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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/2.12/bioc/html/BayesPeak.html
Software package that is an implementation of the BayesPeak algorithm for peak-calling in ChIP-seq data.
Proper citation: BayesPeak (RRID:SCR_013011) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/ChIPseqR.html
Software that identifies protein binding sites from ChIP-seq and nucleosome positioning experiments.
Proper citation: ChIPseqR (RRID:SCR_013016) Copy
http://www.bioconductor.org/packages//2.10/bioc/html/aCGH.html
Software functions for reading aCGH data from image analysis output files and clone information files, creation of aCGH S3 objects for storing these data. Basic methods for accessing/replacing, subsetting, printing and plotting aCGH objects.
Proper citation: aCGH (RRID:SCR_013232) Copy
http://www.bioconductor.org/packages/2.11/bioc/html/easyRNASeq.html
Software that calculates the coverage of high-throughput short-reads against a genome of reference and summarizes it per feature of interest (e.g. exon, gene, transcript). The data can be normalized as ''RPKM'' or by the ''DESeq'' or ''edgeR'' package.
Proper citation: easyRNASeq (RRID:SCR_012020) Copy
http://www.bioconductor.org/packages/release/bioc/html/LVSmiRNA.html
Software for normalization of Agilent miRNA arrays.
Proper citation: LVSmiRNA (RRID:SCR_012752) Copy
http://bioconductor.org/packages/release/bioc/html/MMDiff.html
Software package that detects statistically significant difference between read enrichment profiles in different ChIP-Seq samples.
Proper citation: MMDiff (RRID:SCR_012692) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/crlmm.html
Genotype Calling and Copy Number Analysis tool for Affymetrix SNP 5.0 and 6.0 and Illumina arrays.
Proper citation: CRLMM (RRID:SCR_012580) Copy
http://www.bioconductor.org/packages/release/bioc/html/baySeq.html
Software package that identifies differential expression in high-throughput ''count'' data, such as that derived from next-generation sequencing machines.
Proper citation: baySeq (RRID:SCR_012795) Copy
http://bioconductor.org/packages/devel/bioc/html/RPA.html
A fully scalable online pre-processing algorithm for short oligonucleotide microarray atlases.
Proper citation: RPA (RRID:SCR_012768) Copy
http://bioconductor.org/packages/release/bioc/html/lumi.html
Software that provides an integrated solution for the Illumina microarray data analysis.
Proper citation: lumi (RRID:SCR_012781) Copy
http://www.bioconductor.org/packages/release/bioc/html/rqubic.html
This software package implements the QUBIC algorithm for the qualitative biclustering with gene expression data.
Proper citation: rqubic (RRID:SCR_012869) Copy
Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance (SCCA) have merged to form Fred Hutchinson Cancer Center, unified adult cancer research and care center. Independent, nonprofit organization is clinically integrated part of UW Medicine and is UW Medicine’s cancer program.
Proper citation: Fred Hutchinson Cancer Center (RRID:SCR_004984) Copy
http://www.bioconductor.org/packages/release/bioc/html/iontree.html
Software package that provides utility functions to manage and analyse MS2/MS3 fragmentation data from ion trap mass spectrometry. It was designed for high throughput metabolomics data with many biological samples and a large numer of ion trees collected. Tests have been done with data from low-resolution mass spectrometry but could be readily extended to precursor ion based fragmentation data from high resoultion mass spectrometry.
Proper citation: iontree (RRID:SCR_002813) Copy
http://bioconductor.org/packages/2.1/bioc/html/arrayMagic.html
Software providing a collection of utilities for quality control and processing of two-colour cDNA microarray data
Proper citation: arrayMagic (RRID:SCR_010933) Copy
http://bioconductor.org/packages/epialleleR/
Software R package for calling hypermethylated variant epiallele frequencies at level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map files as input. Used for sensitive allele specific methylation analysis in next generation sequencing data. Used for sensitive detection, quantification and visualisation of mosaic epimutations in methylation sequencing data.
Proper citation: epialleleR (RRID:SCR_023913) Copy
https://scicrunch.org/resolver/SCR_002250
THIS RESOURCE IS NO LONGER IN SERVICE. Documented Jul 19, 2024. Metadatabase manually curated that provides web accessible tools related to genomics, transcriptomics, proteomics and metabolomics. Used as informative directory for multi-omic data analysis.
Proper citation: OMICtools (RRID:SCR_002250) Copy
http://www.bioconductor.org/packages/release/bioc/html/cn.farms.html
Software R package for copy number variation analysis that allows analysis of the most common Affymetrix (250K-SNP6.0) array types and supports high-performance computing using snow and ff.
Proper citation: cn.FARMS (RRID:SCR_000289) Copy
https://rdrr.io/bioc/spotSegmentation/
Model-based software package for processing microarray images so as to estimate foreground and background intensities. The method starts with a very simple but effective automatic gridding method, and then proceeds in two steps. The first step applies model-based clustering to the distribution of pixel intensities, using the Bayesian Information Criterion (BIC) to choose the number of groups up to a maximum of three. The second step is spatial, finding the large spatially connected components in each cluster of pixels. The method thus combines the strengths of the histogram-based and spatial approaches. It deals effectively with inner holes in spots and with artifacts. It also provides a formal inferential basis for deciding when the spot is blank, namely when the BIC favors one group over two or three.
Proper citation: spotSegmentation (RRID:SCR_001298) Copy
https://www.bioconductor.org/packages//2.7/bioc/html/plateCore.html
Software that provides basic S4 data structures and routines for analyzing plate based flow cytometry data.
Proper citation: plateCore (RRID:SCR_001743) Copy
https://bioconductor.org/packages/Orthology.eg.db/
Software R package to provide orthology mappings between species, based on NCBI Gene IDs and NCBI orthology mappings.
Proper citation: Orthology.eg.db (RRID:SCR_024740) Copy
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