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http://derc.yale.edu/cores/physiology.aspx

Fee-for-service core facility for DRC members to facilitate in vivo diabetes-related research dealing with biological outcomes in normal, diabetic, and genetically manipulated rodents and mice. Physiology Core is divided into two Sub-cores: the Animal Surgery and Experimental Procedure Sub-core, which provides assistance with in vivo rodent studies the Analytical Sub-core, which assists with measurement of various analytes in rat and mouse samples.

Proper citation: Yale Diabetes Research Center Physiology Core Facility (RRID:SCR_015147) Copy   

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http://www.ucdenver.edu/academics/colleges/PublicHealth/research/centers/CAIANH/cdtr/Pages/Administrative-Core.aspx

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 30,2025. Administrative Core of the Center for American Indian and Alaska Native Diabetes Translational Research. The CAIANDTR is dedicated to extending prevention and management research of proven efficacy to both clinical and community settings, with the goal of improving the diabetes-related health of Native Americans.

Proper citation: Center for American Indian and Alaska Native Diabetes Translational Research Administrative Core (RRID:SCR_015148) Copy   

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http://diabetesresearchcenter.dom.wustl.edu/diabetes-models-phenotyping-core/

Core facility that provides services to multiple funded research projects in the area of diabetes and its complications so that rigorous experiments performed in model systems have the potential to yield compelling results that can be translated to a clinical context.

Proper citation: Washington University School of Medicine Diabetes Research Center Diabetes Models Phenotyping Core Facility (RRID:SCR_015156) Copy   

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https://labnodes.vanderbilt.edu/tmescsr

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 30,2025.Core facility that provides services, consultation and collaboration to enable the generation, storage and regeneration of genetically altered mice at Vanderbilt.

Proper citation: Vanderbilt Diabetes Research and Training Center Transgenic Mouse and ES Cell Shared Resource (RRID:SCR_015154) Copy   

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http://www.einstein.yu.edu/centers/diabetes-translational-research/phhs/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 30,2025. Core facility that supports research that promotes the health of populations with or at risk for diabetes. The Core addresses how to improve the uptake of type 2 diabetes research findings into practice and disseminate effective interventions across health care and community settings.

Proper citation: New York Regional Center for Diabetes Translation Research Population Health and Health Systems Core (RRID:SCR_015158) Copy   

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http://www.ucdenver.edu/academics/colleges/PublicHealth/research/centers/CAIANH/cdtr/Pages/Resource-Cores.aspx

Provides access to the CAIANDTR engagement core, technology core, sustainability core, and implementation, dissemination, and diffusion core.

Proper citation: Center for American Indian and Alaska Native Diabetes Translational Research Resource (RRID:SCR_015152) Copy   

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https://diabetes.med.umich.edu/partners/michigan-diabetes-research-center-mdrc/cores/microscopy-and-image-analysis-core-miac

Provides MDRC researchers with expert consultation, training and support for routine and advanced microscopy and image analysis techniques. Services include Consultation and Advice on Microscopy and Immunohistochemistry, Cryosection Service, Confocal Microscopy, Image Analysis, Widefield Light Microscopy,Live Cell Microscopy,Training and Education.

Proper citation: Michigan Diabetes Research Center Microscopy and Image Analysis Core Facility (RRID:SCR_015118) Copy   

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http://www.med.upenn.edu/idom/drc/cores/metacore.html

Core which aims to develop and validate metabolomic methods and data analysis software and provide high quality routine metabolomic services. Its services include quantitation of selected water-soluble metabolites, fatty acids, and lipids, quantitation of metabolic fluxes using stable isotope tracers, and identification of novel metabolites involved in diabetes pathophysoiology.

Proper citation: Penn Diabetes Research Center Metabolomics Core (RRID:SCR_015122) Copy   

•   Source: SciCrunch Registry

https://www.iths.org/resources/directory/listing/drc-human-studies-core-university-of-washington

Core facility that provides specialized technical resources and expertise to enhance the efficiency, productivity and multidisciplinary nature of clinical research performed by Diabetes Research Center (DRC)-affiliated investigators.

Proper citation: University of Washington Diabetes Research Center Human Studies Core Facility (RRID:SCR_015127) Copy   

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http://depts.washington.edu/diabetes/cell-function-analysis-core/

Core facility that supports the Diabetes Research Center affiliates by offering precise real time functional analysis of intact cells and primary tissue. The Cell Function Analysis Core also provides an islet isolation service, which gives affiliates easy access to primary tissue/cells ex vivo.

Proper citation: University of Washington Diabetes Research Center Cell Function Analysis Core Facility (RRID:SCR_015128) Copy   

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http://drtc.bsd.uchicago.edu/molecular-biology-and-genetics-core-laboratory-about/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Molecular biology and genetics core which helps independently funded investigators with an interest in diabetes mellitus and other metabolic disorders to clone, sequence and characterize cDNAs and genes of interest. It also provides research tools and expertise to enable investigators to discover how genetic variation in diabetes genes leads to hyperglycemia.

Proper citation: University of Chicago Diabetes Research and Training Center Molecular Biology and Genetics Core Laboratory (RRID:SCR_015129) Copy   

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http://drtc.bsd.uchicago.edu/physiology-core-about/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core whose goal is to facilitate the use of model organisms in diabetes and metabolism-related research. The Core provides access to resources, technology, equipment and services for the generation and study of genetically modified mice and other model organisms; consultation on experimental design and analysis; technology development; and opportunities for collaboration and training.

Proper citation: University of Chicago Diabetes Research and Training Center Animal Models and Physiology Core (RRID:SCR_015134) Copy   

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http://www.uab.edu/shp/drc/interventions-translational-core-links

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides expertise and services that range from methods of intervention development, basic study design and data analysis, and cutting-edge methodologies in measurement, to subject recruitment and retention strategies with an emphasis on increasing minority participation.

Proper citation: University of Alabama at Birmingham Diabetes Research Center Interventions and Translation Core (RRID:SCR_015135) Copy   

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https://diabetescenters.org/cores/ucsd-ucla-human-genetics-core

Core provides services such as assistance in the development and successful completion of well-designed genetic studies, establishment and storage of EBV-transformed lymphoblastoid cell lines (LCLs), as well as PAXgene tubes, and specialized (e.g., the exome chip) single nucleotide polymorphism (SNP) testing, candidate gene sequencing, whole exome sequencing (WES), whole genome sequencing (WGS), and large-scale gene methylation analysis.

Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Human Genetics Core Facility (RRID:SCR_015099) Copy   

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http://www.niaid.nih.gov/about/organization/dait/pages/csgadp.aspx

Collaborative network of investigators with a focus on prevention of autoimmune disease, defined as halting the development of autoimmune disease prior to clinical onset by means other than global immunosuppression, and an emphasis on Type 1 diabetes. Its mission is to engage in scientific discovery that significantly advances knowledge for the prevention and regulation of autoimmune disease. The specific goals enunciated in pursuit of this mission are: * To create improved models of disease pathogenesis and therapy to better understand immune mechanisms that will provide opportunities for prevention strategies * To use these models as validation platforms with which to test new tools applicable to human studies * To encourage core expertise and collaborative projects designed for rapid translation from animal to human studies, emphasizing the development of surrogate markers for disease progression and/or regulation which can be utilized in the context of clinical trials

Proper citation: Cooperative Study Group for Autoimmune Disease Prevention (RRID:SCR_006803) Copy   

•   Source: SciCrunch Registry

http://www.oucom.ohiou.edu/Biorepository/biorepository_inventory.htm

Plasma and cell fractions obtained from patients with Diabetes and endocrine diseases and their first degree relatives who agreed to participate in the development of the biorepository. Plasma is aliquoted into multiple specimen containers and stored at -80C. Cell fractions are subjected to DNA and RNA fractionation, aliquoted into multiple specimen containers, and frozen at -70 to -80 degrees centigrade. Anyone who would like to obtain samples from the Biorepository must provide evidence that they have adequate training in the use of bloodborne pathogens, as outlined by OSHA. The investigator must agree to indemnify and hold harmless the Ohio University Diabetes/Endocrine Diseases Biorepository, the Appalachian Rural health Institute, and the Ohio University College of Osteopathic Medicine from any claims, liability, costs, and damages.

Proper citation: Ohio U Diabetes Endocrine Biorepository (RRID:SCR_013435) Copy   

•   Source: SciCrunch Registry

http://www.ndep.nih.gov/

Federal government public education program that promotes diabetes prevention and control. They aim to reduce the morbidity and mortality associated with diabetes and its complications. The NDEP is jointly sponsored by the National Institutes of Health and the Centers for Disease Control and Prevention and over 200 partner organizations. Target audiences include people with diabetes and those at risk, including the racial and ethnic populations disproportionately affected by the disease, health care providers and payers and purchasers of health care.

Proper citation: National Diabetes Education Program (RRID:SCR_001477) Copy   

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http://www.bsc.gwu.edu/dpp/protocol.htmlvdoc

Observational clinical trial studying the long term effect of diet and exercise and the diabetes medication, metformin, on the delay of type 2 diabetes in participants of the Diabetes Prevention Program (DPP). The Diabetes Prevention Program (DPP) was a multi-center trial examining the ability of an intensive lifestyle or metformin to prevent or delay the development of diabetes in a high risk population due to the presence of impaired glucose tolerance (IGT). The DPP has ended early demonstrating that lifestyle reduced diabetes onset by 58% and metformin reduced diabetes onset by 31%. The DPPOS is designed to take advantage of the scientifically and clinically valuable DPP participants. This group of participants is nearly 50% minority and represents the largest IGT population ever studied. Clinically important research questions remain that focus on 1)durability of the prior DPP intervention, 2) determination of the clinical course of precisely known new onset diabetes, in particular regarding CVD, CVD risk factors and atherosclerosis and microvascular disease, 3)close examination of these topics in men vs women and in minority populations. More than 87% of the original surviving DPP cohort has joined DPPOS as of December, 2007 and, to date, after 5 years of DPPOS and 10 years of combined DPP/DPPOS, 93% of the DPPOS cohort continue to attend annual follow-up visits. Interim analyses performed after 5 years of DPPOS have demonstrated a durable effect of diabetes prevention associated with the lifestyle and metformin interventions with 34 and 19% reductions in diabetes incidence, respectively, compared with the placebo group. Interim analyses also reveal significant reductions from baseline in CVD risk factors in the lifestyle intervention group, but with decreased utilization of glucose-lowering and lipid-lowering medications. Analyses of the participants in the placebo group who have developed diabetes during DPP/DPPOS, compared with those who have remained non-diabetic, reveal an increased frequency of retinopathy and microalbuminuria. The current, updated protocol describes the DPPOS including the revisions incorporated to complete the second five-years of the study. DPPOS participants have blood samples stored at the time of each annual visit. Specimens are stored at the study CBL until after the primary study outcomes are reported. DNA samples were previously collected and are stored at the NIDDKsample repository for DPP participants.

Proper citation: Diabetes Prevention Program Outcomes Study (RRID:SCR_001502) Copy   

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https://labnodes.vanderbilt.edu/community/profile/id/2228

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 13,2025.Core facility that provides access to isolated pancreatic islets from normal and diabetic models and performs islet functional analysis. The IPA Core also provides solutions for high-resolution whole slide imaging and access to image analysis tools for quantitative assessment of pancreatic islet morphology.

Proper citation: Vanderbilt Diabetes Research and Training Center Islet Procurement and Analysis Core (RRID:SCR_000896) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/mouse.html

Core which provides researchers with resources for performing metabolic studies in mice. It also provides services, innovative techniques, and helpful consultation to both experienced and novice investigators with regards to metabolic questions.

Proper citation: Penn Diabetes Research Center Mouse Phenotyping Physiology and Metabolism Core (RRID:SCR_000888) Copy   

•   Source: SciCrunch Registry