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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/AndreMacedo88/VEnCode
Software tool to perform intersectional genetics-related operations to find VEnCodes using databases provided by FANTOM5 consortium, namely CAGE enhancer and transcription start site (TSS) databases.
Proper citation: VEnCode (RRID:SCR_018024) Copy
https://www2.bri.nrc.ca/ccb/pub/sietraj_main.php
Software tool for binding free energies from Amber-generated MD trajectories. Alternative to MM-PBSA software provided by AMBER distribution. Virtual alanine mutations are also possible. Solvated interaction energies are calculated using parameters that have been fitted to reproduce binding free energies of data set of 99 protein-ligand complexes.
Proper citation: sietraj (RRID:SCR_018021) Copy
https://www.mbfbioscience.com/wormlab
Software tool for imaging, tracking, and analyzing C. elegans and other nematodes. It has user friendly software interface with patented model specific tracking algorithm that collects data about single worm or multiple worms, even through omega bends, coiling, reversals, and entanglements. Provides quantitative analysis of locomotory behavior with user configurable metrics for crawling and swimming assays.
Proper citation: Worm Lab (RRID:SCR_017669) Copy
Software package that autonomously diagnoses rare diseases from next generation sequencing NGS data using artificial intelligence by Diploid.
Proper citation: MOON (RRID:SCR_018005) Copy
https://www.mbfbioscience.com/help/vesselucida-explorer/Content/VesselucidaExplorer.html
Vesselucida Explorer is Vesselucida 360 companion analysis software, to perform analyses. Provides vasculature specific metrics such as segments and nodes counts, frequency of anastomoses, vessel surface and volume, and more.
Proper citation: Vesselucida Explorer (RRID:SCR_017674) Copy
http://apps.cytoscape.org/apps/cytohubba
Software tool for identifying hub objects and sub-networks from complex interactome. Predicts and explore nodes and subnetworks in given network by several topological algorithms. Provides interface to analyze topology of protein-protein interaction networks, such as human, yeast, rat, mouse, fly etc. Plugin works with Cytoscape 2.6 or above, which requires Java 1.5 or above.
Proper citation: cytoHubba (RRID:SCR_017677) Copy
Stimulator allows computer control of stimulus amplitude and timing parameters. Designed to speed up and enhance human peripheral nerve diagnostics by facilitating semi-automated nerve excitability tests. It also has roles in wider aspects of clinical neurophysiology research, including psychological, vestibular system and nociceptive testing. CE marked medical device under European Medical Device Regulation.
Proper citation: Digimeter: DS5 Isolated Bipolar Current Stimulator (RRID:SCR_018001) Copy
http://paintmychromosomes.com/
Software tool as algorithm for identifying population structure using dense sequencing data. Can perform model based Bayesian clustering on large datasets, including full resequencing data.
Proper citation: fineSTRUCTURE (RRID:SCR_018170) Copy
https://www.thermofisher.com/order/catalog/product/3730XL#/3730XL
96-capillary DNA analyzer that performs DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Has multiple automation features. Performs sequencing and fragment analysis applications including resequencing, microsatellite analysis, AFLP, LOH, SSCP, SNP screening and SNP validation.
Proper citation: Thermo Fisher: Applied Biosystems: 3730xl Capillary Genetic Sequencer (RRID:SCR_018059) Copy
https://servicesn.mbi.ucla.edu/SAVES/
Web server for structure validation in homology modeling. Used to validate of obtained crude models. Structure analysis and validation server.
Proper citation: SAVES (RRID:SCR_018219) Copy
https://github.com/lmcinnes/umap
Software package as dimension reduction technique that can be used for visualization similar to t-SNE, but also for general non-linear dimension reduction. Used for dimensionality reduction for visualizing single-cell data.
Proper citation: Umap (RRID:SCR_018217) Copy
https://github.com/yousra291987/ChiCMaxima
Pipeline for analyzing and identificantion of chromatin loops in CHi-C promoters data. Used to capture Hi-C visualization and interaction calling.
Proper citation: ChiCMaxima (RRID:SCR_018178) Copy
https://github.com/esctrionsit/snphub
Web Shiny-based server framework for retrieving, analyzing and visualizing large genomic variations data.
Proper citation: SnpHub (RRID:SCR_018177) Copy
https://github.com/BUStools/bustools/
Software tool for manipulating BUS files for single cell RNA-Seq datasets. Used to error correct barcodes, collapse UMIs, produce gene count or transcript compatibility count matrices, and is useful for many other tasks.
Proper citation: Bustools (RRID:SCR_018210) Copy
https://github.com/santeripuranen/SpydrPick
Software command line tool for performing direct coupling analysis of aligned categorical datasets. Used for analysis at scale of pan genomes of many bacteria. Incorporates correction for population structure, which adjusts for phylogenetic signal in data without requiring explicit phylogenetic tree.
Proper citation: SpydrPick (RRID:SCR_018176) Copy
https://github.com/santeripuranen/SuperDCA
Software tool for global direct coupling analysis of input genome alignments. Implements variant of pseudolikelihood maximization direct coupling analysis, with emphasis on optimizations that enable its use on genome scale. May be used to discover co evolving pairs of loci.Used for genome wide epistasis analysis.
Proper citation: SuperDCA (RRID:SCR_018175) Copy
https://www.bio-rad.com/en-us/product/cfx96-touch-real-time-pcr-detection-system?ID=LJB1YU15
Real Time PCR detection system that combines optical technology with temperature control. Six channel, five colors and one FRET channel, real-time PCR instrument for singlexplex or multiplex reactions. Quickly set up runs and monitor amplification traces in real time on integrated LCD touch screen, or use included CFX Maestro Software to design experiment and analyze results from connected computer.
Proper citation: Bio-Rad: CFX96 Real-Time PCR Detection System (RRID:SCR_018064) Copy
https://www.selectscience.net/products/zeiss-lsm-710-for-fluorescence-imaging/?prodID=84549#tab-2
Inverted microscope that enables confocal microscopy in cell and developmental biology.
Proper citation: Zeiss: LSM 710 Confocal Inverted Microscope (RRID:SCR_018063) Copy
https://satijalab.org/howmanycells
Web tool for calculating number of cells that must be sampled in order to see at least n cells of each type for single cell genomics experiments.
Proper citation: How many cells (RRID:SCR_018184) Copy
https://www.biocompare.com/Product-Reviews/41153-LSM-510-META-From-Zeiss/
Versatile laser scanning confocal microscope system that is available in both upright or inverted format. Equipped with ICS-Optics. Selection of dry, water immersion and oil immersion objectives are available. ICS-Optics are infinity color corrected.
Proper citation: Zeiss: LSM 510 Confocal Microscope (RRID:SCR_018062) Copy
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