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https://www.vet.upenn.edu/research/centers-laboratories/center/center-for-host-microbial-interactions

Offers consultation and laboratory services for high-throughput sequencing (HTS) experiments, with particular expertise and interest in microbiome/metagenome and RNA-seq applications. Provides instrumentation, including Illumina NextSeq 2000 and single cell platforms from 10X genomics and 1CellBio. Offers full service options, as well as hands on instruction for trainees who want to learn best practices for wet lab aspects of genomics experiments. Offers consultation services for all phases of HTS studies, from study design to bioinformatics analysis.

Proper citation: University of Pennsylvania Penn Vet Center for Host Microbial Interactions Core Facility (RRID:SCR_022434) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/r/rips/research/pharmacy

Our Investigational Pharmacy team is responsible for dispensing both inpatient and outpatient investigational medication for industry-sponsored, grant-funded and investigator-initiated protocols. We provide pharmacy services customized to each research protocol conducted at Cincinnati Children�s.

Proper citation: Cincinnati Children's Hospital Investigational Pharmacy Core Facility (RRID:SCR_022650) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/meg

Core facilitates study of normal and pathologic brain processes using magnetoencephalography.The purpose of the core is to make magnetoencephalography available to researchers across the institute.

Proper citation: Cincinnati Children's Hospital Magnetoencephalography Core Facility (RRID:SCR_022648) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dev-biology/core

Offers comprehensive CRISPR services to generate gene edited rodents and cells, and helps generate transgenic and chimeric mice via our microinjection service, cryopreserving unique mouse lines, and recovering them from liquid nitrogen storage via IVF and embryo transfer services.

Proper citation: Cincinnati Children's Hospital Transgenic Animal and Genome Editing Core Facility (RRID:SCR_022642) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.themiamiproject.org/research-resources/core-facilities/drug-discovery-core/

Core at Miami Project to Cure Paralysis leverages PerkinElmer Opera Phenix Plus high content screening system to provide assay development and phenotypic screening. Facility is also equipped with PerkinElmer Janus G3 liquid handler, featuring modular and variable dispense heads, to automate screening workflows and enhance throughput. Core supports phenotypic and target-based assays. Phenotypic assays range from 2D to 3D, widefield to confocal, and antibody to dye based. It collaborates with users to develop customized assays and analytical pipelines tailored to their specific needs. Current specializations include neurite tracing, lipid droplet quantification, cell viability, morphological and kinetic analyses, phagocytosis, cell marker detection, cell adhesion, among others.

Proper citation: Drug Discovery Core Facility (RRID:SCR_022542) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/fmch/mixed-methods-research-lab

Fosters the use of qualitative and mixed methods research methodologies with focus on integrating key stakeholder perspectives and goals into research designs. Collaborates with investigators to address timely, pressing questions across diverse disciplines and works with investigators to provide conceptual as well as technical support for broad research programs, including clinical, community based, and implementation science research questions.

Proper citation: University of Pennsylvania Perelman School of Medicine Mixed Methods Research Lab Core Facility (RRID:SCR_022418) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-microbial-culture-and-metabolomics-core

Provides equipment for aerobic and anaerobic culture of microbial species in both batch and continuous systems, as well as targeted metabolomic services of amino, bile, and short chain fatty acids. Offers training and usage for culture equipment; consultation regarding experimental design, and; anaerobic culture services. Examples of culture studies include isolation of microbial taxa from mammalian samples; interrogation of the physiology of microbial strains under different conditions (e.g., anaerobic/microaerobic/aerobic, differing nutrient limitations) using isolated strains or strains obtained from culture collections (another service offered by the core); co-culturing of defined microbial consortia to investigate microbe-microbe interactions, and; preparation of microbial products (live bacteria, heat-killed bacteria, bacterial supernatants) from single or defined-mixed microbial cultures for use in mammalian cell culture and/or animal model systems.

Proper citation: University of Pennsylvania Perelman School of Medicine Microbial Culture and Metabolomics Core Facility (RRID:SCR_022417) Copy   

•   Source: SciCrunch Registry

http://agl.tamu.edu/

Assists graduate students, staff and faculty launch, economize and expedite their research, especially when it involves DNA extraction and quality checks, targeted genotyping and DNA content analysis. Facilitates usage of complementary cores and assists with research planning and data analysis.AGL members have free lab access and reduced costs for services as well as one-on-one training and advising with AGL staff.

Proper citation: Texas A and M University AgriGenomics Laboratory Core Facility (RRID:SCR_022533) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/transcriptional-regulation-expression-facility-trex

Facility offers genomics profiling services including RNAseq, small RNA sequencing, and ATACseq.

Proper citation: Cornell University Biotechnology Resource Center Transcriptional Regulation and Expression Core Facility (RRID:SCR_022532) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/single-cell-genomics

Core to perform expression level analysis of thousands of genes in parallel.Uses RNA-Seq assays from Tecan Genomics, Takara and Illumina for samples with limited amounts of starting RNA. Microarray technology utilizing the Affymetrix GeneChip platform is also available.

Proper citation: Cincinnati Children's Hospital Single Cell Genomics Core Facility (RRID:SCR_022653) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/cardio-imaging

Offers imaging techniques using imaging and measurement tools. Offers consulting services ranging from educational seminars to assistance with grant and industry funding support.

Proper citation: Cincinnati Children's Hospital Cardiovascular Imaging Core Facility (RRID:SCR_022626) Copy   

•   Source: SciCrunch Registry

http://www.sylvester.org/OGSR

Provides access to technologies and services for study of genomics and epigenomics of cancer, in addition to providing technical expertise for project design, trouble shooting and pre and post award support. Services include next generation sequencing, single cell genomics, spatial genomics, gene expression assays and molecular quantitation, services for sample extraction and QC.

Proper citation: University of Miami Sylvester Onco Genomics Shared Resource Core Facility (RRID:SCR_022502) Copy   

•   Source: SciCrunch Registry

http://www.sylvester.org/fcsr

Provides researchers with sophisticated methods for analysis and preparative sorting of both normal and tumor cells. Helps researchers to measure parameters including apoptosis, gene expression, drug metabolism, immune responses and pathways of cellular activation, both normal and tumor related. Provides access to high parameter cytometry instrumentation including spectral cytometry, mass cytometry and imaging mass cytometry.

Proper citation: University of Miami Sylvester Flow Cytometry Shared Resource Core Facility (RRID:SCR_022501) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/b/bmi/resource-service

Provides computational resources, services, and support to investigators including clinical research informatics, application and technology development, and bioinformatics analyses.

Proper citation: Cincinnati Children's Hospital Biomedical Informatics Core Facility (RRID:SCR_022622) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/genomics/about/

Full service sequencing facility to assist with genetic and genomic research. Part of Integrated Genomics Cores. Offers comprehensive library services, NextGen sequencing and alternative technologies including long reads. Offers library preparations and multiple sequencing platforms including MiSeq, HiSeq, NovaSeq, NextSeq, BioNano, Oxford Nanopore. Services also include using techniques and data analyses via sister core BARC.

Proper citation: UNC School of Medicine Integrated Genomics Cores High Throughput Sequencing Core Facility (RRID:SCR_022620) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/c/critical/medialab

Develops high quality video and animation to enhance medical education.

Proper citation: Cincinnati Children's Hospital Critical Care Media Lab Core Facility (RRID:SCR_022629) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/radcore

Clinical Imaging Core Service Center includes RADCORE, Tumor Response Assessment (TRAC) and Research imaging guided biopsies cores. Supports cancer clinical trials. RADCORE staff include clinical research professionals with range of expertise in imaging based clinical research protocols and offers services in consultation, management of research protocols and Radiology IND/IDE support office. Tumor Response Assessment Core (TRAC) team of Radiologist is skilled in evaluating tumor response imaging assessments for patients enrolled in cancer clinical trials being conducted at UPHS. Research imaging guided biopsies Interventional Radiology and technical staff provides consultation to define biopsy protocol and pathology tissue collection.

Proper citation: University of Pennsylvania Perelman School of Medicine Clinical Imaging Service Center Core Facility (RRID:SCR_022487) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/viral-vector-core

Provides research grade retroviral, lentiviral and adeno associated virus vectors. Offers generation of stable producer lines, and non-GMP quality control testing including vector titer by functional assay FACS or PCR, endotoxin, mycoplasma, and USP sterility testing.Provides standard packaging plasmids, the investigator provides the viral vector to be used for the production run.

Proper citation: Cincinnati Children's Hospital Viral Vector Core Facility (RRID:SCR_022641) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/translational-trial-development-support-laboratory

Provides facilities and expertise to support clinical assay development from technology developed in academic laboratories.Provides assay development and testing support for early phase clinical trials with focus on cell and gene therapy.

Proper citation: Cincinnati Children's Hospital Translational Trial Development and Support Laboratory Core Facility (RRID:SCR_022640) Copy   

•   Source: SciCrunch Registry