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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.scienceexchange.com/facilities/am-biotechnologies-llc
AM Biotechnologies develops DNA-based affinity agents called thioaptamers using unique chemistries and a proprietary bead-based selection process. Antibodies are currently the most widely-used affinity agents but they are produced in animals; are easily degraded; are expensive to produce; and suffer from batch-to-batch variability. In contrast, thioaptamers are chemically synthesized; they are stable in ambient environments with very long shelf life; and are rapidly produced in large quantities with easy quality control. We solve the problems associated with antibodies while delivering the same functionality. Thioaptamers can be substituted for antibodies in virtually any application. We can develop thioaptamer affinity agents for your targets using our bead-based development service. AM also offers DNA thiophosphoramidite reagents via a strategic partnership with Glen Research Corporation and the RNA thiophosphoramidites are near market introduction. These unique reagents are used to synthesize thioaptamers and are also highly useful for providing in vivo stability and increased potency in RNAi applications. The company was founded in 2006 and is primarily owned by two corporations. It has been awarded numerous SBIR grants and has also benefited from over $10M of prior university research into its technologies. Importantly, all of our technologies have freedom to operate.
Proper citation: AM Biotechnologies (RRID:SCR_012568) Copy
http://www.scienceexchange.com/facilities/trevigen
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Trevigen Cell Assays (TCA), a division of Trevigen, Inc., was established in 2008 to conduct contract research work for the pharmaceutical, biotechnology, government and academic segments of the medical research market. TCA specializes in designing and conducting assays for lead compounds and genotoxic screening based on DNA damage and repair as well as cancer cell behavior.
Proper citation: Trevigen Cell Assays (RRID:SCR_012449) Copy
http://www.scienceexchange.com/facilities/university-of-nebraska-medical-center
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, core facility.
Proper citation: University of Nebraska Medical Center Labs and Facilities (RRID:SCR_012451) Copy
http://www.scienceexchange.com/facilities/harvard-neurodiscovery-center-harvard
Established in 2001 by Dr. Joseph Martin (Dean of Harvard Medical School, 1997-2007), the Harvard NeuroDiscovery Center is a pioneering biomedical research group focused on ending suffering from neurodegenerative diseases. By drawing on the intellectual strength and proven capability of the Harvard medical community and colleagues throughout the world, the NeuroDiscovery Center has developed a unique approach to understanding and treating these devastating diseases.
Proper citation: Harvard NeuroDiscovery Center Labs and Facilities (RRID:SCR_012695) Copy
http://www.scienceexchange.com/facilities/georgetown-university
An Portal, Core facility
Proper citation: Georgetown University Labs and Facilities (RRID:SCR_012694) Copy
http://www.scienceexchange.com/facilities/suny-at-stony-brook
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. Portal, Core facility
Proper citation: SUNY at Stony Brook Labs and Facilities (RRID:SCR_012455) Copy
http://www.scienceexchange.com/facilities/advanced-bioscience-laboratories
Advanced BioScience Laboratories, Inc (ABL) is a leading contract research and manufacturing organization, partnering with our clients to advance their vaccine and therapeutic development programs. Our unique combination of preclinical and clinical services provide the tools to address the scientific challenges encountered during any stage of product development. For preclinical studies, we utilize immunological, molecular, and cell-based assay platforms for candidate selection. We offer proof-of-concept in vivo studies with preclinical immunomonitoring and efficacy and potency testing. Once a clinical candidate is identified, ABL''s in-house cGMP suites are designed for single-use technologies accommodating a wide range of products, including mammalian- and microbial-based protein therapeutics as well as viral vectors and vaccines.
Proper citation: Advanced BioScience Laboratories (RRID:SCR_012576) Copy
http://www.scienceexchange.com/facilities/university-of-rochester
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility
Proper citation: University of Rochester Labs and Facilities (RRID:SCR_012454) Copy
http://www.scienceexchange.com/facilities/cornell-university
An Portal, Core facility
Proper citation: Cornell University Labs and Facilities (RRID:SCR_012457) Copy
https://www.tglabs.com/home.html
TG Labs Company, located in Colorado, has two divisions Technical division and Industrial division. Technical Division operates scientific, medical and chemical discovery laboratory in Englewood, Colorado. This division also develops special devices, equipment and processes for the medical, chemical and environmental industries. We offer proven solutions from concept through full scale production, including regulatory standards.
Proper citation: TG Labs (RRID:SCR_012581) Copy
http://www.scienceexchange.com/facilities/the-ohio-state-university
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Portal, Core facility
Proper citation: Ohio State University Labs and Facilities (RRID:SCR_012462) Copy
http://www.scienceexchange.com/facilities/ohio-university
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 14,2024. Portal, Core facility
Proper citation: Ohio University Labs and Facilities (RRID:SCR_012461) Copy
http://www.scienceexchange.com/facilities/german-cancer-research-center-dkfz
To perform research into cancer is the task of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ). DKFZ is the largest biomedical research institute in Germany and a member of the Helmholtz Association of National Research Centers. In over 70 divisions and research groups, our more than 2,500 employees, of which more than 1,000 are scientists, are investigating the mechanisms of cancer, are identifying cancer risk factors and are trying to find strategies to prevent people from getting cancer.They are developing novel approaches to make tumor diagnosis more precise and treatment of cancer patients more successful.
Proper citation: German Cancer Research Center Labs and Facilities (RRID:SCR_012708) Copy
http://www.rcsb.org/#Category-welcome
Collection of structural data of biological macromolecules. Database of information about 3D structures of large biological molecules, including proteins and nucleic acids. Users can perform queries on data and analyze and visualize results.
Proper citation: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) (RRID:SCR_012820) Copy
http://www.sourceforge.net/projects/matcont
MATCONT is a graphical MATLAB package for the interactive numerical study of parameterized dynamical systems. It is developed in parallel with the command line continuation toolbox CL_MATCONT and with the command line continuation toolbox CL_MATCONTM for the interactive numerical study of parameterized maps and iterates of maps. MATCONT and CL_MATCONT allow the numerical continuation of equilibria, limit cycles and homoclinic orbits, detection of codimension 1 and 2 bifurcations, continuation of the codimension 1 bifurcations and computation of their normal forms. For equilibria normal form coefficients of codimension 2 bifurcations are also computed, as well as switching to the codimension 1 curves in codimension 2 points. CL_MATCONTM provides similar facilities for maps and iterates of maps, including normal form coefficients of codimension 2 bifurcations and continuation of homoclinic and heteroclinic connections and tangencies of such connections.
Proper citation: MATCONT and CL MATCONT: Continuation Software in Matlab (RRID:SCR_012822) Copy
http://bioconductor.org/packages/release/bioc/html/DEXSeq.html
Software package focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.
Proper citation: DEXSeq (RRID:SCR_012823) Copy
http://www.urmc.rochester.edu/smd/nanat/home/index.cfm
The Department of Neurobiology and Anatomy is strongly committed to its major academic missions of research and education. Teaching and leadership roles in both graduate and medical education remain enduring commitments today, as they have been since the inception of the medical campus in the 1920s. This is matched by our commitment to research on the structure and function of the nervous system.
Proper citation: University of Rochester Medical Center Neurobiology and Anatomy (RRID:SCR_012705) Copy
Executive branch department of the federal government charged with coordinating and supervising all agencies and functions of the government directly related to national security and the United States Armed Forces.
Proper citation: U.S. Department of Defense (RRID:SCR_012712) Copy
Providing quality resources for the management of cerebral aneurysms and features an online calculator that calculates cerebral aneurysm volume and percent packing volume after coil embolization. The site also host an imaging Library with neuroanatomy and neurovascular images.
Proper citation: AngioCalc Cerebral Aneurysm Calculator (RRID:SCR_012805) Copy
http://umcd.humanconnectomeproject.org
Web-based repository and analysis site for connectivity matrices that have been derived from neuroimaging data including different imaging modalities, subject groups, and studies. Users can analyze connectivity matrices that have been shared publicly and upload their own matrices to share or analyze privately.
Proper citation: USC Multimodal Connectivity Database (RRID:SCR_012809) Copy
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