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http://www.sylvester.org/BSSR

Provides biorepository resources, services and expertise in support of oncology research.Facilitates translational cancer research with standard operating procedures for patient consenting; protection of patient personal and clinical data; specimen procurement and processing; quality control of specimens; secured specimen storage, retrieval, and distribution; and provision of relevant de-identified clinical data. BSSR services include: biospecimen collection, annotation, processing, storage and distribution (including tissue, blood, and other fluids); plasma, serum, and peripheral blood mononuclear cell processing and cryopreservation; rapid acquisition of surgical tissue and fresh biopsies; participant screening and enrollment for biospecimen collection studies;formalin-fixed, paraffin embedded and frozen tissue retrieval, processing, sectioning, histological staining, and digital whole slide scanning; tissue microarrays production; support for non-therapeutic trials; consultation on project design, data analysis and interpretation. Offers access tobiobank of diverse tissue types, including clinically annotated neoplastic and non-neoplastic samples from diverse anatomical sites, and provides banked specimen as well as fresh specimen procurement at institution wide level.Through BSSR, investigators have access to specimens collected fromUniversity of Miami Hospital, Sylvester Comprehensive Cancer Center, Bascom Palmer Eye Institute, Jackson Memorial Hospital, as well as to specimens collected in more broadly based multi-site studies.

Proper citation: University of Miami Sylvester Comprehensive Cancer Center Biospecimen Shared Resource Core Facility (RRID:SCR_022889) Copy   

•   Source: SciCrunch Registry

https://cbc.arizona.edu/research/support-services/facilities/wm-keck-center-nano-scale-imaging

Interdisciplinary research facility in areas of imaging, nano-science and spectroscopy for measuring surface topography, surface properties, electrical measurements, fluorescence, sub-monolayer visible spectroscopy, and molecular structures.

Proper citation: University of Arizona W.M. Keck Center for Nano Scale Imaging Core Facility (RRID:SCR_022884) Copy   

•   Source: SciCrunch Registry

https://www.mdc-berlin.de/genomics

Facility comprises Next Generation Sequencing, Single Cell Technologies and Data Management teams. Offers professional project counseling, library preparation, and sequence production support for Max Delbruck Center for Molecular Medicine and Berlin Institute of Health at Charite institutes in Berlin.

Proper citation: MDC and BIH Technology Platform Genomics Core Facility (RRID:SCR_022782) Copy   

•   Source: SciCrunch Registry

https://voices.uchicago.edu/organoids/

The mission is to facilitate access, generation, banking, and usage of organoids and primary cells derived from patients and model organisms.

Proper citation: University of Chicago Organoid and Primary Culture Research Core Facility (RRID:SCR_022935) Copy   

•   Source: SciCrunch Registry

https://cri.uchicago.edu/bioinformatics/

Core offers services and expertise designed to allow BSD investigators to take full advantage of high throughput technologies.

Proper citation: University of Chicago Center for Research Informatics Bioinformatics Core Facility (RRID:SCR_022937) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/xd/research/research-cores/elemental-analysis/index.cfm

Provides highly sensitive elemental quantification, including sample preparation, data analysis, and experimental guidance, through Inductively Coupled Plasma Mass Spectrometry (ICP-MS) technology.

Proper citation: Oregon Health and Science University Elemental Analysis Core Facility (RRID:SCR_022746) Copy   

•   Source: SciCrunch Registry

https://aimi.psu.edu/

Connects industry members with Penn State research community of artificial intelligence and machine learning researchers and their students to solve real world problems and seize market opportunities.

Proper citation: Penn State University Center for Applications of Artificial Intelligence and Machine Learning to Industry Core Facility (RRID:SCR_022867) Copy   

•   Source: SciCrunch Registry

https://eicn.cnsi.ucla.edu/

Provides advanced electron imaging tools covering scale range from tens of micrometers to angstroms, and delivering valuable structural information for cell biology, microbiology, biomolecular, molecular, and materials sciences.Offers all major electron microscopy modalities.

Proper citation: University of California at Los Angeles California NanoSystems Institute Electron Imaging Center for Nanomachines Core Facility (RRID:SCR_022900) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/knight-cardiovascular-institute/center-radiochemistry-research

Provides access to tools for imaging with short lived radionuclides, data analysis and is integrated with campus centers SARIC and nuclear medicine clinic for quantitative imaging of these tracers in vivo that provides spatial and temporal data in order to improve our basic understanding of biochemical pathways, disease processes and help select personalized treatments that enhance clinical care. Highlights of our center include On-campus capacity to develop and produce radiopharmaceuticals to address specific research questions using in-vivo, real-time imaging;PET/CT, SPECT/CT (and soon PET/MRI) imaging capability to quantify organ perfusion, assess metabolic pathways, receptor function and density, and measure pharmacodynamics.Applications are directed toward range of models, ranging from small animals to non-human primates, to humans.

Proper citation: Oregon Health and Science University Center for Radiochemistry Research Core Facility (RRID:SCR_022745) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/biophysics-core

Core services including ensurance that purified proteins and other biomolecules of interest are uncompromised in terms of their structure and stability. Facilitates analyses of catalytic activities and functional interactions.Examines thermodynamic and kinetic parameters for association between proteins and small molecules.Facilitates hypothesis generation through coalescence of experimental data and computational modeling.Assists in setting up protein crystallization assays.

Proper citation: Oregon Health and Science University Biophysics Core Facility (RRID:SCR_022744) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/tissue-processing-laboratory/

Laboratory is located in Room 429 of the Levy Building.Services include tissue processing; H&E staining, trichrome, and other staining; creation of frozen sections; and deparaffinization. Provides cryostat for use by investigators within Penn Dental Medicine; cryostat training is available for a fee. Investigators requiring the services of the Tissue Processing Laboratory should contact the facility to arrange a meeting to set up the appropriate protocols. Special handling, specimen orientation, and any unique aspects of the tissue being processed will be discussed at that time; in some instances, it may be advantageous for the investigator to be present initially when the specimens are being oriented in the hot paraffin prior to the actual sectioning.

Proper citation: University of Pennsylvania School of Dental Medicine Tissue Processing Laboratory Core Facility (RRID:SCR_022863) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/xd/research/research-cores/bdp.cfm

Core provides designing studies and developing statistical analysis plans in clinical trials, clinical and community based intervention studies, laboratory experiments, and observational studies.Provides expertise in traditional and modern statistical methods.Can help with trial design and analysis, epidemiologic analysis, sample size and power, high dimensional data analysis, risk prediction, complex survey analysis, time-to-event and longitudinal models, and statistical simulation,data management and wrangling, analytic variable coding and data set creation, research database design, data visualization, manuscript preparation, statistical programming, and much more.

Proper citation: Oregon Health and Science University Biostatistics and Design Program Core Facility (RRID:SCR_022741) Copy   

•   Source: SciCrunch Registry

https://advancedimaging.vetmed.ucdavis.edu/

Fluorescence microscopy facility with two Leica confocal microscopes, one with superresolution capability,second with multi-photon imaging capability, and Zeiss Lightsheet microscope. Facility offers consultation, training, and support.

Proper citation: University of California at Davis Veterinary Medicine Advanced Imaging Core Facility (RRID:SCR_022862) Copy   

•   Source: SciCrunch Registry

https://ncdiabetesresearch.org/metabolomics

Provides platform for quantitative targeted metabolic profiling by MS/MS and GC/MS, supported by library of stable isotope labeled standards as well as extensive scientific expertise to help researchers navigate core resources and use of services.

Proper citation: North Carolina Diabetes Research Center Metabolomics Core Facility (RRID:SCR_022909) Copy   

•   Source: SciCrunch Registry

https://ncdiabetesresearch.org/genomics

Provides resources and expertise in genomics and mass spectrometry at Wake Forest Center for Precision Medicine. Provides unique access to instrumentation and analytical expertise to NCDRC faculty in support of advancement of diabetes research.Overlooks the use of existing resources at NCDRC partner institutions (UNC, NC A&T, and Duke University) to coordinate work and data analysis with Metabolomics Core to provide omics analyses.Offers analytic services, expertise, and tools to integrate data to better understand interactive systems at play in disease processes.

Proper citation: North Carolina Diabetes Research Center Genomics and Proteomics Core Facility (RRID:SCR_022907) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/diabetes-research-center/diabetes-research-center/drc-cores/tissue-procurement-and-processing

Core facilitates access and usage of tissues and services to meet specialized needs of diabetes research community to expedite and catalyze innovative diabetes research at UC AMC. Provides resources to assist DRC investigators with acquisition and processing of rodent and human tissue, and specialized cell lines that are broadly required for diabetes research.

Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Tissue Procurement and Processing Core Facility (RRID:SCR_022904) Copy   

•   Source: SciCrunch Registry

https://www2.uottawa.ca/research-innovation/animal-behaviour-core

Core provides access to state-of-the-art rodent behavioural testing equipment in facility optimized for behavioural testing. Provides expert assistance in project development, test design and execution, data analysis and interpretation, and novel test development.

Proper citation: University of Ottawa Behaviour and Physiology Core Facility (RRID:SCR_022882) Copy   

•   Source: SciCrunch Registry

http://www.dna.uga.edu/

Core laboratory for nucleic acid sequencing and bioinformatics. Mission includes research support, education, and training.Services encompass range of genomic techniques and applications, sequencing technologies, and bioinformatics analyses. GGBC operates multiple platforms for short-, long-, and single-molecule sequencing reads (i.e., Illumina MiSeq and NextSeq, PacBio Sequel, and Oxford Nanopore MinIon). We also write letters of support (LOS) to offer our capabilities and expertise for grant applications submitted to funding agencies.

Proper citation: University of Georgia Georgia Genomics and Bioinformatics Core Facility (RRID:SCR_022880) Copy   

•   Source: SciCrunch Registry

https://research.wayne.edu/proteomics

Protein identification and proteome analysis using Orbitrao Eclipse,Fusion and Q Exactive LC-MS/MS platforms. Affinity selection for phosphopeptides with analysis using HCD, CID and ETD. Validation and quantitation of proteins using MRM with a TSQ Vantage triple quad.

Proper citation: Wayne State University Proteomics Core Facility (RRID:SCR_022879) Copy   

•   Source: SciCrunch Registry

https://vivariumandtransgenicscore.vai.org/

Provides genetically modified animal models for our collaborators. For preexisting models provides rederivation or reconstitution for purpose of importing animals into Vivarium barrier. In the absence of preexisting models core works closely with partnering labs to generate their ideal mutation de novo, often using CRISPR technology. Usually beginning with a brief consultation, this process involves discussing factors such as ideal background strain, molecular methods for optimizing the intended genetic change, mutation induction strategies, screening approaches and eventual QC of the new mutant line with the overall goal of giving our collaborators a fully informed, realistic picture of their projects timeframe, pitfalls and workflow. Core provides mouse sperm and embryo cryopreservation services for purpose of archiving and distributing valuable lines. Institute is an AAALAC-accredited facility. All procedures are conducted according to the NIH Guide for the Care and Use of Laboratory Animals.

Proper citation: Van Andel Institute Transgenic Core Facility (RRID:SCR_022914) Copy   

•   Source: SciCrunch Registry