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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Provides methodology to evaluate activity and efficacy of new cancer therapeutics in solid tumors, using validated and consistent criteria to assess changes in tumor burden. RECIST Working Group comprises representatives of the European Organization for Research and Treatment of Cancer (EORTC), National Cancer Institute (NCI) of the United States and Canadian Cancer Trials Group (CCTG), as well as several pharmaceutical companies. Its mission is to ensures that RECIST undergoes continued testing, validation and updating.
Proper citation: Response Evaluation Criteria in Solid Tumors (RRID:SCR_026435) Copy
https://www.magstim.com/product/rapid%C2%B2/
Device to generate repetitive transcranial magnetic stimulation and is used in numerous fundamental and clinical research studies worldwide. Combines stimulation frequencies from 1Hz to 100Hz with touch screen interface which controls every aspect of stimulator’s control and operation.
Proper citation: Magstim: Rapid2 stimulator (RRID:SCR_026437) Copy
https://igit.informatik.htw-dresden.de/aagef650/spheroidsegdedeb
Software minimal tool for segmentation of irradiated tumor spheroids using optimized U-Net.
Proper citation: SpheroidSegDeDeb (RRID:SCR_026409) Copy
https://github.com/fzj-inm1-bda/siibra-python/
Software interface for interacting with brain atlases. Python client to brain atlas framework that integrates brain parcellations and reference spaces at different spatial scales, and connects them with broad range of multimodal regional data features. It aims to facilitate programmatic and reproducible incorporation of brain parcellations and brain region features from different sources into neuroscience workflows.
Proper citation: siibra-python (RRID:SCR_026596) Copy
https://www.renishaw.com/en/raman-software--9450
Renishaw windows-based Raman Environment, WiRE, software can control acquisition of Raman data and provide users with dedicated data processing and analysis options.
Proper citation: Renishaw WiRE software (RRID:SCR_026513) Copy
https://glkb.dcmb.med.umich.edu
Resource that integrates biomedical terms and biomedical relationships. This collection is curated from PubMed abstracts and biomedical repositories, offering unparalleled wealth of knowledge for researchers and practitioners in the field. The database is coupled with RESTful APIs and user-friendly web interface.
Proper citation: Genomic Literature Knowledge Base (RRID:SCR_026592) Copy
https://meyerinst.com/library/NanoZoomer_RS_Brochure_Catalog.pdf
High-resolution digital slide scanner designed for wide-field imaging of tissue samples. It captures high-quality digital images of microscope slides at up to 40x optical magnification. NanoZoomer XR scanner is capable of capturing images with a maximum resolution of 0.23 microns per pixel.
Proper citation: Hamamatsu: NanoZoomer-XR Digital slide scanner (RRID:SCR_026520) Copy
Multimode microplate reader with monochromator optics. Offers free wavelength selection and scanning capabilities. Used for all standard absorbance, fluorescence and luminescence assays.
Proper citation: Tecan: Infinite M Plex microplate reader (RRID:SCR_026522) Copy
https://discover-echo.com/revolve/
4-in-1 digital hybrid microscope, combining four microscopes into one. ECHO Revolve is a hybrid microscope that can be used for viewing glass slides and live samples in fluidic chambers. It can be used for upright or inverted observation methods.
Proper citation: ECHO: Revolve Microscope (RRID:SCR_026523) Copy
Time-of-Flight mass spectrometer for high-speed acquisition of highly multi-parametric single cell data. Simultaneously resolves multiple parameters with minimal signal overlap, providing insights into the functional and phenotypic complexity of biological systems at the single-cell level. Analyzes cells labeled with panel of reagents conjugated to stable metal isotopes using time-of-flight mass cytometry technology. Includes over 120 detection channels and 35 Maxpar metal probes.
Proper citation: Fluidigm: CyTOF 2 mass cytometer (RRID:SCR_026551) Copy
https://www.thermofisher.com/order/catalog/product/A44240
System supports the main imaging applications of chemiluminescent and colorimetric western blots, in addition to fluorescent stained nucleic acid gels, fluorescent stained protein gels, colorimetric stained protein gels, and colorimetric membrane stains.
Proper citation: Thermo Fisher: Invitrogen: iBright CL1500 Imaging System (RRID:SCR_026565) Copy
https://pmc.ncbi.nlm.nih.gov/articles/PMC10731520/
Cost-effective, compact foot-print, and open-source Raspberry Pi-based widefield imaging system. Used for close-proximity dual-brain cortical mesoscale functional-imaging to simultaneously observe activity in two head-fixed animals in staged social touch-like interaction. We provide all schematics, code, and protocols for a rail system where head-fixed mice are brought together to a distance where the macrovibrissae of each mouse make contact.
Proper citation: Meso-Py (RRID:SCR_026530) Copy
Ion trap mass spectrometer with electron transfer dissociation capabilities. Sets analytical standard for proteomics and small molecule applications.
Proper citation: Bruker: amaZon Speed ETD mass spectrometer (RRID:SCR_026526) Copy
https://www.bruker.com/en/products-and-solutions/mass-spectrometry/maldi-tof/rapiflex.html
Bruker MALDI-TOF mass spectrometry system. Enables time critical applications and faster decision making processes.
Proper citation: Bruker: rapifleX (RRID:SCR_026525) Copy
Triple Quadrupole Mass Spectrometer is liquid chromatograph mass spectrometer (LCMS) for fast, accurate detection, to quantify components of sample or to analyze their structure with increased specificity and sensitivity.
Proper citation: Shimadzu: LCMS-8060NX Triple Quad LC-MS/MS mass spectrometer (RRID:SCR_026527) Copy
Oven used to control the temperature of the column in a liquid chromatography LC system.CTO-40S Slim Line column oven is ideal for saving space while maintaining excellent thermal stability.
Proper citation: Shimadzu: Nexera HPLC/UHPLC Column Oven - CTO-40S (RRID:SCR_026529) Copy
The timsTOF SCP (single-cell proteomics) is mass spectrometer from Bruker. Ultra-high sensitivity instrument for quantitative single cell biology research with unbiased, deep single-cell 4D-Proteomics, immunopeptidomics, epiproteomics and PTM analysis. It features an additional separation in the tims cell where ions get separated according to their ion mobility, leading to collision cross-section values.Allows the analysis of hundreds of samples with minimal sample load (<200 ng) at sequencing speeds exceeding 100 Hz.
Proper citation: Bruker: timsTOF SCP mass spectrometer (RRID:SCR_026542) Copy
Spectrometer timsTOF Ultra 2 is paired with CaptiveSpray Ultra 2 ion source for high sensitivity to work with challenging samples and detect low-abundance peptides. Used to analyze even the smallest amounts and uncover previously unseen peptides.
Proper citation: Bruker: timsTOF Ultra 2 mass spectrometer (RRID:SCR_026541) Copy
Mass spectrometry (MS)-based proteomics instrument designed for shotgun proteomics and phosphoproteomics, leveraging Parallel Accumulation Serial Fragmentation (PASEF) technology to enhance speed, sensitivity, and resolution.
Proper citation: Bruker: timsTOF Pro mass spectrometer (RRID:SCR_026544) Copy
Mass spectrometer is equipped with the 4th generation high capacity TIMS-XR analyzer and advanced digitizer technology (ADT). Offers higher dynamic range for unmatched analytical depth and quantitation in high-throughput proteomics experiments.
Proper citation: Bruker: timsTOF HT mass spectrometer (RRID:SCR_026543) Copy
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