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http://www.nersc.gov

Supercomputer user facility operated by Lawrence Berkeley National Laboratory for the United States Department of Energy Office of Science.Houses high performance computing and data systems used by scientists at national laboratories and universities around the country.

Proper citation: University of California at Berkeley National Energy Research Scientific Computing Core Facility (RRID:SCR_021318) Copy   

•   Source: SciCrunch Registry

https://gladstone.org/science/flow-cytometry-core

Core offers operation, training and consultation on both cell sorters and analyzers.Our core comprises BDFACsAria II, two BDFACSAria Fusions, Fortessa X-20 and Attune, with analyzing and sorting up to 18 colors possible. Core also offers antibody staining, protocol optimization and data analysis services.

Proper citation: Gladstone Institutes Gladstone Flow Cytometry Core Facility (RRID:SCR_021714) Copy   

•   Source: SciCrunch Registry

https://www.ed.ac.uk/clinical-research-facility/core-services/mass-spectrometry

Core is part of Edinburgh Clinical Research Facility, situated in the Centre for Cardiovascular Sciences in the Queen's Medical Research Institute. We train and host undergraduate students, PhD and post-doctoral students in practical skills and mass spectrometry operation. We have expertise in sample preparation, separation and mass spectrometry analysis for targeted small molecule analysis in clinical and pre-clinical studies. We operate under Good Clinical Practice for laboratories for clinical studies. Steroids, drugs and endogenous molecules and metabolic pathways in plasma, serum, tissue. We also have Imaging Mass spectrometry capabilities with a Waters Synapt G2Si, MALDI and DESI.

Proper citation: University of Edinburgh Clinical Research Mass Spectrometry Core Facility (RRID:SCR_021833) Copy   

•   Source: SciCrunch Registry

https://biotech.unl.edu/proteomics-and-metabolomics#tab1

Provides services using mass spectrometry, including identification and relative quantification of proteins and several advanced methods for profiling and quantitation of small molecules.Provides outreach and education program including workshops,seminars and courses.Proteomics services include Bottom-up Proteomics of whole organisms, organs, organelles, tissues, cell pellets, pulldowns, complex or single protein mixes from solutions or gels;Quantification by label-free or multiplexed labeling techniques with microscale subfractionation to increase coverage;Post Translational Modification Characterization especially phosphopeptide enrichment from whole organism digests, but also ubiquitylation, acetylation, etc.Metabolomics services include Untargeted Quantification of small molecules;Primary metabolism using GC-MS and NIST/Fiehn Libraries;Secondary metabolism using LC-MS and Progenesis QI, NIST Library, mzCloud;Targeted Quantification using HPLC or LCMS.

Proper citation: University of Nebraska Lincoln Nebraska Center for Biotechnology Proteomics and Metabolomics Core Facility (RRID:SCR_021314) Copy   

•   Source: SciCrunch Registry

https://www.chla.org/research/cellular-imaging-core

Core provides equipment in microscopy and digital imaging. Primary focus is technology transfer and provision of facilities for acquisition and analysis of histological and cytological preparations. Provides training in the use of imaging instrumentation and in the application of image analysis procedures for generation of quantitative data.

Proper citation: University of Southern California CHLA Cellular Imaging Core Facility (RRID:SCR_021964) Copy   

•   Source: SciCrunch Registry

https://research.utexas.edu/cbrs/cores/bms/

Proteomics and Metabolomics services and collaborative efforts are provided at Biological Mass Spectrometry Facility. We use high resolution Orbitrap mass spectrometers with UPLC at high flow for metabolomics and nanoUPLC for proteomics work. We have Bruker Autoflex for self service MALDI. Our proteomics services are protein ID, quantitation, and modification analysis, with fractionation for deeper coverage and de novo sequencing of mAbs available. We collaborate for customized projects. We have untargeted metabolomics for quantitative or qualitative analysis of extracted metabolites using C18 column.

Proper citation: University of Texas at Austin Biological Mass Spectrometry Proteomics Core Facility (RRID:SCR_021728) Copy   

•   Source: SciCrunch Registry

https://www.stowers.org/technology/genome-engineering

Core supports genome engineering using CRISPR technology. Provide services to generate knockouts, insertions, deletions, and point mutations in various organisms. Services for genome engineering include guideRNA design, homology-directed repair template design, production of modified mammalian cell lines, preparation of reagents for delivery to embryos, and mutation detection by targeted deep sequencing. Pooled screening is also coordinated and supported by our team.We acquire, prepare, and validate pooled libraries as an Institute resource. In coordination of our pooled screen workflow, we work with other teams to track the progress of these projects. Once resulting cell populations from the screen are delivered, our team does genomic DNA purification, target amplification, and preparation for NGS. We now offer a TAIL-PCR service to identify the location of random integration events. We have successfully identified locations in killifish, fly, zebrafish, and sea anemone.Team is responsible for maintaining and distributing clone and vector collections for the Institute.

Proper citation: Stowers Institute for Medical Research Genome Engineering Core Facility (RRID:SCR_021729) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/genomics-facility

Full Service DNA Sequencing and Genotyping facility. Offers Sanger,Fragment Analysis, Illumina, RT and Digital PCR, Single Cell, large projects, sample/library prep and QC.Houses state of the art instruments for all your sequencing needs including, capillary DNA analysis, single cell applications, long read capabilities. We also provide many instruments that can be operated by you for sample preparation and quality control of all sample types.

Proper citation: Cornell University BRC Genomics Core Facility (RRID:SCR_021727) Copy   

•   Source: SciCrunch Registry

https://multiplex.forsyth.org/

Core provides researchers access to multiplex analysis of any sample type using commercially available or in house developed assays.Includes simultaneous measurement of multiple biomarkers in single small sample volume. Offers expertise in sample preparation and handling and knowledge that comes with extensive experience.

Proper citation: Forsyth Institute Multiplex Core Facility (RRID:SCR_021783) Copy   

•   Source: SciCrunch Registry

https://biomedimaging.utexas.edu/

Multimodal imaging facility that supports human and preclinical imaging research. Hosts range of systems for MRI, PET, CT and optical imaging and accommodates both independent and assisted use for human MRI and PET/CT on its instruments. Provides in house training in scanner safety and operation and supports range of task for functional MRI studies.

Proper citation: University of Texas at Austin Biomedical Imaging Center Core Facility (RRID:SCR_021898) Copy   

•   Source: SciCrunch Registry

https://www.uni.lu/lcsb-en/facilities/genomics-platform/

Core offers next generation sequencing services.Provided sequencers include NextSeq2000 and MiSeq from Illumina, and MinION nanopore sequencer from Oxford Nanopore Technologies. Illumina sequencers allow sequencing tunable read lengths up to 300 bases of single as well as paired end runs while MinION sequencer complements by ultra long read lengths up to several hundreds of kilobases. Together this offers high flexibility for the different sequencing needs. Platform offers full service, starting with advice in experimental design up to sequencing data generation. Receiving RNA or DNA samples, sample quality check, sample shearing, library preparation, sequencing run, raw data generation and preliminary data quality control report is performed. General applications include RNA sequencing, metagenomics, small genome sequencing, targeted gene sequencing, amplicon sequencing, and HLA typing. Upon user request, sequencing platform works closely with bioinformatics platform to offer downstream data analysis. Besides wide range of standard services, platform also offers new method development.

Proper citation: University of Luxembourg LCSB Genomics Platform Core Facility (RRID:SCR_021931) Copy   

•   Source: SciCrunch Registry

https://vmmpc.org/

Centralized resource for study of mouse models of diabetes, obesity, and related disease. Includes animal housing, energy balance, telemetry, and experiment rooms and surgical suites. Develops, standardizes, and provides surgical and experimental services for phenotyping mice. Surgical procedures include venous and arterial catheterizations, cannulation of brain regions, bariatric surgeries, and islet transplantations. VMMPC uses flexible platforms to study nutrient metabolism and energy balance that can be readily adapted for specific experimental requirements. Use of dual arterial and venous catheter implantation permit glucose clamps, treadmill exercise, metabolic flux analyses, and other procedures to be studied without the stress of handling mice. VMMPC offers courses annually to disseminate research laboratory practices for mouse.

Proper citation: Vanderbilt University Mouse Metabolic Phenotyping Center Core Facility (RRID:SCR_021939) Copy   

•   Source: SciCrunch Registry

https://www.kcl.ac.uk/research/microscopy-innovation-centre

Core works with academic and industrial partners to develop and house advanced microscopy instrumentation and analysis tools.Provides custom microscopes to support users in their advanced imaging needs.

Proper citation: Kings College London Microscopy Innovation Centre Core Facility (RRID:SCR_021791) Copy   

•   Source: SciCrunch Registry

https://wcmc.corefacilities.org/service_center/show_external/5753/human_immune_monitoring_core_himc

Core provides technology platforms and services for single cell, in situ, and multiomic analysis for cutting edge immunology research and clinical studies to help make impactful discoveries and develop improved treatments for human diseases. Services include Spectral flow cytometry (Cytek Aurora), Imaging mass cytometry (Fluidigm Hyperion), CyTOF mass cytometry (Fluidigm Helios).

Proper citation: Cornell University Weill Medical College Human Immune Monitoring Core Facility (RRID:SCR_021669) Copy   

•   Source: SciCrunch Registry

https://medicine.tamu.edu/imil

Core supports research progress and grant development by encouraging researchers to explore advanced imaging modalities and to incorporate them into their existing research programs.Provides technical expertise and cutting edge microscope systems to support research of faculty and staff of Texas A&M University Health Science Center, Texas A&M University, and all other campuses.IMIL includes six microscopy rooms, supporting facilities, and image processing station.Technical staff is available to train and assist with design, implementation, and analysis of experiments as well as assist in troubleshooting.

Proper citation: Texas A&M Health Science Center Integrated Microscopy and Imaging Laboratory Core Facility (RRID:SCR_021637) Copy   

•   Source: SciCrunch Registry

https://cryoem.sites.ucsc.edu/

Biomolecular facility equipped with JEOL 120kV and Glacios 200 kV with K2 Summit direct detector. Provides insights and high throughput data collection and analysis,single particle analysis, sample screening, and high resolution reconstruction., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of California at Santa Cruz Biomolecular Cryo Electron Microscopy Core Facility (RRID:SCR_021755) Copy   

•   Source: SciCrunch Registry

https://research.utexas.edu/cbrs/cores/mfc/

Provides light microscopy and flow cytometry equipment and services for ultra structural analysis of variety of sample types. Offers assisted use and training on its instrumentation and consultations on related research. Provides access to both standard and high-end imaging instrumentation to all levels of users.

Proper citation: University of Texas at Austin Microscopy and Flow Cytometry Core Facility (RRID:SCR_021756) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/pathology/molecular-pathology

Molecular Pathology Section offers clinical grade sample processing and molecular testing for research cases.All services are performed in CLIA certified environment and all molecular assays are accompanied by full data analysis including bioinformatics analysis for NGS data.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Molecular Pathology Core Facility (RRID:SCR_021995) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/animal-imaging/irradiation

Core specializes in targeted irradiation of small animals for use in preclinical trials of radiation therapy. Through use of XRAD-SmART Irradiator, core can use x-ray fluoroscopy and on board CBCT to accurately irradiate small lesion areas while protecting normal tissue. Provides experiment design, data analysis, and dosimetry calculations, as well as longitudinal acquisition of CBCT for temporal assessment of tumor growth kinetics.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Small Animal Image Guided Radiation Therapy Core Facility (RRID:SCR_021996) Copy   

•   Source: SciCrunch Registry

http://core-facility.iimcb.gov.pl/

Offers comprehensive selection of molecular biophysics techniques such as SPR, SEC-MALS, AUC, ITC, CD, FT-IR useful in characterization of macromolecule size and intermolecular interactions.

Proper citation: International Institute of Molecular and Cell Biology in Warsaw, Biophysics and Bioanalytics Facility (RRID:SCR_021630) Copy   

•   Source: SciCrunch Registry