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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/flowStats.html
Software using statistical methods and functionality to analyze flow data that is beyond the basic infrastructure provided by the flowCore package.
Proper citation: flowStats (RRID:SCR_000399) Copy
http://bioconductor.org/packages/2.12/bioc/html/Clonality.html
Software package for clonality testing providing statistical tests for clonality versus independence of tumors from the same patient based on their loss of heterozygosity (LOH) or genomewide copy number profiles.
Proper citation: Clonality (RRID:SCR_000293) Copy
http://www.bioconductor.org/packages/release/bioc/html/iBMQ.html
Software for integrated Bayesian Modeling of eQTL data. It implements a joint hierarchical Bayesian model where all genes and SNPs are modeled concurrently.
Proper citation: iBMQ (RRID:SCR_000481) Copy
http://www.bioconductor.org/packages/release/bioc/html/GeneExpressionSignature.html
An R package developed for the large-scale analysis of gene expression signatures. It gives the implementations of the gene expression signature and its distance to each. Gene expression signature is represented as a list of genes whose expression is correlated with a biological state of interest. And its distance is defined using a nonparametric, rank-based pattern-matching strategy based on the Kolmogorov-Smirnov statistic. Gene expression signature and its distance can be used to detect similarities among the signatures of drugs, diseases, and biological states of interest.
Proper citation: GeneExpressionSignature (RRID:SCR_000455) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowQ.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. Software that provides quality control and quality assessment tools for flow cytometry data.
Proper citation: flowQ (RRID:SCR_000575) Copy
http://www.bioconductor.org/packages/release/bioc/html/SigFuge.html
Algorithm for testing significance of clustering in RNA-seq data.
Proper citation: SigFuge (RRID:SCR_000444) Copy
http://www.bioconductor.org/packages/release/bioc/html/rqubic.html
This software package implements the QUBIC algorithm for the qualitative biclustering with gene expression data.
Proper citation: rqubic (RRID:SCR_012869) Copy
http://bioconductor.org/packages/release/bioc/html/DiffBind.html
Compute differentially bound sites from multiple ChIP-seq experiments using affinity (quantitative) data. Also enables occupancy (overlap) analysis and plotting functions.
Proper citation: DiffBind (RRID:SCR_012918) Copy
http://www.bioconductor.org/packages/release/bioc/html/iBBiG.html
A bi-clustering algorithm which is optimizes for binary data analysis.
Proper citation: iBBiG (RRID:SCR_012882) Copy
http://www.bioconductor.org/packages/release/bioc/html/eisa.html
A biclustering method; it finds correlated blocks (transcription modules) in gene expression (or other tabular) data.
Proper citation: eisa (RRID:SCR_012883) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/TurboNorm.html
Software providing a fast scatterplot smoother suitable for microarray normalization based on B-splines with second-order difference penalty. Functions for microarray normalization of single-colour data i.e. Affymetrix/Illumina and two-colour data supplied as marray MarrayRaw-objects or limma RGList-objects are available.
Proper citation: TurboNorm (RRID:SCR_012963) Copy
http://www.bioconductor.org/packages/release/bioc/html/methylumi.html
Software package that provides classes for holding and manipulating Illumina methylation data.
Proper citation: Methylumi (RRID:SCR_012831) Copy
http://www.bioconductor.org/packages/release/bioc/html/iChip.html
Software package that uses hidden Ising models to identify enriched genomic regions in ChIP-chip data.
Proper citation: iChip (RRID:SCR_012958) Copy
http://www.bioconductor.org/packages/release/bioc/html/NarrowPeaks.html
Software package for post-processing of peaks and differential binding in ChIP-seq based on standard wiggle visualization files. The double aim of the package is to apply a functional version of principal component analysis (FPCA) to: (1) Process data in wiggle track format (WIG) commonly produced by ChIP-seq peak finders by applying FPCA over a set of selected candidate enriched regions. This is done in order to shorten the genomic locations accounting for a given proportion of variation among the enrichment-score profiles. The function ''narrowpeaks'' allows the user to discriminate between binding regions in close proximity to each other and to narrow down the length of the putative transcription factor binding sites while preserving the information present in the variability of the dataset and capturing major sources of variation. (2) Analyze differential variation when multiple ChIP-seq samples need to compared. The function ''narrowpeaksDiff'' quantifies differences between the tag-enrichment, and uses non-parametric tests on the FPC scores for testing differences between conditions.
Proper citation: NarrowPeaks (RRID:SCR_012924) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/ChAMP.html
Software package that includes quality control metrics, a selection of normalization methods and novel methods to identify differentially methylated regions and to highlight copy number aberrations.
Proper citation: ChAMP (RRID:SCR_012891) Copy
http://bioconductor.org/packages/release/bioc/html/CSAR.html
Statistical tools for the analysis of ChIP-seq data.
Proper citation: CSAR (RRID:SCR_012930) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/CSSP.html
Software for power computation for ChIP-Seq data based on Bayesian estimation for local poisson counting process.
Proper citation: CSSP (RRID:SCR_012932) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/cghMCR.html
Software package that provides functions to identify genomic regions of interest based on segmented copy number data from multiple samples.
Proper citation: cghMCR (RRID:SCR_012898) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/RankProd.html
Software using a non-parametric method for identifying differentially expressed (up- or down- regulated) genes based on the estimated percentage of false predictions (pfp).
Proper citation: RankProd (RRID:SCR_013046) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/MEDIPS.html
Software developed for analyzing data derived from methylated DNA immunoprecipitation (MeDIP) experiments followed by sequencing (MeDIP-seq).
Proper citation: MEDIPS (RRID:SCR_012996) Copy
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