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https://sites.google.com/ucsc.edu/mal/

Operated by Institute of Marine Sciences with support from UCSC Division of Physical and Biological Sciences. Available to UCSC and University of California marine and coastal research community.Provides equipment including Shimadzu TOC-VCPH TC/TN analyzer,Dionex ICS-2000 Ion Chromatograph,UIC Carbon Coulometer Analyzer, Perkin-Elmer AAnalyst 100 Atomic Absorption Spectrophotometer, Thermo Genesys 10S UV-Visible Spectrophotometer, Turner Designs 10-AU Field Fluorometer, Turner Designs TD-700 Lab Fluorometer, Turner Designs TD-20/20 Luminometer,Lachat QuikChem 8000 Flow Injection Analyzer, Guildline 8410 PortaSal Salinometer, Labconco Freeze Dryer.

Proper citation: University of California at Santa Cruz Marine Analytical Laboratory Core Facility (RRID:SCR_022480) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/service/p/pathology/mass-spectrometry

Provides analytical resource focusing on application of mass spectrometry and allied chromatographies to analysis of small molecules, generally of less than 1,000 daltons molecular weight, in complex clinical and biological samples.

Proper citation: Cincinnati Children's Hospital Mass Spectrometry Core Facility (RRID:SCR_022638) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/small-animal-imaging/miti/index.html

Core provides intravital imaging equipment to acquire advanced descriptive and quantitative data for imaging studies. Includes Olympus FVMPE-RS advanced multiphoton microscope, multichannel, multiphoton excitation system specifically tailored for intravital and deep tissue imaging.System is additionally equipped with 458 and 588 nm stimulation laser lines for photobleaching, light stimulation and/or photoactivation of various fluorescent or caged constructs. Uses Spectra-Physics InSight X3 dual-line, tunable multiphoton laser for ultrafast, multichannel imaging.Available Neurotar Mobile Home Cage allows researchers to integrate real-time imaging with behavioral/locomotion tracking. Offers training and access to imaging system, support in design of experimental procedures, acquisition of image data, and analysis of acquired images.

Proper citation: University of Nebraska Medical Center Multiphoton Intravital and Tissue Imaging Core Facility (RRID:SCR_022478) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/service/c/clinical-trials/biobank

Provides access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research.

Proper citation: Cincinnati Children's Hospital Discover Together Biobank Core Facility (RRID:SCR_022632) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/imaging

Provides access to advanced analytical imaging and image post-processing methods for collaborators involved in basic and clinical research.

Proper citation: Cincinnati Children's Hospital Imaging Research Center Core Facility (RRID:SCR_022631) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/extracellular-vesicle-core

Provides comprehensive or selected services in necessary isolation, quantification and characterization of EVs. Isolation of EV is based on size exclusion using high-performance (SEC-HPLC) or gravity fed (e.g. iZon column) liquid chromatography, ultracentrifugation, and/or density gradient ultracentrifugation. Accurately characterizes EV particle size distribution and concentration using resistive pulse sensing techniques (nCS1, Spectradyne, LLC). Immunophenotype can be accomplished using nanoscale flow cytometry and/or chip array (ExoViewTM) techniques. Provides services in training and education for individuals and lab groups in all methods above and study design consultation.

Proper citation: University of Pennsylvania Penn Vet Extracellular Vesicle Core Facility (RRID:SCR_022444) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/cellular-imaging.html

Provides advanced light microscopy services for biomedical and translational research including workflow, training for independent work, assistance and technical support in microscopy techniques, quantitative image analysis. Offers training and support for imaging and analyzing gels and blots.

Proper citation: Fred Hutchinson Cancer Center Cellular Imaging Core Facility (RRID:SCR_022609) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/preclinical-imaging.html

Provides in vivo imaging technology and infrastructure to support basic and preclinical research. Offers diverse array of imaging modalities, including ultrasound and optical imaging, MRI, micro-CT and multiphoton microscopy.

Proper citation: Fred Hutchinson Cancer Center Preclinical Imaging Core Facility (RRID:SCR_022616) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/immune-monitoring.html

Supports investigators seeking evaluations of immunologic responses in basic and early stage clinical research settings. Provides resources and expertise to evaluate cellular immunologic processes and responses through reagents, molecular and cellular assays, assay development support and research consulting services.

Proper citation: Fred Hutchinson Cancer Center Immune Monitoring Core Facility (RRID:SCR_022615) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/flow-cytometry.html

Includes services from sterile cell sorting for therapeutic applications to whole cell mass spectrometry, diagnostics and early stage clinical trials. Provides expertise from experimental design to data analysis and troubleshooting, therapeutic cell sorting. Supports isolation of cells for Phase 1 clinical trials of cellular immunotherapies.

Proper citation: Fred Hutchinson Cancer Center Flow Cytometry Core Facility (RRID:SCR_022613) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/electron-microscopy.html

Offers techniques to resolve structures from cellular ultrastructure to molecular interactions. Offers expertise in EM sample preparation and imaging, cryogenic electron microscopy, technologies and services, training through complexities of electron microscopy workflow, from sample preparation to image processing. All users must be trained by core staff.

Proper citation: Fred Hutchinson Cancer Center Electron Microscopy Core Facility (RRID:SCR_022611) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/preclinical-modeling-core-lab.html

Supports development and maintenance of preclinical mouse models, including patient derived xenografts, cell line xenografts and genetically engineered mouse models.

Proper citation: Fred Hutchinson Cancer Center Preclinical Modeling Core Facility (RRID:SCR_022617) Copy   

•   Source: SciCrunch Registry

https://www.bcchr.ca/flowcore

Core provides equipment for flow cytometric analysis, full service cell sorting, training, and dissemination.

Proper citation: British Columbia Children's Hospital Research Institute Flow Cytometry Core Facility (RRID:SCR_022790) Copy   

•   Source: SciCrunch Registry

https://asrc.gc.cuny.edu/neuroscience/facilities/live-imaging-bioenergetics-facility/

Provides Zeiss LSM880 upright two photon confocal microscope with Airyscan, FAST model and CLARITY lens; LSM880 inverted live cell imaging confocal microscope with Airyscan and FAST model; Agilent Seahorse XFe24 live cell metabolic analyzer.Supported applications include in vivo imaging of live animals, time lapse live cell imaging with high resolution optical sectioning, deep imaging of fixed CLARITY tissues, calcium imaging, photo switching and photo uncaging, Fluorescence Recovery After Photobleaching, Forster Resonance Energy Transfer, laser ablation, and measuring mitochondrial respiration and glycolysis in live cells in real time.Provides advanced imaging analysis software Imaris for data processing.

Proper citation: City University of New York Advanced Science Research Center Live Imaging and Bioenergetics Core Facility (RRID:SCR_022945) Copy   

•   Source: SciCrunch Registry

http://www.hiim.unizg.hr/index.php/institut/glowlab

Multimodal preclinical in vivo imaging facility for small laboratory animals such as mice and rats. Expertise is in brain research, however it is possible to provide imaging services on any part of or on animal.Instruments include magnetic resonance imager (Bruker BioSpec 70/20 USR) and optical bioluminescence/fluorescence imager (Perkin Elmer IVIS Spectrum), fully equipped with anesthesia delivery and physiological monitoring/control system.Imaging unit is complemented by cell culture laboratory and small animal surgery room, allowing to set up and perform entire experimental protocols as needed. Provides longitudinal imaging services owing to animal housing unit within same space, equipped with individually ventilated cages for both rats and mice (Tecniplast Green line and Emmerald line). Home cage monitoring is also possible for mice as an additional service with our Tecniplast DVC cages.

Proper citation: University of Zagreb School of Medicine Laboratory for Regenerative Neuroscience Core Facility (RRID:SCR_022701) Copy   

•   Source: SciCrunch Registry

https://alms.cnsi.ucla.edu/become-a-user/

Offers microscopy services, consultation, and support for application of novel microscopic and spectroscopic methods and advanced image analysis techniques for study of macromolecules, cellular dynamics and nano-scale characterization of bio-materials. Provides collection of customized biological fluorescence microscopes and small-animal imaging devices to study biological processes with high spatial and temporal resolution in whole organisms and in living cells down to single molecule detection level with nanometer accuracy. Located in basement and second floor of CNSI building, two optical suites designed to house microscopes with the required environment control (low vibration, air-filtered, air-conditioned and light-tight) and services. Services include Wide-field Fluorescence Imaging Microscopy (on a limited basis), Confocal One-Photon and Two-Photon Laser Scanning Microscopy, (both point scanning and spinning disk), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), microscopic and macroscopic Fluorescence Lifetime Imaging (FLIM) with Time-Correlated-Single-Photon-Counting (TCSPC) and Near-Infrared (NIR) Detection, Stimulated Emission Depletion laser-scanning microscopy (STED) (a super-resolution technique), both microscopic and macroscopic (small animal) spectral unmixing and laser capture microdissection.

Proper citation: University of California at Los Angeles California NanoSystems Institute Advanced Light Microscopy and Spectroscopy Core Facility (RRID:SCR_022789) Copy   

•   Source: SciCrunch Registry

https://isotope.ucsc.edu/

Provides light stable isotope ratio analysis services to scientists from UCSC and from around the world.

Proper citation: University of California at Santa Cruz Stable Isotope Laboratory Core Facility (RRID:SCR_022947) Copy   

•   Source: SciCrunch Registry

https://flowcytometrycore.vai.org/

Core provides cell analysis and sorting services. Instruments include Cytek Aurora, Beckman Coulter CytoFLEX S, Thermo Fisher Attune CytPix, SONY MA900, and BD FACSSymphony S6.

Proper citation: Van Andel Institute Flow Cytometry Core Facility (RRID:SCR_022685) Copy   

•   Source: SciCrunch Registry

https://drexel.edu/core-facilities/facilities/material-characterization/

Facility provides technical expertise and instrumentation including nanoscience and engineering, polymer research, biomedical engineering, and chemistry and physics of solid materials.Houses electron microscopes, X-ray diffractometers, X-ray photoelectron spectrometer and suite of sample preparation tools. Staff members provide expert consultation, training and assistance to MCC users. Core is involved in teaching both undergraduate and graduate level courses in Materials Science and Engineering, Mechanical Engineering and Mechanics, Biomedical Engineering, and Biology. Trained and certified users are welcome to work independently on our instruments.

Proper citation: Drexel University Materials Characterization Core Facility (RRID:SCR_022684) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/physiology/research/echo-facility.html

Preclinical ultrasound imaging. Provided instruments include Vevo 3100, Vevo 3100 LAZR-X, Perkin Elmer Vega.

Proper citation: University of Nebraska Medical Center Echocardiography Imaging Core Facility (RRID:SCR_022683) Copy   

•   Source: SciCrunch Registry