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Quality assessment software tool for evaluating and comparing genome assemblies. It works both with and without a given reference genome. It produces many reports, summary tables and plots.
Proper citation: QUAST (RRID:SCR_001228) Copy
http://www.bioconductor.org/packages/2.10/bioc/html/R453Plus1Toolbox.html
R software toolbox of functions for the analysis of data generated by Roche's 454 sequencing platform. Additional functions are included for quality assurance, annotation and visualization of detected variants, complementing the software tools shipped by Roche with their product. A pipeline for the detection of structural variants is provided.
Proper citation: R453Plus1Toolbox (RRID:SCR_001105) Copy
Commercial antibody supply company that focuses on providing antibodies for research in cardiovascular and atherosclerosis.
Proper citation: Academy Biomedical Company (RRID:SCR_001108) Copy
http://denverlab.science.oregonstate.edu/tileqc/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May,10, 2021.Software providing a visually oriented tile based approach to error detection for Solexa next-gen sequencing data. It is written in R and has both qualitative and quantitative error detection features. This software was written with the idea that the researcher's visual pattern recognition is the best way to detect novel errors and contains variety of ways to visualize that data. Once a new type of error is identified the data extraction features of the program may then be used as a starting point for the programmatic detection and/or filtration of similar errors. A supplementary role of tileQC is to convert the Eland and Q-score data contained within the Solexa "*_prb.txt" and "*_eland_results.txt" text files to a more flexible database form. Once in database form, tileQC simplifies the mechanics of interacting with that data and supplements standard SQL with an expression subsitution mechanism that allows R to be easily comingled with SQL. This system requires access to a mySQL server and the R package RMySQL as well as a few standard UNIX tools (also available on Windows and Macintosh).
Proper citation: TileQC (RRID:SCR_001229) Copy
http://www.criver.com/products-services/drug-discovery/capabilities/ion-channel/reagents
An ion channel focused Contract Research Organization (CRO) that does safety testing and screening for global pharma and biotech companies. ChanTest has developed a complete library of validated human ion channel-expressing cell lines to serve all the ion channel needs of its pharmaceutical and biotech customers. Services range from early functional screens for profiling drug candidates or ranking within profiles during the drug-discovery process to a complete set of in vitro GLP service products for cardiac risk assessment. ChanTest works in partnership with customers to speed the drug-development process, save time and money, and ultimately to help make better, safer drugs.
Proper citation: ChanTest (RRID:SCR_001220) Copy
http://bioinformatics.mdanderson.org/main/BreakFusion
Software package written in Perl and C++ that provides a computational pipeline for identifying gene fusions from RNA-seq data.
Proper citation: BreakFusion (RRID:SCR_001102) Copy
http://purl.bioontology.org/ontology/ICD11-BODYSYSTEM
Ontology of a set of body-system terms used in the ICD (International Classification of Diseases) 11 revision
Proper citation: Body System Terms from ICD11 (RRID:SCR_001252) Copy
http://www.bioconductor.org/packages/release/bioc/html/RCASPAR.html
Software package for survival time prediction based on a piecewise baseline hazard Cox regression model. It is meant to help predict survival times in the presence of high-dimensional explanatory covariates.
Proper citation: RCASPAR (RRID:SCR_001253) Copy
http://www.bioconductor.org/packages/release/bioc/html/CNVtools.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package to facilitate the testing of Copy Number Variant data for genetic association, typically in case-control studies.
Proper citation: CNVtools (RRID:SCR_001250) Copy
http://www.bioconductor.org/packages/release/bioc/html/CGEN.html
Software R package for analysis of case-control studies in genetic epidemiology.
Proper citation: CGEN (RRID:SCR_001251) Copy
https://omictools.com/npebseq-tool
A method for non-parametric, empirical Bayesian-based analysis of RNA-seq count data.
Proper citation: NPEBseq (RRID:SCR_001014) Copy
http://med.stanford.edu/tanglab/software/saber.html
Software program suitable for genome-scale data which uses a Markov-hidden Markov model (MHMM) to estimate local ancestry. The MHMM makes it possible to identify genomic blocks of a particular ancestry by use of any high-density single-nucleotide-polymorphism panel. One application is to perform admixture mapping without genotyping special ancestry-informative-marker panels.
Proper citation: SABER (RRID:SCR_001257) Copy
https://omictools.com/splitseek-tool
THIS RESOURCE IS NO LONGER IN SERVICE, documented September 20, 2016. A program for de novo prediction of splice junctions in RNA-seq data.
Proper citation: SplitSeek (RRID:SCR_001012) Copy
A commercial antibody supplier that specializes in high-quality monoclonal antibodies and antigens for the diagnostic industry.
Proper citation: Hytest (RRID:SCR_001133) Copy
http://www.stat.brown.edu/ZWU/research.aspx
Borrows information across sequences to establish prior distribution of sample variation, so that biological variation can be accounted for even when replicates are not available.
Proper citation: ASC (RRID:SCR_001013) Copy
Commercial antibody supplier and developer for biomedical research. These products are compatible with use in flow cytometry and mass cytometry, immunoprecipitation and chip, western blotting, immunofluorescence microscopy, and quantitative multiplexing.
Proper citation: BioLegend (RRID:SCR_001134) Copy
http://www.bioconductor.org/packages/release/bioc/html/multtest.html
Software package for non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.
Proper citation: multtest (RRID:SCR_001255) Copy
A C++ application designed for compression of genome collections from the same species.
Proper citation: GDC (RRID:SCR_001007) Copy
Commercial supplier which provides antibodies, assay kits, biomarkers, and proteins.
Proper citation: NewEast Biosciences (RRID:SCR_001129) Copy
http://www.softgenetics.com/mutationSurveyor.php
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software for DNA sequencing analysis that integates with Sanger Sequencing files generated by Applied Biosystems Genetic Analyzers, MegaBACE, and Beckman CEQ electrophoresis systems. It can be used to find single nucleotide polymorphisms (SNPs), insertions and deletions (INDELS), and somatic mutations in direct sequencing, PCR sequencing, mitochondrial DNA sequencing, and resequencing projects.
Proper citation: Mutation Surveyor (RRID:SCR_001247) Copy
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