignment-free focusing optics, simultaneous nine color and two scatter parameters, analysis rates of 70,000 events per second, a full 9 × 9 inter-laser compensation matrix, and high sensitivity. The instrument is optimized for cell cycle, kinetics, fluorescent protein work, and multi-color immunophenotyping. Rare-event analysis, such as MHC Dextramer studies, and no-lyse whole blood applications are easily performed on the CyAn ADP. The instrument also provides simplified compensation before, during, and after acquisition in all fluorescent parameters.

Proper citation: Beckman Coulter: CyAn ADP High-Speed Analyzer (RRID:SCR_019666) Copy   

•   Source: SciCrunch Registry

https://www.labx.com/product/beckman-166-detector

Variable wavelength UV/Vis HPLC detector with low noise and drift over a wide wavelength range.

Proper citation: Beckman Coulter: Model 166 UV detector (RRID:SCR_019675) Copy   

•   Source: SciCrunch Registry

https://www.beckman.com/flow-cytometry/instruments/gallios

Flow Cytometer provides efficient acquisition of up to 12 parameters to achieve accurate size measurement and high resolution and processing.

Proper citation: Beckman Coulter: Gallios Flow Cytometer (RRID:SCR_019639) Copy   

•   Source: SciCrunch Registry

https://scicrunch.org/browse/resourcesedit/SCR_018370

Immunoassay system analyzer by Beckman Coulter with standardized test menus, assay protocols, instrument processes and reference ranges. Sample types include serum, plasma, urine, amniotic fluid, and whole blood.

Proper citation: Beckman Coulter: UniCel DxI 800 Access Immunoassay System (RRID:SCR_020867) Copy   

•   Source: SciCrunch Registry

https://www.beckman.com/flow-cytometry/instruments/moflo-xdp

Cell sorter that combines high-speed sorting capability with an open flexible design to enable a wide variety of sorting applications.

Proper citation: Beckman Coulter: Moflo XDP (RRID:SCR_019648) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/urinalysis/iq200

iQ200 series automates sample microscopy and produces shortened TAT for low to high volume workloads.

Proper citation: Beckman Coulter: iQ200 Series Urinalysis Microscopy Instrument (RRID:SCR_019644) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/clinical-centrifugation/statspin-express-3

Primary tube centrifuge that can spin eight tubes up to 10mL and provides high quality plasma or serum in two to five minutes.

Proper citation: Beckman Coulter: StatSpin Express 3 Centrifuge (RRID:SCR_019657) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/clinical-centrifugation/statspin-express-2

Primary tube centrifuge that prepares high quality plasma or serum samples in two minutes.

Proper citation: Beckman Coulter: StatSpin Express 2 Centrifuge (RRID:SCR_019658) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/blood-banking/pk7300

Analyzer used for pre-transfusion, automated blood donor testing that features 300 sample per hour throughput, full online system status updates, data transfer capabilities, and aspiration and dispense monitoring intelligence.

Proper citation: Beckman Coulter: PK7300 Automated Microplate System (RRID:SCR_019653) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/clinical-centrifugation/statspin-cytofuge-2

Personal cytocentrifuge that provides high quality sample preparations with understandable controls and snap-seal filter concentrators.

Proper citation: Beckman Coulter: StatSpin Cytofuge 2 Cytocentrifuge (RRID:SCR_019656) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/blood-banking/pk7400

Analyzer that uses agglutination technology and a comprehensive blood-typing menu to deliver the highest throughput of blood donor immunohematology testing.

Proper citation: Beckman Coulter: PK7400 Automated Microplate System (RRID:SCR_019650) Copy   

•   Source: SciCrunch Registry

https://physiology.case.edu/media/eq_manuals/eq_manual_beckman_optima-l_series_instruction_manual_ll-im-12ab.pdf

Ultracentrifuge is used for centrifugation of subcellular particles, virus isolations, and high purity plasmid DNA.

Proper citation: Beckman Coulter: L-90K Ultracentrifuge (RRID:SCR_019651) Copy   

•   Source: SciCrunch Registry

https://www.beckman.com/liquid-handlers/biomek-4000

Beckman Coulter Biomek 4000 Automated Liquid Handler helps standardize daily pipetting routines, maintain sample quality and generate repeatable results.

Proper citation: Beckman Coulter: Biomek 4000 Automated Liquid Handler (RRID:SCR_019618) Copy   

•   Source: SciCrunch Registry

https://www.beckmancoulter.com/en/products/hematology/coulter-act-diff2

Hematology Analyzer delivers performance in open and closed analysis modes, wide operating range and multiple output formats.

Proper citation: Beckman Coulter: Coulter AcT diff2 Hematology Analyzer (RRID:SCR_019626) Copy   

•   Source: SciCrunch Registry