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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://support.10xgenomics.com/de-novo-assembly/software/overview/latest/welcome
Software to generate phased, whole genome de novo assemblies from a Chromium prepared library. Used to create true diploid de novo assemblies and can separate homologous chromosomes over long distances.
Proper citation: Supernova assembler (RRID:SCR_016756) Copy
https://software.broadinstitute.org/software/discovar/blog/
Software tool for variant calling with reference and de novo assembly of genomes. The heart of DISCOVAR is a de novo genome assembler which can generate de novo assemblies for both large and small genomes.
Proper citation: Discovar assembler (RRID:SCR_016755) Copy
https://github.com/PathwayAnalysisPlatform/PathwayMatcher
Software tool for multi omics pathway mapping and proteoform network generation. Open source software writen in Java to search for pathways related to a list of proteins in Reactome.
Proper citation: PathwayMatcher (RRID:SCR_016759) Copy
https://github.com/BlaisProteomics/mzStudio
Software tool for proteomics data analysis, visualization, and notebook application. Dynamic digital canvas for user driven interrogation of mass spectrometry data. Operating system Unix/Linux, Windows.
Proper citation: mzStudio (RRID:SCR_017088) Copy
https://omictools.com/metacell-tool
Software package for single cell RNA-seq data analysis using k-NN graph partitions. Used to analyze group of scRNA profiles that are highly similar and provides features for deriving them. Can be used with large datasets., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Metacell (RRID:SCR_017013) Copy
https://omicssimla.sourceforge.io
Software tool for generating multi omics data with disease status. Simulates genomics (SNPs and copy number variations), epigenomics ( whole genome bisulphite sequencing), transcriptomics ( RNA seq), and proteomics (normalized reverse phase protein array) data at the whole genome level. Available as desktop and web application version.
Proper citation: OmicsSIMLA (RRID:SCR_017011) Copy
https://inutano.github.io/cwl-metrics/
Software framework to collect and analyze computational resource usage of workflow runs based on common workflow language CWL. Used to share set of tools packaged in containers. Enables users to choose proper cloud instance for workflow runs based on run time metrics data. Operating system Unix/Linux.
Proper citation: cwl-metrics (RRID:SCR_017076) Copy
https://github.com/dgrun/RaceID
Algorithm for identification of rare and abundant cell types from single cell transcriptome data. Based on transcript counts obtained with unique molecular identifies. Used for discovering rare cell types and corresponding marker genes in healthy and diseased organs. Operating system Unix/Linux, Mac OS, Windows.
Proper citation: RaceID (RRID:SCR_017045) Copy
http://www.cisreg.ca/cgi-bin/NHR-scan/nhr_scan.cgi
Web interface for computational prediction of nuclear hormone receptor binding sites in genomic sequences. Flexible Hidden Markov Model framework to allow for variable spacing and orientation of half sites. Allows for parameter modifications.
Proper citation: Nuclear Hormone Receptor Scan (RRID:SCR_016975) Copy
https://combine-lab.github.io/salmon/
Software tool for quantifying expression of transcripts using RNA-seq data. Provides fast and bias-aware quantification of transcript expression. Transcriptome-wide quantifier to correct for fragment GC-content bias.
Proper citation: Salmon (RRID:SCR_017036) Copy
https://github.com/fmaguire/Bridger_Assembler
Software package as de novo trascriptome assembler for RNA-Seq data. Framework for de novo transcriptome assembly using RNA-seq data. Can assemble all transcripts from short reads without using reference. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux.
Proper citation: Bridger (RRID:SCR_017039) Copy
https://pcago.bioinf.uni-jena.de/
Interactive web service for analysis of RNA-Seq read count data with principal component analysis (PCA) and agglomerative clustering. Includes features like read count normalization, filtering read counts by gene annotation and visualization options.
Proper citation: PCAGO (RRID:SCR_017033) Copy
https://github.com/jefferis/nat
Software R package for 3D visualisation and analysis of biological image data, especially tracings of single neurons.
Proper citation: NeuroAnatomy Toolbox (RRID:SCR_017248) Copy
https://bibiserv.cebitec.uni-bielefeld.de/pkiss
Software tool for folding RNA secondary structures, including two limited classes of pseudoknots. Performs abstract shape analysis for structures holding pseudoknots up to complexity of kissing hairpin motifs. Successor of pknotsRG. Used for secondary structure prediction including kissing hairpin motifs.
Proper citation: pKiss (RRID:SCR_017256) Copy
https://github.com/Barski-lab/cwl-airflow
Software Python package to extend Airflow functionality with Common Workflow Language support. Lightweight pipeline manager supporting Common Workflow Language. Can be used to run workflows on standalone MacOS/Linux servers, on clusters, or on cloud platforms.
Proper citation: CWL-Airflow (RRID:SCR_017196) Copy
https://www.beckman.it/flow-cytometry/research-flow-cytometers/cytoflex/software
Software program that controls instrument operation, data collection and analysis. Software for CytoFLEX Platform by Beckman Coulter.
Proper citation: CytExpert Software (RRID:SCR_017217) Copy
Software tool for efficiently solving large scale sequence matching tasks.
Proper citation: Vmatch (RRID:SCR_018968) Copy
https://github.com/Gaius-Augustus/BRAKER
Software tool as pipeline for accurate and automated gene prediction in novel eukaryotic genomes. Automated gene prediction training and gene prediction pipeline.BRAKER1 is eukaryotic genome annotation pipeline. BRAKER2 is extension of BRAKER1 which allows for fully automated training of gene prediction tools GeneMark EX R14, R15, R17, F1 and AUGUSTUS from RNA Seq and/or protein homology information, and that integrates extrinsic evidence from RNA-Seq and protein homology information into prediction.
Proper citation: BRAKER (RRID:SCR_018964) Copy
Software fast and lightweight tool for processing sequences in FASTA or FASTQ format.
Proper citation: Seqtk (RRID:SCR_018927) Copy
http://mips.helmholtz-muenchen.de/genre/proj/corum
Database of manually annotated protein complexes from mammalian organisms. Annotation includes protein complex function, localization, subunit composition, literature references and more. All information is obtained from individual experiments published in scientific articles, but data from high-throughput experiments is excluded.
The majority of protein complexes in CORUM originates from man (65%), followed by mouse (14%) and rat (14%)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CORUM (RRID:SCR_002254) Copy
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