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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://research.med.psu.edu/core-facilities/zebrafish/
Provides Penn State research community with modern, centralized facility for housing, breeding and performing experiments with zebrafish.Provides physical and intellectual infrastructure for investigators whose research can benefit from use of zebrafish as model system.
Proper citation: Penn State Hershey College of Medicine Zebrafish Functional Genomics Core Facility (RRID:SCR_021199) Copy
https://www.etsu.edu/com/mbcf/
Core provides Genomics, Transcriptomics and Proteomics Services to researchers.
Proper citation: East Tennessee State University Quillen College of Medicine Molecular Biology Core Facility (RRID:SCR_021106) Copy
https://www.wadsworth.org/research/cores/alm
Core facility is designed for Imaging living cells or tissues, Fluorescence imaging, Image analysis. Provides imaging of adherent cells or tissue fragments,drug delivery using perfusion chamber, gas exchange for the growth media, Rose chambers for imaging, image processing and analysis software to assist in data analysis and interpretation.
Proper citation: New York State Department of Health Wadsworth Center Advanced Light Microscopy and Image Analysis Core Facility (RRID:SCR_021104) Copy
https://www.colorado.edu/lab/nmr/
Core serves research needs of entire campus community as well as outside research entities. Facility maintains a variety of NMR spectrometers at variety of magnetic fields to support research needs.
Proper citation: Colorado University at Boulder Nuclear Magnetic Resonance Spectroscopy Core Facility (RRID:SCR_019311) Copy
https://www.biotech.cornell.edu/core-facilities-brc/facilities/epigenomics-facility
Provides service that maps protein DNA interactions genome wide, tracks experimental metadata, and implements quality controlled data processing and research based analysis pipelines. Provides epigenomic and bioinformatic research resources and services that include sample preparation services and data generation. Open source platforms enable and reinforce FAIR data practices. Core is able to receive and process cell and tissue samples for various diagnostic epigenetic assays.
Proper citation: Cornell University BRC Epigenomics Core Facility (RRID:SCR_021287) Copy
https://nuance.northwestern.edu/facilities/biocryo/index.html
Provides source for characterization of biological, soft matter, and hybrid samples with TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and STEM (Scanning Transmission Electron Microscopy) at cryogenic or at ambient temperature.Provide expertise and access to equipment for cryofixation and processing of frozen hydrated samples by high pressure freezing, plunge freezing, freeze fracturing, cryo ultramicrotomy, freeze substitution, and turbo freeze-drying. Conventional samples can be processed at ambient temperature with chemical fixation, dehydration, and resin embedding, or critical point drying. Offers EDX (Energy Dispersive X-ray Spectroscopy) for elemental analysis.Offers training on instruments and sample preparation techniques.BioCryo staff mentors new users, advises on experimental design, and collaborates with researchers in experiments with challenging and unconventional samples.BioCryo Facility participates in numerous educational and outreach events, e.g. workshops, seminars, demos, and facility tours.
Proper citation: Northwestern University NUANCE BioCryo Core Facility (RRID:SCR_021288) Copy
http://web.ncifcrf.gov/atp/default.asp?LabID=12&page=labs
Comprises six service groups. Our services are available to all NIH intramural researchers, and by interagency agreements to FDA and US Army at Ft. Detrick. We are happy to consult and distribute materials to not-for-profit institutions.Clone Optimization service include DNA cloning for protein expression; Gateway-based; fluorescent, epitope, solubility, purification tags; mutagenesis; vectors for insect/ baculovirus, mammalian, E. coli, P. pastoris, K. lactis. Microbial Expression: E. coli, P. pastoris, K. lactis, 2 mL to 60 L, autoinduction and IPTG; fully instrumented fermenters.Eukaryotic Expression service include insect / baculovirus, mammalian transient and stable, monoclonal antibodies.Protein Purification service include parallel microscale for process development; affinity and native, tag and endotoxin removal; scale-up to low gram scale.Virus Technology service include custom and stock adenovirus and lentivirus production; titer determination; promoter and reporter panels in lentivirus ready to deliver.Molecular Detection: qPCR and ELISA assaysdeveloped and executed, focused on human viruses in human samples; qPCR assays for mycoplasma and human pathogenic viruses contaminating cell lines; cell line identity testing.
Proper citation: Frederick National Laboratory Protein Expression Laboratory Core Facility (RRID:SCR_021286) Copy
https://strucbiol.pbsci.ucsc.edu/
Provides instrumentation, supplies, and expertise to assist researchers in structural characterization of biological macromolecules. Resources are available for crystallization and structure determination as wells as biophysical characterization of macromolecular stability and interactions.
Proper citation: University of California Santa Cruz Macromolecular Structure Function Core Facility (RRID:SCR_021283) Copy
https://biomedical-sciences.uq.edu.au/facilities/imaging-facilities
Provides microscopes for life science research, including number of confocals, widefield systems, slide scanners, and analysis packages. Provides analytic instruments such as flow cytometers, imaging systems, and PCR equipment among others. Our team consists of experienced biologists and are available to help you with experiment building, troubleshooting, and data analysis.
Proper citation: University of Queensland School of Biomedical Sciences Imaging and Analytics Core Facility (RRID:SCR_019246) Copy
Centralized, coordinated imaging facility.Provides electron and ion beam analytical microscopy instruments.Full service facility from extensive sample preparation laboratories to image processing tools and support.
Proper citation: Ohio State University Center for Electron Microscopy and Analysis Core Facility (RRID:SCR_021294) Copy
https://mcgill.ca/cftrc/platforms/primary-airway-cell-biobank-pacb
Nonprofit facility providing researchers worldwide with standardized, high-quality primary airway cells from normal and large variety of airway diseased donors with different genetic backgrounds, are essential for improving our understanding of CF and other respiratory diseases and for translational research to develop new therapeutic agents.The PACB is certified by the UBC Office of Biobank Education and Research Biobank Certification Program.
Proper citation: McGill University Primary Airway Cell Biobank Core Facility (RRID:SCR_020998) Copy
https://sites.google.com/ucsc.edu/ucsccrisprcore/home
Facility that provides CRISPR services and expertise to facilitate study of gene function. Services include project consultation, sgRNA design and cloning, lentivirus production, custom CRISPR cell line generation and genome wide CRISPR screen.
Proper citation: University of California at Santa Cruz CRISPR Core Facility (RRID:SCR_021207) Copy
Center composes network of core imaging facility locations for advanced optical imaging and basic electron microscopy located within the AHC/Medical School (1-151 Jackson Hall, Minneapolis) and College of Biological Sciences (23 Snyder Hall, St. Paul) on the University of Minnesota Twin Cities Campus.UIC cores serve internal and external research clients in design of imaging experiments, choice of and training on suitable imaging systems, and subsequent image processing, visualization and analysis.Provides advanced imaging systems including macro spectral confocal microscopy,wide-field light and fluorescence microscopy, spinning disk confocal, laser-scanning confocal microscopes, multi photon/Second Harmonic Generation microscopes, total internal reflectance microscope, laser capture micro-dissection, live cell imaging systems, scanning and transmission electron microscopy, whole animal fluorescence, bioluminescence and chemiluminescence imagers, gel, print and film scanners,poster printers, full sample preparation capabilities.
Proper citation: University of Minnesota University Imaging Centers Core Facility (RRID:SCR_020997) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 11, 2025. Interdisciplinary team of engineers and scientists, representing fields of physics, mathematics, and computer science, that combine their expertise in areas such as microscopy, lasers, optoelectronics, applied mathematics, image and signal processing, computer graphics, computer vision, statistics, software engineering, and biophysics, to develop imaging approaches for cell biology. Pioneers in high-resolution 3D imaging using wide-field fluorescence microscopy together with digital image deconvolution, and image visualization and quantitative analysis techniques, especially as applied to statistical analysis of images to determine co-localization of fluorescence markers inside cells.Research includes development and application of light microscopy and imaging in cell biology and biophysics.Developed TESM microscope that combines Total internal reflection fluorescence (TIRF) with Epi-fluorescence Structured illumination to provide new views of trafficking in near plasma membrane domain of cells.Provides custom-built, ultra-high-speed microscope system for imaging dynamics of intracellular calcium channel events, called calcium sparks, that are being found to regulate expanding array of cellular processes. Provides two photon fluorescence microscope for looking deep inside tissue, completing range from molecule to organism. Areas of ongoing technology research include high-speed, high-resolution imaging of live cells and tissues, novel image processing approaches, high-performance computing, and computer graphics.
Proper citation: University of Massachusetts Medical School Biomedical Imaging Group Core Facility (RRID:SCR_021201) Copy
The MIC Live Imaging and Physiology Core is a division of the Microscopy and Imaging Center of the UVM Larner College of Medicine. The Live Imaging and Physiology Core provides a wide range of imaging techniques mainly for live-cell, live-tissue and in-vivo preparations. We maintain a Noran/Prairie Technologies OZ LSCM (laser scanning confocal microscope), a DeltaVision RT restoration microscopy system, a Zeiss/BioRad 2100 dedicated multiphoton LSCM, a Zeiss LSM 7 MP dedicated multiphoton LSCM, a Nikon TIRF (total-internal reflection fluorescence) system, a Nikon/Yokogawa CSU-W1 spinning disk microscopy system, a PTI monochromator system, and a Nikon SMZ-1500 fluorescence stereoscope. Patch-clamp electronics are available for use on most microscope systems, and each system has an integrated perfusion setup.
Proper citation: University of Vermont Larner College of Medicine Microscopy Imaging Center Live Imaging and PhysiologyCore Facility (RRID:SCR_021289) Copy
Provides short training courses to in service public health practitioners and professionals.Offers teaching, research, and policy advice in public health in Pakistan.
Proper citation: Islamabad Health Services Academy Core Facility (RRID:SCR_021209) Copy
https://www.ualberta.ca/medicine/research/corefacilities/autoclave-repair-core.html
Core provides on-site repair and maintenance services for autoclaves and laboratory washers.Core is also responsible, in collaboration with Environment, Health and Safety, for temperature probe calibrations of autoclaves located in FoMD enhanced biocontainment facilities.
Proper citation: University of Alberta Faculty of Medicine and Dentistry Autoclave Repair Core Facility (RRID:SCR_019180) Copy
https://www.ualberta.ca/medicine/research/corefacilities/workshop.html
Core provides services, including repair of lab equipment and biosafety cabinets, metal and acrylic fabrication, woodworking, welding, machining, and calibration of pipets.
Proper citation: University of Alberta Faculty of Medicine and Dentistry Workshop Core Facility (RRID:SCR_019181) Copy
https://www.ualberta.ca/medicine/research/corefacilities/hcacore/index.html
Core houses equipment to manage and automate large-scale experiments in areas such as drug discovery and single cell analysis. From sample processing and liquid handling to quantitative analysis of sequencing, imaging, and fluorescent data, core offers high throughput methods for screening needs.
Proper citation: University of Alberta Faculty of Medicine and Dentistry High Content Analysis Core Facility (RRID:SCR_019182) Copy
https://www.unmc.edu/cctr/resources/biobank/index.html
Nebraska Biobank is made up of residual blood samples from volunteer patients. Serum, Plasma, and DNA are recovered from the consented samples and stored for future research studies.Deidentified data from the Electronic Health Record (EHR) such as age range, diagnosis, and medications are linked to the stored samples. Any faculty member from the University of Nebraska system may request samples from the biobank for their research projects but all requests are subject to feasibility and scientific merit review.Offers sample management services to investigators for clinical trials and registries.
Proper citation: University of Nebraska Medical Center Nebraska Biobank Core Facility (RRID:SCR_021024) Copy
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