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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
This Week in Virology (TWiV) is a podcast - or netcast, as some prefer to call them, since you don''t need an iPod to listen - about viruses - the kind that make you sick. Professors Vincent Racaniello, Dickson Despommier, Rich Condit and science writer Alan Dove and guests deconstruct viruses, how they cause illness, and how you can prevent infections. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008; Rich Condit, a poxvirologist, joined in 2009, and Kathy Spindler, an adenovirologist, joined in 2012. We''ve had quite a few guests on the show and we''re always trying to get more. Transcripts A few readers have been kind enough to produce transcripts for several TWiV episodes.
Proper citation: TWiV - This Week in Virology (RRID:SCR_006097) Copy
http://neuro.imm.dtu.dk/software/brede/
A package for neuroinformatics and neuroimaging analysis mostly programmed in Matlab with a few additional programs in Python and Perl. It allows coordinate-based meta-analysis and visualization, neuroimaging analysis of voxel or regional data - not the original data but rather the summary images (e.g., statistical parametric images) and location data in stereotactic space. Among the algorithms implemented are kernel density estimation (for coordinate-based meta-analysis), independent component analysis, non-negative matrix factorization, k-means clustering, singular value decomposition, partial correlation analysis with permutation testing and partial canonical correlation analysis. Visualization of coordinate, surfaces and volumes are possible in 2D and 3D. Generation of HTML for results are possible and algorithms can be accessed from the command line or via a flexible graphical interface. With the Brede Toolbox comes the Brede Database with a small coordinate database from published neuroimaging studies, and ontologies for, e.g., brain function and brain regions.
Proper citation: Brede Toolbox (RRID:SCR_006204) Copy
http://www.benthamscience.com/open/index.htm
Publish over 230 plus peer-reviewed open access journals. These free-to-view online journals cover all major disciplines of science, technology, medicine and social sciences. Bentham OPEN offers its ''Complimentary Membership'' to International R & D organizations, institutes and universities. This opportunity will entitle authors from different member institutes to a special discount of 30% in the open access publication fee for submission of articles to Bentham OPEN journals. Additionally, input and contributions from associate institutes would also be recognized and a link to their respective Website would be displayed on the Bentham OPEN membership page. The member institution''s logo will also be published on the same page. Bentham Open Membership provides the following advantages: * Possibility to explore 73 distinct disciplines by means of publishing in 239 open access journals. * Free access to all provides prospects of higher citations. * Author(s) own the copyrights to their published articles. * High standard criteria for peer-review. * Unbound right to read, download or print open access articles. * Access to a range of articles in printed form such as short communications, full length research articles, reviews or conference proceedings. * Simple steps from submission to publication, leading to fast turn-around. * Possibility of archiving published articles. The complimentary membership is valid for a span of one year and upon completion of the prescribed period, it is renewed by mutual interest and agreement. If you find the above mentioned details relevant, then kindly contact us via e-mail at membership_at_benthamscience.org or oa_at_benthamscience.org.
Proper citation: Bentham OPEN (RRID:SCR_006202) Copy
http://riodb.ibase.aist.go.jp/riohomee.html
RIO-DB (Research Information Database) is a multimedia one concerning various research information which is developed and accumulated through many AIST R&D projects. RIO-DB project aims to contribute to the creation and promotion of new businesses from academic society to industrial community by spreading the research information via internet. This is a portal to many database resources in the following categories: * Standard * Chemistry * Earth sciences * Energy * Biology * Material * Information Technology * Safety
Proper citation: RIO-DB - Research Information Database (RRID:SCR_006105) Copy
http://athina.biol.uoa.gr/DAM-Bio/
An integrated environment designed to support protein sequence and structure analysis on the web.
Proper citation: DAM-Bio (RRID:SCR_006226) Copy
Data resource catalog that collates metadata on bioinformatics Web-based data resources including databases, ontologies, taxonomies and catalogues. An entry includes information such as resource identifier(s), name, description and URL. ''''Query'''' lines are defined for each resource that describe what type(s) of data are available, in what format, how (by what identifier) the data can be retrieved and from where (URL). DRCAT was developed to provide more extensive data integration for EMBOSS, but it has many applications beyond EMBOSS. DRCAT entries (including ''''Query'''' lines) are annotated with terms from the EDAM ontology of common bioinformatics concepts.
Proper citation: DRCAT Resource Catalogue (RRID:SCR_005931) Copy
http://bioinformatics.biol.uoa.gr/LepChorionDB/
A relational database of Lepidoptera chorion proteins. The proteinaceous Lepidopteran chorions are used in our lab, as a model system towards unraveling the routes and rules of formation of natural protective amyloids. Therefore, we constructed LepChorionDB a relational database, containing all Lepidoptera chorion proteins identified to date. Lepidoptera chorion proteins can be classified in two major protein families, A and B. This classification was based on multiple sequence alignments of conserved key residues, in the central domain of, well characterized, silkmoth chorion proteins. These alignments were used to build Hidden Markov Models in order to search various DataBases. This work was a collaboration of the Department of Cell Biology and Biophysics, University of Athens and the Centre of Immunology & Transplantation Biomedical Research Foundation, Academy of Athens.
Proper citation: LepChorionDB (RRID:SCR_006222) Copy
http://aias.biol.uoa.gr/OMPdb/
A database of Beta-barrel outer membrane proteins from Gram-negative bacteria. The web interface of OMPdb offers the user the ability not only to view the available data, but also to submit advanced queries for text search within the database''s protein entries or run BLAST searches against the database. The most up-to-date version of the database (as well as all past versions) can be downloaded in various formats (flat text, XML format or raw FASTA sequences). For constructing OMPdb, multiple freely accessible resources were combined and a detailed literature search was performed. The classification of OMPdb''s protein entries into families is based mainly on structural and functional criteria. Information included in the database consists of sequence data, as well as annotation for structural characteristics (such as the transmembrane segments), literature references and links to other public databases, features that are unique worldwide. Along with the database, a collection of profile Hidden Markov Models that were shown to be characteristic for Beta-barrel outer membrane proteins was also compiled. This set, when used in combination with our previously developed algorithms (PRED-TMBB, MCMBB and ConBBPRED) will serve as a powerful tool in matters of discrimination and classification of novel Beta-barrel proteins and whole-genome analyses., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: OMPdb (RRID:SCR_006221) Copy
https://fairsharing.org/standards/
Catalogue to: 1, centralize community-developed bioscience standards, linking to policies, other portals, open access resources and lists of tools and databases implementing the standards; 2. develop and maintain a set of criteria for assessing the usability and popularity of the standards, also the interoperability and relations among them; 3. foster interoperability, addressing overlaps and duplication of efforts that hamper their wider uptake and interfere with the creation of standards-compliant systems. Research community, funding agencies, and journals participate in the development of reporting standards for the bioscience domain to ensure that shared experiments are reported with enough information to be comprehensible and (in principle) reproducible, compared or integrated. Similar trends in both the regulatory arena and commercial science. The BioSharing catalogue classifies standards into three types: * reporting requirements (minimal information checklists to report of the same core set of information) * terminological artifacts (such as controlled vocabularies and ontologies to describe the information) * exchange formats (to communicate the information) You can sort columns and browse the reporting guidelines content, or you can view all the standards, or reporting guidelines, or terminological artifacts or exchange formats only. Contribute and help build the catalogue.
Proper citation: FAIRSharing Catalogue of Standards (RRID:SCR_005926) Copy
Distributed repository of anatomo-functional data and of simulation algorithms, fully integrated into a seamless simulation environment and directly accessible. This infrastructure will be used to create the physiome of the human musculo-skeletal system.
Proper citation: LHP LHDL (RRID:SCR_005928) Copy
http://dictybase.org/Dicty_Info/dicty_anatomy_ontology.html
An ontology to describe Dictyostelium where the structural makeup of Dictyostelium and its composing parts including the different cell types, throughout its life cycle is defined. There are two main goals for this new tool: (1) promote the consistent annotation of Dictyostelium-specific events, such as phenotypes (already in use), and in the future, of gene expression information; and (2) encourage researchers to use the same terms with the same intended meaning. To this end, all terms are defined. The complete ontology can be browsed using EBI''s ontology browser tool. (http://www.ebi.ac.uk/ontology-lookup/browse.do?ontName=DDANAT)
Proper citation: Dictyostelium Anatomy Ontology (RRID:SCR_005929) Copy
http://purl.org/spar/datacite/
An ontology written in OWL 2 DL to enable the metadata properties of the DataCite Metadata Kernel Specification version 2.2 (http://test.datacite.org/schema/meta/kernel-2.2/index.html) to be described in RDF. This version of the DataCite Ontology has been completely revised and significantly expanded to permit accurate mapping of this new version of the DataCite Metadata Kernel Specification to RDF.
Proper citation: DataCite Ontology (RRID:SCR_006215) Copy
http://athina.biol.uoa.gr/bioinformatics/GENEVITO/
A JAVA-based computer application that serves as a workbench for genome-wide analysis through visual interaction. GeneViTo offers an inspectional view of genomic functional elements, concerning data stemming both from database annotation and analysis tools for an overall analysis of existing genomes. The application deals with various experimental information concerning both DNA and protein sequences (derived from public sequence databases or proprietary data sources) and meta-data obtained by various prediction algorithms, classification schemes or user-defined features. Interaction with a Graphical User Interface (GUI) allows easy extraction of genomic and proteomic data referring to the sequence itself, sequence features, or general structural and functional features. Emphasis is laid on the potential comparison between annotation and prediction data in order to offer a supplement to the provided information, especially in cases of poor annotation, or an evaluation of available predictions. Moreover, desired information can be output in high quality JPEG image files for further elaboration and scientific use. GeneViTo has already been applied to visualize the genomes of two microbial organisms: the bacterion Chlamydia trachomatis and the archaeon Methanococcus jannaschii. The application is compatible with Linux or Windows ME-2000-XP operating systems, provided that the appropriate Java Runtime Environment (Java 1.4.1) is already installed in the system.
Proper citation: GeneVito (RRID:SCR_006211) Copy
http://www.bioconductor.org/packages/devel/bioc/html/deepSNV.html
Software package that provides quantitative variant callers for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. The algorithm is used for a comparative setup with a control experiment of the same loci and uses a beta-binomial model and a likelihood ratio test to discriminate sequencing errors and subclonal SNVs (single nucleotide variants).
Proper citation: deepSNV (RRID:SCR_006214) Copy
A visualization hub displaying sequencing data from the Roadmap Epigenomics project. It hosts high volume of tracks from ENCODE and Roadmap Epigenomics projects, supports multiple organisms, visualizes chromatin-interaction data (e.g. Hi-C), performs gene set view, gene plot, and many others. All delivered on the web at high performance.
Proper citation: VizHub (RRID:SCR_006209) Copy
http://www.umich.edu/~neurosci/
The Graduate Program at the University of Michigan was constituted in 1971, making it the longest-standing neuroscience graduate program in the United States. We are a collegial and interactive group of 75 students and 115 faculty that perform research across the breadth of the neuroscience field. Neuroscience graduate students on this campus form a cohesive group, which promotes interactions among the faculty, making the Graduate Program the nexus of the neuroscience community. Graduates receive a Ph.D. in Neuroscience, which provides tremendous flexibility in choosing one's career path. There are more than 100 alumni of our Program, and these graduates work in academic research, industrial research and development, academic medicine and biotechnology. Our program captures the excitement and interaction intrinsic to the field of neuroscience. Students can seek admission to the Neuroscience Program by three different routes direct application to the Neuroscience Program, application via the Program in Biomedical Sciences and application via the Medical Scientist Training Program.
Proper citation: University of Michigan Department of Neuroscience Graduate Program (RRID:SCR_006002) Copy
http://evolution.genetics.washington.edu/phylip.html
A free package of software programs for inferring phylogenies (evolutionary trees). The source code is distributed (in C), and executables are also distributed. In particular, already-compiled executables are available for Windows (95/98/NT/2000/me/xp/Vista), Mac OS X, and Linux systems. Older executables are also available for Mac OS 8 or 9 systems.
Proper citation: PHYLIP (RRID:SCR_006244) Copy
http://www.semantic-mediawiki.org/wiki/Semantic_MediaWiki
A free, open-source extension to MediaWiki - the wiki software that powers Wikipedia - that helps to search, organize, tag, browse, evaluate, and share the wiki''s content. While traditional wikis contain only text which computers can neither understand nor evaluate, SMW adds semantic annotations that allow a wiki to function as a collaborative database. Semantic MediaWiki introduces some additional markup into the wiki-text which allows users to add semantic annotations to the wiki. While this first appears to make things more complex, it can also greatly simplify the structure of the wiki, help users to find more information in less time, and improve the overall quality and consistency of the wiki. A large number of related extensions have been created that extend the ability to edit, display and browse through the data stored by SMW: the term Semantic MediaWiki is sometimes used to refer to this entire family of extensions.
Proper citation: Semantic MediaWiki (RRID:SCR_006246) Copy
http://bioinformatics.charite.de/voronoia/
Voronoia is a program suite to analyse and visualize the atomic packing of protein structures. It is based on the Voronoi Cell method and can be used to estimate the quality of a protein structure, e.g. by comparing the packing density of buried atoms to a reference data set or by highlighting protein regions with large packing defects. Voronoia is also targeted to detect locations of putative internal water or binding sites for ligands. Accordingly, Voronoia is beneficial for a broad range of protein structure approaches. It is applicable as a standalone version coming with a user friendly GUI or, alternatively, as a Pymol Plugin. Finally, Voronoia is also available as an easy to use webtool to process user defined PDB-files or to asses precalculated packing files from DOPP, the regularly updated Dictionary of Packing in Proteins.
Proper citation: Voronoia (RRID:SCR_006005) Copy
http://www.birncommunity.org/tools-catalog/human-imaging-database-hid/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented October 5, 2017.
Database management system developed to handle the increasingly large and diverse datasets collected as part of the MBIRN and FBIRN collaboratories and throughout clinical imaging communities at large. The HID can be extended to contain relevant information concerning experimental subjects, assessments of subjects, the experimental data collected, the experimental protocols, and other metadata normally included with experiments.
Proper citation: Human Imaging Database (RRID:SCR_006126) Copy
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