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https://www.colorado.edu/lab/massspec/

Offers analytical and instructional expertise in mass spectrometry with practical training and access to instrumentation.Located in room C1B90 of Jennie Smoly Caruthers Biotechnology Building houses six mass spectrometry systems.Instruments are interfaced with chromatographic system in order to separate complex mixture samples. Offers training for open access to some instruments including Thermo ISO LT GCMS, Synapt G2 HDMS, Agilent 6120 LCMS, and 4000 Q-trap QQQ instruments.

Proper citation: Colorado University at Boulder Central Analytical Mass Spectrometry Core Facility (RRID:SCR_018992) Copy   

•   Source: SciCrunch Registry

https://dentistry.musc.edu/research/gcohr

Core offers investigators opportunity to address research questions that require use of gnotobiotic animals. Standard services provide germ free mice (e.g. BALB/c, C57BL/6), deriving new strains of mice into germ free state by caesarean section, tissue collection and/or fluid from mice that have not received treatment or manipulations, exporting germ free mice in sterile transporters to other institutions. Non-Standard Services include maintaining and breeding newly derived germ free mice, administration of specialized diets, administration of compounds as therapeutic or disease-inducing agents, tissue collection and/or fluid from mice that have received treatment or manipulations.

Proper citation: Medical University of South Carolina College of Dental Medicine Gnotobiotic Animal Core Facility (RRID:SCR_018884) Copy   

•   Source: SciCrunch Registry

https://www.unh.edu/research/welcome-university-instrumentation-center

University wide core facility offers NMR,SEM including FIB, EBS, EBSD, Tensile Stage,Confocal,X-Ray Photoelectron Spectroscopy,X-Ray Microscope aka Micro CT, Expert analysis of research and industrial samples,Training in scientific instrument operation and data analysis, Maintenance, repair, and calibration of instruments,Specialty instrument engineering design and application services,Facilitation of access to scientific instruments throughout the university.

Proper citation: University of New Hampshire University Instrumentation Center Core Facility (RRID:SCR_021101) Copy   

•   Source: SciCrunch Registry

https://www.lsi.umich.edu/science/centers-technologies/center-structural-biology

Comprehensive structural biology resource.Provides high throughput protein laboratory for protein engineering, protein purification facilities for small- and large-scale protein production, macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules, and X-ray facility with access to high energy synchrotron radiation. Provides expert guidance to researchers through every stage of project, collaborating and consulting with researchers who use the facilities. Service categories are Chemical, Material and Protein Characterization, Molecular Biology. Services include Cloning, Crystallization, Differential thermal analysis, Drug development, NMR (small molecule), PCR, Protein crystallography, Protein engineering, Protein production, Structure determination, Xray.

Proper citation: University of Michigan Center for Structural Biology Core Facility (RRID:SCR_021065) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/geologicalsciences/resources/research-facilities/raman-microspectroscopy-lab

Core research facility housed in Department of Geological Sciences for fast, non-destructive characterization and chemical imaging of diverse materials spanning minerals (thin sections and powders), biological samples, fluids, dissolved gases, and much more.

Proper citation: University of Colorado Boulder Raman Microspectroscopy Lab Core Facility (RRID:SCR_019305) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/biocore/

Purpose is to connect MCDB, EBIO, and IPHY researchers to campus research resources.

Proper citation: University of Colorado Boulder BioCore Core Facility (RRID:SCR_019302) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/geologicalsciences/resources/research-facilities/u-thhe-thermochronology-lab

Fully equipped (U-Th)/He thermochronology facility.

Proper citation: University of Colorado Boulder CU Thermochronology Research and Instrumentation Lab Core Facility (RRID:SCR_019303) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/geologicalsciences/resources/research-facilities/earth-systems-stable-isotope-laboratory

Designed to measure relative abundance of stable isotopes of light elements and molecules.

Proper citation: University of Colorado Boulder Earth Systems Stable Isotope Lab Core Facility (RRID:SCR_019300) Copy   

•   Source: SciCrunch Registry

https://cami.northwestern.edu/

Provides access to range of preclinical imaging modalities and support services. These include MRI, nuclear imaging (PET, SPECT, and CT), in vivo bioluminescence and fluorescence imaging, animal housing and prep spaces, and tissue culture. Image analysis services are available, as are software packages (JIM, Amira, Matlab) and a workstation for users to perform their own data analysis. Imaging services can be provided for investigators' own animal models, or animal models can be supplied by the Developmental Therapeutics Core.

Proper citation: Northwestern University Center for Advanced Molecular Imaging Core Facility (RRID:SCR_021192) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/zebrafish/

Provides Penn State research community with modern, centralized facility for housing, breeding and performing experiments with zebrafish.Provides physical and intellectual infrastructure for investigators whose research can benefit from use of zebrafish as model system.

Proper citation: Penn State Hershey College of Medicine Zebrafish Functional Genomics Core Facility (RRID:SCR_021199) Copy   

•   Source: SciCrunch Registry

https://www.etsu.edu/com/mbcf/

Core provides Genomics, Transcriptomics and Proteomics Services to researchers.

Proper citation: East Tennessee State University Quillen College of Medicine Molecular Biology Core Facility (RRID:SCR_021106) Copy   

•   Source: SciCrunch Registry

https://www.wadsworth.org/research/cores/alm

Core facility is designed for Imaging living cells or tissues, Fluorescence imaging, Image analysis. Provides imaging of adherent cells or tissue fragments,drug delivery using perfusion chamber, gas exchange for the growth media, Rose chambers for imaging, image processing and analysis software to assist in data analysis and interpretation.

Proper citation: New York State Department of Health Wadsworth Center Advanced Light Microscopy and Image Analysis Core Facility (RRID:SCR_021104) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/nmr/

Core serves research needs of entire campus community as well as outside research entities. Facility maintains a variety of NMR spectrometers at variety of magnetic fields to support research needs.

Proper citation: Colorado University at Boulder Nuclear Magnetic Resonance Spectroscopy Core Facility (RRID:SCR_019311) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/epigenomics-facility

Provides service that maps protein DNA interactions genome wide, tracks experimental metadata, and implements quality controlled data processing and research based analysis pipelines. Provides epigenomic and bioinformatic research resources and services that include sample preparation services and data generation. Open source platforms enable and reinforce FAIR data practices. Core is able to receive and process cell and tissue samples for various diagnostic epigenetic assays.

Proper citation: Cornell University BRC Epigenomics Core Facility (RRID:SCR_021287) Copy   

•   Source: SciCrunch Registry

https://nuance.northwestern.edu/facilities/biocryo/index.html

Provides source for characterization of biological, soft matter, and hybrid samples with TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and STEM (Scanning Transmission Electron Microscopy) at cryogenic or at ambient temperature.Provide expertise and access to equipment for cryofixation and processing of frozen hydrated samples by high pressure freezing, plunge freezing, freeze fracturing, cryo ultramicrotomy, freeze substitution, and turbo freeze-drying. Conventional samples can be processed at ambient temperature with chemical fixation, dehydration, and resin embedding, or critical point drying. Offers EDX (Energy Dispersive X-ray Spectroscopy) for elemental analysis.Offers training on instruments and sample preparation techniques.BioCryo staff mentors new users, advises on experimental design, and collaborates with researchers in experiments with challenging and unconventional samples.BioCryo Facility participates in numerous educational and outreach events, e.g. workshops, seminars, demos, and facility tours.

Proper citation: Northwestern University NUANCE BioCryo Core Facility (RRID:SCR_021288) Copy   

•   Source: SciCrunch Registry

http://web.ncifcrf.gov/atp/default.asp?LabID=12&page=labs

Comprises six service groups. Our services are available to all NIH intramural researchers, and by interagency agreements to FDA and US Army at Ft. Detrick. We are happy to consult and distribute materials to not-for-profit institutions.Clone Optimization service include DNA cloning for protein expression; Gateway-based; fluorescent, epitope, solubility, purification tags; mutagenesis; vectors for insect/ baculovirus, mammalian, E. coli, P. pastoris, K. lactis. Microbial Expression: E. coli, P. pastoris, K. lactis, 2 mL to 60 L, autoinduction and IPTG; fully instrumented fermenters.Eukaryotic Expression service include insect / baculovirus, mammalian transient and stable, monoclonal antibodies.Protein Purification service include parallel microscale for process development; affinity and native, tag and endotoxin removal; scale-up to low gram scale.Virus Technology service include custom and stock adenovirus and lentivirus production; titer determination; promoter and reporter panels in lentivirus ready to deliver.Molecular Detection: qPCR and ELISA assaysdeveloped and executed, focused on human viruses in human samples; qPCR assays for mycoplasma and human pathogenic viruses contaminating cell lines; cell line identity testing.

Proper citation: Frederick National Laboratory Protein Expression Laboratory Core Facility (RRID:SCR_021286) Copy   

•   Source: SciCrunch Registry

https://strucbiol.pbsci.ucsc.edu/

Provides instrumentation, supplies, and expertise to assist researchers in structural characterization of biological macromolecules. Resources are available for crystallization and structure determination as wells as biophysical characterization of macromolecular stability and interactions.

Proper citation: University of California Santa Cruz Macromolecular Structure Function Core Facility (RRID:SCR_021283) Copy   

•   Source: SciCrunch Registry

https://biomedical-sciences.uq.edu.au/facilities/imaging-facilities

Provides microscopes for life science research, including number of confocals, widefield systems, slide scanners, and analysis packages. Provides analytic instruments such as flow cytometers, imaging systems, and PCR equipment among others. Our team consists of experienced biologists and are available to help you with experiment building, troubleshooting, and data analysis.

Proper citation: University of Queensland School of Biomedical Sciences Imaging and Analytics Core Facility (RRID:SCR_019246) Copy   

•   Source: SciCrunch Registry

https://cemas.osu.edu

Centralized, coordinated imaging facility.Provides electron and ion beam analytical microscopy instruments.Full service facility from extensive sample preparation laboratories to image processing tools and support.

Proper citation: Ohio State University Center for Electron Microscopy and Analysis Core Facility (RRID:SCR_021294) Copy   

•   Source: SciCrunch Registry

https://mcgill.ca/cftrc/platforms/primary-airway-cell-biobank-pacb

Nonprofit facility providing researchers worldwide with standardized, high-quality primary airway cells from normal and large variety of airway diseased donors with different genetic backgrounds, are essential for improving our understanding of CF and other respiratory diseases and for translational research to develop new therapeutic agents.The PACB is certified by the UBC Office of Biobank Education and Research Biobank Certification Program.

Proper citation: McGill University Primary Airway Cell Biobank Core Facility (RRID:SCR_020998) Copy   

•   Source: SciCrunch Registry