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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/NeLy-EPFL/LiftPose3D
Software tool for transforming 2D poses to 3D coordinates on labaratory animals. Used for kinematic studies of laboratory animals. Tracking movements in three dimensions from behaving flies, mice, rats, and non-human primates.
Proper citation: LiftPose3D (RRID:SCR_023049) Copy
https://rupertoverall.net/ColonyTrack/
Software R package to process raw data from ColonyRack system. In addition to generating pre processed data and quality control information, range of high level metrics are calculated together with convenient tools for analysis.
Proper citation: ColonyTrack (RRID:SCR_023026) Copy
https://github.com/vivian-imbriotis/rpg
Software Python package written for Raspberry Pi for displaying visual stimuli and to provide real time feedback on stimulus timing. High performance python library for displaying drifting gratings on Raspberry Pi 3.
Proper citation: Raspberry Pi Grating (RRID:SCR_023157) Copy
https://m3platform.weebly.com/
Software neuroscience laboratory environment for simultaneous neuronal imaging and behavioral monitoring. McGill-Mouse-Miniscope Touchscreen Behavior Platform. Standardized approach for high throughput imaging of neuronal dynamics during behavior.
Proper citation: M3 Platform (RRID:SCR_023425) Copy
https://github.com/KimchiLab/OpBoxPhys
Open source electrophysiology hardware and software package for simultaneous EEG and EMG acquisition from multiple subjects.
Proper citation: OpBox (RRID:SCR_023269) Copy
https://github.com/munoztd0/Mouthpiecegusto
3D printed pacifier shaped mouthpiece for fMRI compatible gustometers to deliver up to eight liquids during fMRI task. Can be utilized to study flavor, taste reactivity, reward or punishment with food, conditioning, and neurodegenerative conditions such as Alzheimers and Parkinsons, since taste and smell senses diminish early into disease acquisition.
Proper citation: 3DP Gustometer (RRID:SCR_025010) Copy
https://github.com/mmgxw3/pipetteFindingCNN
Software application for convolutional neural network that assesses pipette positioning before patch clamp is begun to minimize patch clamping errors in electrophysiology experiments. Used for detecting pipette positioning and making patch clamping procedures.
Proper citation: Pipette Finding CNN (RRID:SCR_024992) Copy
https://github.com/gchelini87/SEB3R
Software tool to automate and standardize ethologically driven observation of freely moving mice. Identifies different postures of mice and associates them with emotions, offering detailed analysis of their movements frame by frame. Used for tracking mouse body language and studying emotional behaviors.
Proper citation: SEB3R (RRID:SCR_025161) Copy
https://github.com/ZuAh/Custom-fitting-of-implants
Tutorial to custom-design and -fit implants to continuous and discontinuous skull surfaces. Universal Guide for Skull Extraction and Custom-Fitting of Implants to Continuous and Discontinuous Skulls.
Proper citation: Custom-fitting-of-implants (RRID:SCR_025270) Copy
https://github.com/mcmelo22/Licktech/tree/main
Lickometer system based on open-source hardware platform with user-friendly interface software, capable of simultaneously receiving data from eight automated cages with two drinking bottles each. Device to acquire high-quality and detailed data. Adaptable to new types of sensors or other neuroscience tools capable of measuring brain activity simultaneously to the behavior.
Proper citation: Lickometer Box (RRID:SCR_025248) Copy
https://github.com/jfrie/FARESHARE
Open source device for fluid tracking in socially housed rats. Device uses RFID and custom hardware to individually measure and record each rat's fluid consumption and licking microstructure.
Proper citation: FARESHARE (RRID:SCR_025330) Copy
https://github.com/LurLab-UCI/HERBs
Open source hardware and software solution for flexible implementation of complex behaviors in head-fixed mice. Low cost and requires little to no programming experience. Allows neural activity to be seen during testing, which will show relations between neuronal activity and behavior during tasks such as alternative forced choice, GoNoGo, and sensory stimulus presentation.
Proper citation: HERBs (RRID:SCR_025381) Copy
https://github.com/Aharoni-Lab/Ephys-Miniscope
Miniaturized calcium imaging microscope with integrated dense electrode technology for synchronous acquisition of neural activity across distant regions of the brain. Device based off open-sourced UCLA Miniscope to synchronously measure single cell activity at or near spike-time resolution across distant brain regions in freely behaving mice. Used to perform calcium imaging, with dense electrode electrophysiological recording, allowing simultaneous recordings from two remote brain regions in freely behaving mouse.
Proper citation: E-Scope (RRID:SCR_025396) Copy
https://github.com/MaSoMoTr/MaSoMoTr
Markerless video-based tool to simultaneously track two interacting mice of the same appearance in controlled settings for quantifying behaviors such as different types of sniffing, touching, and locomotion to improve tracking accuracy under these settings without increased human effort. It incorporates conventional handcrafted tracking and deep-learning-based techniques. The tool is trained on small number of manually annotated images from basic experimental setup and outputs body masks and coordinates of the snout and tail-base for each mouse.
Proper citation: Markerless Mouse Tracking for Social Experiments (RRID:SCR_025368) Copy
https://github.com/BerezhnoyD/Reaching_Task_VAI/
Open source hardware-software platform for analyzing reaching movement kinematics in mice. Used for studying fine motor skills in mice performing reach-to-grasp task. Behavioral platform uses readily available and 3D-printed components and was designed to be affordable and universally reproducible. Provides schematics, 3D models, code, and assembly instructions.
Proper citation: ReachOut (RRID:SCR_025502) Copy
https://github.com/Imbrosci/synaptic-vesicles-detection
Software tool as Python based synaptic vesicle classifier algorithm to identify neurotransmitter vesicles in electron microscopy images using Pytorch.
Proper citation: Synaptic Vesicles Detection (RRID:SCR_024910) Copy
https://github.com/asoronow/belljar/tree/main
Software mouse brain histology tool for neuroscientists. Semiautomated registration and cell counting tool for mouse neurohistology analysis.
Proper citation: Bell Jar (RRID:SCR_026912) Copy
https://www.eneuro.org/content/12/2/ENEURO.0444-24.2025
Low-cost implant for reliable diaphragm EMG recordings in awake, behaving rats.Diaphragm EMG implant.
Proper citation: Implant for Reliable Diaphragm EMG Recordings in Awake, Behaving Rats (RRID:SCR_026968) Copy
https://edspace.american.edu/openbehavior/project/ort/
Open-source apparatus to enable continuous individual monitoring, training, and testing of rats without removing them from their social environment. This system utilizes RFID technology to track individual animals, minimizing human intervention and providing precise behavioral data.
Proper citation: One-rat Turnstile (RRID:SCR_025570) Copy
https://github.com/3Dneuro/TD_Drive
Parametric, open-source implant for multi-area electrophysiological recordings in behaving and sleeping rats. 3D-printable implant for rats, capable of symmetric, bilateral wire electrode recordings, currently in up to six distributed brain areas simultaneously.
Proper citation: TD_Drive (RRID:SCR_025672) Copy
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