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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A web-based publication of virtually all MIT course content for free. OCW is open and available to the world and is a permanent MIT activity. Materials include free lecture notes, exams, and videos from MIT. No registration required. MIT OpenCourseWare is a free publication of MIT course materials that reflects almost all the undergraduate and graduate subjects taught at MIT. * OCW is not an MIT education. * OCW does not grant degrees or certificates. * OCW does not provide access to MIT faculty. * Materials may not reflect entire content of the course. A site overview is available for MIT OpenCourseWare. You can also browse courses by department or use the advanced search to locate a specific course or topic. High school students and educators should check out Highlights for High School.
Proper citation: MIT OpenCourseWare (RRID:SCR_005555) Copy
http://www.gis.a-star.edu.sg/internet/site/
Proper citation: Genome Institute of Singapore; Singapore; Singapore (RRID:SCR_005556) Copy
http://code.google.com/p/ea-utils/
Command-line software tools for processing biological sequencing data. Barcode demultiplexing, adapter trimming, etc. Primarily written to support an Illumina based pipeline - but should work with any FASTQs.
Proper citation: ea-utils (RRID:SCR_005553) Copy
http://code.google.com/p/bseqc/
A quality control software package specially for bisulfite sequencing experiments. It can comprehensively evaluate the quality of BS-seq experiments and automatically trim nucleotides with potential technical biases. In addition, BSeQC also support removing duplicate reads and keeping one copy of the overlapping segment in paired-end sequencing.
Proper citation: BSeQC (RRID:SCR_005428) Copy
Public university based in the city of Liverpool, England. Founded as a college in 1881, it gained its Royal Charter in 1903 with the ability to award degrees and is also known to be one of the six original 'red brick' civic universities.
Proper citation: University of Liverpool; Liverpool; United Kingdom (RRID:SCR_005424) Copy
The International Agency for Research on Cancer (IARC) is part of the World Health Organization. IARC''s mission is to coordinate and conduct research on the causes of human cancer, the mechanisms of carcinogenesis, and to develop scientific strategies for cancer prevention and control. The Agency is involved in both epidemiological and laboratory research and disseminates scientific information through publications, meetings, courses, and fellowships.
Proper citation: International Agency for Research on Cancer (RRID:SCR_005422) Copy
The mission of AIDS.ORG is to help prevent HIV infections and to improve the lives of those affected by HIV and AIDS by providing education and facilitating the free and open exchange of knowledge at an easy-to-find centralized website. AIDS.ORG makes access to important AIDS information easier and faster. We provide prevention, testing, and treatment information currently to well over 4 million people a year. AIDS.ORG has been awarded the Health on the Net Foundation Code of Conduct (HONcode) seal for reliability and credibility of information in the field of healthcare. Additionally, every year over 2.4 million young people under the age of 25 turn to AIDS.ORG, making us an important resource since over 50% of all new HIV infections in the USA occur in this age group. AIDS.ORG, Inc. is a nonprofit 501(c) (3) educational organization, and maintains a very strict privacy policy. We make it our goal to be the best starting point for someone looking for AIDS information on the Internet. Our intent is that users be directed to the best information on the topic they''re investigating. We bring people together to share knowledge and experiences. In the past, we also provided the very first Internet-based program of accredited AIDS education for medical professionals, allowing doctors in rural and isolated areas to better serve AIDS patients.
Proper citation: AIDS.org (RRID:SCR_005537) Copy
http://cvcweb.ices.utexas.edu/cvcwp/?page_id=100
VolumeRover (a.k.a VolRover) is an interactive multi-purpose image processing software that can visualize three dimensional imaging data of any size (as big as terabyte) in a commodity PC or workstation and additionally supports the following image processing operations. Image Contrast Enhancement, Filtering/Noise Reduction, Image Segmentation, Isocontouring, Symmetry Detection (for Virus Maps, Boundary-free Image Skeletonization. VolRover provides a user interface to a number of CVC software packages including Segmentation, Contrast Enhancement, and Motif Elucidation.
Proper citation: VolumeRover (RRID:SCR_005457) Copy
http://brainarray.mbni.med.umich.edu/brainarray/ngsqc/
Software pipeline that provides a set of novel quality control measures for quickly detecting a wide variety of quality issues in deep sequencing data derived from two dimensional surfaces, regardless of the assay technology used. It also enables researchers to determine whether sequencing data related to their most interesting biological discoveries are caused by sequencing quality issues. NGSQC can help to ensure that biological conclusions, in particular those based on relatively rare sequences, are not caused by low quality sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: NGSQC (RRID:SCR_005459) Copy
http://www.nammfoundation.org/
The NAMM Foundation is a non-profit organization with the mission of advancing active participation in music making across the lifespan by supporting scientific research, philanthropic giving and public service programs from the international music products industry. FOUNDATION ACTIVITIES: * Research: The NAMM Foundation provides support for projects that explore the impact of active music making during various stages of life and on human experience and conditions. The Foundation then promotes this research through the media to educate people of all ages about the proven benefits of playing music. * Program Grants: The NAMM Foundation supports innovative community-based music learning programs that allow more people the opportunity to experience the proven benefits of active music making. In 2010, the NAMM Foundation provided close to $600,000 in grants to worthy organizations and programs. * Wanna Play Fund: Wanna Play? is a public education campaign designed by NAMM in 2006 to raise awareness of the many benefits of music making and inspire people of all ages and talent levels to become active music makers. Initiated in September 2009, the Foundation''s Wanna Play Fund seeks public donations for programs and activities that expand access to music education and participation in music making for people of all ages. Donations to the Wanna Play Fund will be used to provide musical instruments to schools that are expanding or re-instating music education programs. * The Museum of Making Music: The mission of the Museum of Making Music is to celebrate the rich history and encourage the future of music making. The one-of-a-kind museum invites all NAMM Members to tour the Museum FREE of charge. Located in the NAMM Industry Headquarters in beautiful Carlsbad, Calif., the museum is a great way to experience first-hand the impact of the music products industry over the last 100 years. For more information about the museum or its activities, call 877-551-9976 or visit www.museumofmakingmusic.org. * SupportMusic Coaltion and Music Education Advocacy: The NAMM Foundation seeks to strengthen music education in schools and communities nationwide through its SupportMusic Coalition and website. Music and the arts are vital to every child''s education. SupportMusic provides tools and resources to advance community support for music education with the idea that local parents, teachers, students and advocates CAN make a difference! The NAMM Foundation also annually releases a list of the ������??Best Communities for Music Education������?? honoring schools that demonstrate a strong commitment to music and arts as part of a well-rounded education for every child.
Proper citation: NAMM Foundation (RRID:SCR_005453) Copy
http://www.stat.purdue.edu/~cheng70/code.html
A classification software for DNA methylation profiling with bisulphite next-generation sequencing data.
Proper citation: MSC (RRID:SCR_005450) Copy
Institute in the field of immunology, experimental rheumatology and rheumatism epidemiology.
Proper citation: German Rheumatism Research Centre Berlin; Berlin; Germany (RRID:SCR_005451) Copy
http://smithlab.usc.edu/plone/software/mlml
A software tool to simultaneously estimate hydroxymethylation (5hmC) and methylation (5mC) levels from BS-seq, oxBS-seq and TAB-seq experiments. It generates consistent estimates across experiment types.
Proper citation: MLML (RRID:SCR_005449) Copy
http://bioinfo2.ugr.es/MethylExtract/
A user friendly software tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation.
Proper citation: MethylExtract (RRID:SCR_005446) Copy
Tool for identification and analysis of CpG methylation patterns of genomic regions from high-throughput bisulfite sequencing data. It may identify the unmethylated and methylated regions for a single sample, the conserved and differential methylation regions with different methylation patterns for paired or multiple samples. It includes four main modules as follows: # Normalization of the sequencing reads of cytosines following guanines; # Identification of the unmethylated (methylated) regions using hotspot extension algorithm; # Identification of conservatively and differentially methylated regionsby combining the combinatorial algorithm for determination of potentially functional regions with the algorithm of analysis of variance (ANOVA) for assess the statistical significance of differentially methylated regions; # Extraction of sequence features and visualization of these potentially functional regions.
Proper citation: CpG MPs (RRID:SCR_005441) Copy
http://campagnelab.org/software/gobyweb/
Web application that facilitates the management and analysis of high-throughput sequencing (HTS) data. In the back-end, it uses the Goby framework, BWA, STAR, Last, GSNAP, Samtools, VCF-tools, along with a cluster of servers to provide rapid alignment and efficient analyses. GobyWeb makes it possible to analyze hundreds of samples in consistent ways without having to use command line tools. GobyWeb provides tools that streamline frequent data analyses for RNA-Seq, Methyl-Seq, RRBS, or DNA-Seq datasets and to enable teams of investigators to share reads and results of analyses. GobyWeb can be extended for new analyses by developing plugins.
Proper citation: GobyWeb (RRID:SCR_005443) Copy
http://www.ncbi.nlm.nih.gov/gtr/
Central location for voluntary submission of genetic test information by providers including the test''s purpose, methodology, validity, evidence of the test''s usefulness, and laboratory contacts and credentials. GTR aims to advance the public health and research into the genetic basis of health and disease. GTR is accepting registration of clinical tests for Mendelian disorders, complex tests and arrays, and pharmacogenetic tests. These tests may include multiple methods and may include multiple major method categories such as biochemical, cytogenetic, and molecular tests. GTR is not currently accepting registration of tests for somatic disorders, research tests or direct-to-consumer tests.
Proper citation: Genetic Testing Registry (RRID:SCR_005565) Copy
http://www.computationalbioenergy.org/qc-chain.html
A software package of quality control tools for next generation sequencing (NGS) data, consisting of both raw reads quality evaluation and de novo contamination screening, which could identify all possible contamination sequences. This QC pipeline supplies a fast, easy-to-use, and parallel processing approach to accomplish the comprehensive QC steps, which could be applied widely to almost all kinds of NGS reads, including genomic, transcriptomic and metagenomic data.
Proper citation: QC-Chain (RRID:SCR_005438) Copy
http://bioimage.ucsb.edu/bisque
Open source database for exchange and exploration of biological images. Used to store, visualize, organize and analyze images in cloud. Centered around database of images and metadata.
Proper citation: Bisque database (RRID:SCR_005559) Copy
http://www.thehamner.org/technology-and-development/technology-transfer/index.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented on June 24, 2013. BMDExpress is a Java application used to analyze dose-response data from microarray experiments. The program was designed to perform a stepwise analysis on microarray data that combines bench mark dose (BMD) calculations with gene ontology (GO) classification analysis. The combination provides dose estimates at which different cellular processes are altered at a defined increase in risk based on expression levels in the untreated controls. The fitting of the data to the statistical models (linear, 2 polynomial models, 3 polynomial, and power models) is performed using source code borrowed from the U.S. Environmental Protection Agency''''s BMDS software. The MPPD model is a computational model that can be used for estimating human and rat airway particle dosimetry. The model is applicable to risk assessment, research, and education. The MPPD model calculates the deposition and clearance of monodisperse and polydisperse aerosols in the respiratory tracts of rats and human adults and children (deposition only) for particles ranging in size from ultrafine (0.01 m) to coarse (20 m). The models are based on single-path and multiple-path methods for tracking air flow and calculating aerosol deposition in the lung. The single-path method calculates deposition in a typical path per airway generation, while the multiple-path method calculates particle deposition in all airways of the lung and provides lobar-specific and airway-specific information. Within each airway, deposition is calculated using theoretically derived efficiencies for deposition by diffusion, sedimentation, and impaction within the airway or airway bifurcation. Filtration of aerosols by the head is determined using empirical efficiency functions. The MPPD model includes calculations of particle clearance in the lung following deposition. Eight tutorials are provided so that the user can learn to interact with the software.
Proper citation: The Hamner Institute for Health Sciences: BMDExpress and The multiple-path particle dosimetry (RRID:SCR_005511) Copy
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