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http://krasnow1.gmu.edu/cn3/index3.html

Multidisciplinary research team devoted to the study of basic neuroscience with a specific interest in the description and generation of dendritic morphology, and in its effect on neuronal electrophysiology. In the long term, they seek to create large-scale, anatomically plausible neural networks to model entire portions of a mammalian brain (such as a hippocampal slice, or a cortical column). Achievements by the CNG include the development of software for the quantitative analysis of dendritic morphology, the implementation of computational models to simulate neuronal structure, and the synthesis of anatomically accurate, large scale neuronal assemblies in virtual reality. Based on biologically plausible rules and biophysical determinants, they have designed stochastic models that can generate realistic virtual neurons. Quantitative morphological analysis indicates that virtual neurons are statistically compatible with the real data that the model parameters are measured from. Virtual neurons can be generated within an appropriate anatomical context if a system level description of the surrounding tissue is included in the model. In order to simulate anatomically realistic neural networks, axons must be grown as well as dendrites. They have developed a navigation strategy for virtual axons in a voxel substrate.

Proper citation: Computational Neuroanatomy Group (RRID:SCR_007150) Copy   

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http://student.biology.arizona.edu/honors2002/group09/home.html

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. HIV ...and its Coreceptors is a University of Arizona Biology 181 Honors Course describing HIV, its mechanisms of action, and more. Topics covered include: * What is HIV? The Human Immune System, How HIV attacks the Body, and How does HIV get into cells and infect them? * Interpreting and Understanding: CC CKR5: A RANTES, MIP-1a, MIP-1B Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1 * Interpreting and Understanding: Coreceptors: Implications for HIV Pathogenesis and Therapy * Statistics * Treatment: Nucleoside Reverse Transcriptase Inhibitors, Non-Nucleoside Reverse Transcriptase Inhibitors, Protease Inhibitors, Effects on Antiviral Therapy on Viral Burden * Present Research * Glossary * Links

Proper citation: HIV and its Coreceptors (RRID:SCR_007146) Copy   

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http://www.bbraunusa.com

Since 1839, B. Braun has delivered innovative healthcare products, services and educational programs that enhance the care and safety of patients and healthcare professionals in the fields of drug delivery, IV therapy, pain control, clinical nutrition, dialysis and vascular intervention. Their products and services are used in hospitals, outpatient surgery centers and in the home care setting. Keywords: Innovation, Healthcare, Product, Educational, Program, Hospital, Outpatient, Clinical, Nutrition, Dialysis, Vascular, Intervention,Surgery,

Proper citation: B Braun Sharing Expertise (RRID:SCR_007148) Copy   

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http://www.nybb.hs.columbia.edu/

A brain bank which collects postmortem human brains to meet the needs of neuroscientists investigating specific psychiatric and neurological disorders. NYBB disburses tissue samples to investigating clinicians or scientists whose research has been approved by their Institutional Review Board. The tasks of the NYBB include: collection and processing of human postmortem brain samples for research; neuropathological evaluation and diagnosis; storage and computerized inventory of brain samples; and distribution of brain samples to investigating clinicians and scientists. Brains from individuals without neurological or psychiatric disorders are used as normal controls.

Proper citation: New York Brain Bank at Columbia University (RRID:SCR_007142) Copy   

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http://pathology.duke.edu/files/neuroanat/nawr_index.html

Comprehensive neuroanatomy resource created for course PTA 201 Practical Neuroanatomy, including animated images and hyperlinked descriptions with the following major categories: Blood supply, motor systems, cranial nerves, neurohistology, functional organization, sensory systems, and major coverings.

Proper citation: Duke University NeuroAnatomy Web Resources (RRID:SCR_007145) Copy   

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http://bioinformatics.albany.edu/~dmaps

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. DMAPS database contains pre-computed multiple structure alignments for protein chains in the Protein Data Bank (PDB). Automated structure alignments have been generated for classified protein families using CE-MC algorithm. Alignments have been built only for those families with at least three members. Currently, multiple structure alignments are available for 3050 SCOP-, 3087 CATH-, 664 ENZYME- and 1707 CE-based families. Users will be able to retrieve multiple alignments for a given PDB chain classified by one of these criteria.

Proper citation: DMAPS - A Database of Multiple Alignments for Protein Structures (RRID:SCR_007140) Copy   

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http://wavis.img.cas.cz

WAViS generates pictures of your alignment files. These tools should help you with preparation of publication-quality pictures of your alignment. Sponsors: This resource is supported by Institute of Molecular Genetics. Keywords: Software, Server, Picture, Alignment,

Proper citation: WAViS: Alignment Visualization Tools Server (RRID:SCR_007213) Copy   

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http://www.alttox.org/

A website dedicated to advancing non-animal methods of toxicity testing, both to better protect the health of humans, animals, and the environment and to reduce the numbers and suffering of animals used in current toxicology assessments. The website is designed to encourage the exchange of technical and policy information on in vitro and in silico methods for all types of toxicity tests. The AltTox Forum is a message board for the AltTox community to use for posting news, information, and perspectives as well as encouraging feedback and commentary. This online community is intended to foster progress internationally in the development, validation, and acceptance of in vitro methods, with the goal of decreasing our reliance on animal-based safety testing. The Forum is moderated by a group of internationally-recognized subject matter experts. The Way Forward invited commentaries, which are posted in the TTRC, are opinion pieces written by experts in each relevant subfield. These essays are meant to help chart the course for future developments by advancing opportunities to overcome challenges and barriers to progress. Stakeholders are invited to comment on these essays in The AltTox Forum. AltTox users are encouraged to contribute to the website and interact with other users in several ways, including: :- Participating in the online forum :- Providing invited expert commentaries :- Suggesting or submitting content, events, monthly features, data, and graphics :- Providing feedback through the Website Feedback surve To encourage objectivity, the website content is overseen by an editorial board of distinguished subject matter experts.

Proper citation: AltTox: Non-animal Methods for Toxicity Testing (RRID:SCR_007212) Copy   

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http://www.frontiersin.org

Frontiers community is a web portal for both open access Frontiers journals and a community portal for jobs, books, and scholarly events. Frontiers is more than just an open-access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity of seeking, sharing and generating knowledge. As a first active measure in this direction, Frontiers provides immediate and permanent online open access to all of its publications, but this alone is not enough to realize our grand goals. The Frontiers solution develops around two main concepts, mutually integrating each other within the innovative Frontiers'' platform: * the Frontiers Journal Series, and * the Frontiers Community. As an open-access Journal Series, Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. As an interdisciplinary Community system, Frontiers is reshaping research management with a state-of-the-art platform, designed as a collaborative architecture and aimed at all research communities, whether academicians or research enthusiasts, investors or grantmakers. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new 21st century generation.

Proper citation: Frontiers Community: A Network that Serves researchers (RRID:SCR_007214) Copy   

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http://www.biomanta.org/

This project encompasses development of novel biological network analysis methods and infrastructure for querying biological data in a semantically-enabled format, and aims to create a semantic interactome model. Research within the BioMANTA project will focus on computational modelling and analysis, primarily using Semantic Web technologies and Machine Learning methods, of large-scale protein-protein interaction and compound activity networks across a wide variety of species. A range of information such as kinetic activity, tissue expression, and subcellular localization and disease state attributes will be included in the resulting data model. Protein interactions are a fundamental component of biological processes. Many proteins are functional only in multimeric complexes, or require interaction partners to achieve their correct localisation or function. For this reason, the study of protein-protein interaction (PPI) networks has become an area of growing interest in computational biology. Through the use of Semantic Web technologies such as Resource Description Framework (RDF) and Web Ontology Language (OWL), interaction data is modelled to create a knowledge representation in which meaning is vested in the ontology rather than instances of data. Stochastic and computational intelligence methods are applied to this data to infer high coverage networks. Semantic inferencing is used to infer previously unknown and meaningful pathways. Major project components: - The BioMANTA Ontology:- An OWL DL ontology incorporating the PSI-MI Ontology, the NCBI Taxonomy, and elements of BioPax ontology and Gene Ontology (describing subcellular localisation). This allows us to re-use existing ontologies, thereby reducing overheads associated with knowledge acquisition in the ontology development process. We are able to integrate existing public data that contain annotation in these formats. - Data conversion & semantic protein integration:- A set of software components that convert protein-protein databases (DIP, MPact, IntAct, etc.) from PSI-MI XML to RDF compliant with the BioMANTA ontology. These software allow us to make these protein-protein interaction datasets (and more generally, any PSI-MI XML data) semantically available for querying and inference within BioMANTA. - A RDF triple store based on RDF Molecules and the MapReduce architecture:- A proof-of-concept RDF triple store using RDF molecules and Hadoop scale-out architectures. Regular RDF graphs are deconstructed into RDF molecules, which are distributed over distributed compute nodes in the MapReduce architecture, and are subsequently combined to form equivalent RDF graphs. Such an approach makes the distributed SPARQL querying and reasoning on RDF triple stores possible. - A quantitative framework to integrate networks extracted from independent data sources (gene expression, subcellular localization, and ortholog mapping):- The model is multi-layer, with a first layer based on Decision Trees where each Decision tree is built on each dataset independently. The tree nodes are cut using Shannon''s entropy (mutual information); the decision of these independent trees is integrated using logistic regression, and the parameters are optimised using maximum likelihood. Sponsors: This resource is supported by the Pfizer Global Research and Development, the Institute for Molecular Bioscience (IMB), and the University of Queensland, Australia.

Proper citation: BioMANTA (RRID:SCR_007177) Copy   

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http://www.bioscreen.fi

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 18,2025. Biosceen C is a system designed for automating routine microbiology work. It uses a unique micro-plate format (10x10 wells), so called Honeycomb format, which is especially well suited for highly accurate temperature control. It features two covered honeycomb plates making it possible to run 200 samples simultaneously. Its unique patented incubator system features temperature control maintaining the set temperature with a 0,1 degree centigrade accuracy, while avoiding condensation of liquid on the inside of the micro plate lid. It can cool down the samples 6 degrees centigrade below the ambient temperature and its working range is from 1 to 60 degrees in steps of 0,1 degree centigrade. Sponsors: Oy Growth Curves Ab Ltd is a privately held company established in 2002 by a former Labsystems executive. It aquired the Bioscreen product line from Thermo Labsystems and has continued to maintain the product excellence Bioscreen is known for. Today the company is controlled by a new generation of owner operators, dedicated to continue developing Bioscreen to meet the demands of today''s users Keywords: Microbiology, Automation, Honeycomb, Incubation, System, Temperature, Technology, Supplier,

Proper citation: Bioscreen: C MBR (RRID:SCR_007172) Copy   

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http://noble.gs.washington.edu/

Our research group develops and applies computational techniques for modeling and understanding biological processes at the molecular level. Our research emphasizes the application of statistical and machine learning techniques, such as hidden Markov models and support vector machines. We apply these techniques to various types of biological data, including DNA and protein sequence data, as well as gene expression data from microarray experiments. We are currently developing methods for analyzing shotgun proteomics data, for characterizing protein function, structure and interactions, and for understanding the structure and regulatory influence of chromatin.

Proper citation: Noble Research Lab (RRID:SCR_007204) Copy   

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http://www.ch.embnet.org/software/BOX_form.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. This server takes a multiple-alignment file in either GCG''s MSF-format or Clustals ALN-format. Sponsors: This resource was supported by the Swiss EMBnet Node Server. Keywords: Server, Multiple-alignment,, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: BOXSHADE 3.21 (RRID:SCR_007165) Copy   

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http://www.lef.org/bloodtest

Blood testing is the single most important preventive tool you can use to help head off health problems. Life Extension makes it possible to take advantage of that tool at a fraction of the cost commercial blood labs charge. Get a picture of your overall health. Identify potential disease risks. Test for specific problems with comprehensive blood test panels and individualized tests like these: * Male and Female Comprehensive Panels * Cardiac Risk Factors * Vitamin Deficiencies * Hormone and Thyroid Panels * Metabolic and Chemistry Profiles

Proper citation: Life Extension: Laboratory and Blood Testing Services (RRID:SCR_007167) Copy   

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http://www.aspergillusflavus.org

This is a Research Community that is focused on reducing the threat of the Aspergillus flavus fungus and its toxin to human and animal health. Aspergillus flavus is a plant, animal, and human pathogen that produces the carcinogen, aflatoxin. An organized multidisciplinary team is coordinating research efforts to control this fungus and to prevent the formation of its toxin in food and feeds. Aspergillus flavus is a fungus. It grows by producing thread like branching filaments known as hyphae. Filamentous fungi such as A. flavus are sometimes called molds. A network of hyphae known as the mycelium secretes enzymes that break down complex food sources. The resulting small molecules are absorbed by the myceilium to fuel additional fungal growth. The unaided eye cannot see individual hyphae, but dense mats of mycelium with conidia (asexual spores) often can be seen. The ear of maize below shows the growth of the fungus covering four maize kernels. When young, the conidia of A. flavus appear yellow green in color. As the fungus ages the spores turn a darker green. Sponsors: This resource is supported by the Center for Integrated Fungal Research. Keywords: Aspergillus flavus, Research, Fungus, Toxin, Human, Animal, Health, Plant, Pathogen, Carcinogen, Aflatoxin, Food, Feed, Mold, Network, Enzyme,

Proper citation: Aspergillus Flavus and Aflatoxin (RRID:SCR_007200) Copy   

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http://www.researchals.org/

A research forum portal for ALS-related resources targeted specifically towards academic and industry-based researchers. The aim of the ALS Forum is to identify existing research resources and build new tools to help veteran researchers accelerate their work and to help those new to the ALS field quickly get up to speed. It currently consists of content developed through a partnership with the Alzforum and filtered for its relevance to ALS, as well as links to ALS review articles, and a dynamic listing of current drug development efforts relevant to ALS.

Proper citation: ALS Forum (RRID:SCR_007160) Copy   

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http://www.soros.org/openaccess/

The purpose of the Budapest Open Access Initiative was to accelerate progress in the international effort to make research articles in all academic fields freely available on the internet. The participants represented many points of view, many academic disciplines, and many nations, and had experience with many of the ongoing initiatives that make up the open access movement. In Budapest they explored how the separate initiatives could work together to achieve broader, deeper, and faster success. They explored the most effective and affordable strategies for serving the interests of research, researchers, and the institutions and societies that support research. Finally, they explored how OSI and other foundations could use their resources most productively to aid the transition to open access and to make open-access publishing economically self-sustaining. The result is the Budapest Open Access Initiative. It is at once a statement of principle, a statement of strategy, and a statement of commitment. The initiative has been signed by the Budapest participants and a growing number of individuals and organizations from around the world who represent researchers, universities, laboratories, libraries, foundations, journals, publishers, learned societies, and kindred open-access initiatives. We invite the signatures, support, and participation of the entire world scientific and scholarly community.

Proper citation: Budapest Open Access Initiative (RRID:SCR_007163) Copy   

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http://202.97.205.78/epidiff/QDMRTutorial.jsp

Software that provides a quantitative approach to quantify methylation difference and identify DMRs from genome-wide methylation profiles by adapting Shannon entropy.

Proper citation: QDMR (RRID:SCR_007162) Copy   

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http://www.cmc.ca/

CMC Microsystems enables and supports the creation and application of micro- and nano-system knowledge by providing a national infrastructure for excellence in research and a path to commercialization of related devices, components and systems. CMC Microsystems provides the tools, technologies and services that make microsystems research and development possible in universities across Canada. CMC delivers innovative and cost-effective services to a growing community of microsystems researchers that connect 43 universities and one college across Canada, and presently involves over 3,100 faculty and graduate students. A 4th Pillar organization stimulating synergistic collaboration among universities, companies and government agencies, CMC is a pioneer in developing creative solutions including Canada-wide Internet-based access to advanced microsystems testing facilities-at a fraction of the cost of conventional methods. Over the last five years, CMC delivered a value of 342 million to Canadian universities. Throughout the last 25 years CMC has successfully demonstrated the ability to specify, acquire and distribute all the necessary tools and technologies to design, make and test microsystems devices, components and systems and in the last five years has significantly expanded its skill base and partnerships. CMC has also developed a series of key relationships with suppliers which have enabled smooth and uninterrupted access to the latest tools and technologies. The governance structure is widely viewed as one of the soundest among organizations of this type and the management team of five people has a total experience of well over 100 years in the microsystems field.

Proper citation: Canadian Microelectronics Corporation Microsystems (RRID:SCR_007234) Copy   

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http://archives.niddk.nih.gov/patient/bach/bach.aspx

An epidemiologic study being conducted in the Boston metropolitan area to examine the prevalence of symptoms for health problems such as interstitial cystitis, urinary incontinence, benign prostatic hyperplasia, prostatitis, hypogonadism, and sexual function. Of interest to the survey are health disparities and inequalities. BACH is especially concerned with lack of adequate health insurance, lack of access to adequate medical care, and how these problems influence patterns of disease. The study also focuses on social determinants of disease that are over and above the contribution of individual characteristics and risk factors. To achieve a randomly sampled population, four neighborhoods were divided into 12 strata and from them investigators selected census blocks. Households were then randomly selected from the census blocks and sampled to identify eligible study participants. Investigators conduct a two-hour, in-home, bilingual field interview of all eligible participants, looking at symptoms and asking questions about lifestyle, physical activity, alcohol use, nutrition, demographics, and morbidity. They also conduct a detailed inventory of medications, both prescribed and over-the-counter, and take two non-fasting blood samples for hormone, cholesterol, and lipid levels that will be stored for future studies. By the time the study ends, approximately 6,000 men and women, ages 30 to 79, from four Boston area neighborhoods that have density levels proportionate with minority populations will have been interviewed in their homes. One third of the randomly sampled population will be African American; one third, Hispanic; and one third, Caucasian.

Proper citation: Boston Area Community Health Survey (RRID:SCR_007115) Copy   

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