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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://azurebiosystems.com/azure-600/
System offers two channel, laser based IR and chemiluminescent detection, with speed and sensitivity of film, with ability to image visible fluorescent dyes, standard EtBr and protein gels, and infrared laser excitation for quantitative Western blot imaging in NIR.
Proper citation: Azure Biosystems: 600 Western Blot Imaging System (RRID:SCR_023780) Copy
http://www.waksman.rutgers.edu/genomics/home
Equipped with NextSeq500, MiSeq, and Ion Proton performs de novo genome sequencing, genome resequencing, ChIP-Seq and RNA-seq. Performs library construction, template preparation and sequencing of libraries or provides training in library preparation methods.Performs procedures to enrich or remove polyadenylated RNA, rRNA and/or tRNA as needed. Provides bioinformatics support for projects,data management and analysis plan before selecting samples and initiating data collection.
Proper citation: Rutgers University Waksman Institute of Microbiology Genomics Core Facility (RRID:SCR_011042) Copy
https://www.urmc.rochester.edu/research/rochester-genomics-center.aspx
Provides core laboratory support, technical consultation, assistance with experimental design and data analysis for investigators using high throughput genomic sequencing, genotyping and gene expression in their research programs.Provides support for RNA-Seq, ATAC-seq, ChIP-Seq, Single Cell RNA-seq, Spatial Transcriptomics, Exome/Genome sequencing, Whole Genome and Reduced Representation Bisulfite Sequencing (WGBS, RRBS), 16S rRNA Sequencing, Small RNA-Seq, Metatranscriptomics, qRT-PCR, processing of RNA/DNA, as well as custom applications and approaches. Bioinformatic analysis support is also available.
Proper citation: University of Rochester Genomics Research Center Core Facility (RRID:SCR_012359) Copy
http://www.montana.edu/massspec/index.html
Provides access to mass spectrometers and mass spectrometry expertise. The facility currently maintains the following equipment Waters Synapt-XS Q-IMS-TOF with Waters I-Class UHPLC; Agilent 6538 Q-TOF with Agilent 1290 UHPLC;Agilent 7800 Inductively Coupled Plasma with Laser Ablation (193 nm);Bruker micrOTOF with Agilent 1290 UHPLC; Agilent 6490 Triple Quadrupole Mass Spectrometer; Bruker MALDI Autoflex; Agilent GC-MS; Waters Synapt G2S-i Q-TOF with Ion Mobility.
Proper citation: Montana State University Mass Spectrometry Core Facility (RRID:SCR_012482) Copy
https://www.urmc.rochester.edu/research/flow-core.aspx
Provides investigators with instrumentation along with expertise. Core instrumentation includes traditional analytical cytometers, full spectrum cytometer, cell sorters, imaging cytometers, small(nano) particle detection system, metabolomics instrument, and mass cytometer.
Proper citation: University of Rochester Medical Center Flow Cytometry Core Facility (RRID:SCR_012360) Copy
https://www.urmc.rochester.edu/research/electron-microscope.aspx
Electron Microscopy Resource supports ultra-structural interrogation of tissues, biologic solutions and nanomaterials for investigators utilizing transmission electron microscopy (TEM), scanning electron microscopy (SEM) and cryo-TEM.
Proper citation: University of Rochester Medical Center Electron Microscopy Core Facility (RRID:SCR_012366) Copy
Core provides molecular biotechnology services and current molecular genetic methods. Services include DNA and RNA Extraction, transgenic mouse genotyping, Human Cell line Authentication, Sanger DNA Sequencing, Next-Generation sequencing platforms, Microsatellite DNA Typing, Agena multiplex SNP Genotyping, Real-time PCR, NanoString Gene Expression Analysis. Specializes in custom workflows that couple services with specific research needs.
Proper citation: Arizona Genetics Core (RRID:SCR_012429) Copy
http://www.ohri.ca/stemcore/Default.aspx
StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.
Proper citation: Ottawa Hospital Research Institute StemCore Laboratories Core Facility (RRID:SCR_012601) Copy
https://www.salk.edu/science/core-facilities/integrative-genomics-and-bioinformatics-core/
Core houses state-of-the-art equipment in sequencing and genomics, including high-throughput sequencing systems such as Illumina NovaSeq 6000, NextSeq 2000, MiniSeq, and PacBio Sequel IIe system (long-read sequencing), as well as 10x Genomics Chromium Controller single-cell solution, NanoString nCounter MAX Analyzer, and GeoMx Digital Spatial Profiler instrument, along with QuantStudio Real-Time PCR instruments.
Proper citation: Salk Institute Next Generation Sequencing Core (NGS) (RRID:SCR_014846) Copy
Core mass spec and proteomic services include open access lab for trained users with GC/MS, LC/MS, high resolution LC/MS, and MALDI-TOF instruments, help with intact protein analysis, targeted quantitation, drug discovery support, pathway analysis, protein interactions, FFPE tissue analysis, both labeled and label-free proteomics, and more. Please contact SUMS to discuss these and other custom projects including new application development.
Proper citation: Stanford University Vincent Coates Foundation Mass Spectrometry Laboratory Core Facility (RRID:SCR_017801) Copy
https://sites.northwestern.edu/nucapt/
Facility specializes in high resolution chemical imaging by three dimensional atom probe tomography. APT produces three-dimensional (3D) atom-by-atom elementally and isotopically resolved image with sub-nanometer spatial resolution of sample volume typically 100 x 100 x 300 nm^3, by simultaneous high resolution direct-space imaging and atom-by-atom time of flight mass spectrometry. APT is particularly suited to study nano- or nanostructured materials.
Proper citation: Northwestern University Center for Atom Probe Tomography Core Facility (RRID:SCR_017770) Copy
https://geiselmed.dartmouth.edu/dartmouse/
Core dedicated to facilitation and development of congenic mice for pre clinical projects across United States. Provides genotyping, background checks to verify purity of mice DNA.
Proper citation: Darthmouth Geisel School of Medicine DartMouse Core Facility (RRID:SCR_017756) Copy
http://www.ucdmc.ucdavis.edu/cancer/research/sharedresources/flowcytometry.html
Core provides access to expertise and instrumentation for analytical flow cytometry, cell sorting and laser scanning cytometry.Cell sorting and analytical cytometers are located at three sites in Davis and Sacramento for research use on recharge basis. Provides cell sorters for assisted sorting on appointment basis and provides training to investigators in acquiring data on analytic cytometers.Can advise on experiment design for flow cytometry, provides training to enable independent use of analytical cytometers, and familiarize investigators with popular data analysis software tools such as BD Diva and CellQuest, FlowJo, ModFit and iBrowser.
Proper citation: University of California Davis Flow Cytometry Shared Resource Laboratory Core Facility (RRID:SCR_017826) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/proteomics-laboratory
Core offers specialized expertise for analysis of proteins and peptides using mass spectrometry. Develops new methods and customized approaches for proteomic analysis and suggests experimental strategies and sample preparation prior to mass spectrometry analysis. Services include:comprehensive protein identification ,analysis of affinity purified complexes,characterizing protein post-translational modifications,de novo sequencing,label and label-free quantitation ,multiplexed quantitation global phosphorylation and ubiquitin analysis,analysis of laser-capture microdissected formalin-fixed paraffin-embedded tissue,secretome analysis,crosslinking analysis,disulfide mapping.
Proper citation: New York University School of Medicine Langone Health Proteomics Laboratory Core Facility (RRID:SCR_017926) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/genome-technology-center
Core provides range of services related to genome, epigenome, and transcriptome analysis. Offers technologies including Illumina deep sequencing and sample preparation for variety of applications, including DNA and RNA sequencing (DNA- and RNA-seq), exome sequencing, targeted capture, chromatin immunoprecipitation sequencing (ChIP-seq), methylation sequencing (Methyl-seq), metagenomics, and many others;Automation of Illumina library and targeted capture preps, including 16S ribosomal RNA (rRNA) sequencing;Oxford Nanopore sequencing (long reads);Bio-Rad Droplet Digita polymerase chain reaction (PCR);Nanostring nCounter;Single-cell RNA- and DNA-seq using the C1 Auto Prep System from Fluidigm, and 10x Genomics Chromium System.Provides expertise on strategies to achieve research goals in any field related to genomics, and can tailor bioinformatics analysis to individual project. If you supply us with nucleic acids, we can perform every step required to help you achieve your desired results.
Proper citation: New York University School of Medicine Langone Health Genome Technology Center Core Facility (RRID:SCR_017929) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/genotyping-core-laboratory
Core provides fast, accurate, convenient, and affordable genotyping technologies. We use conventional polymerase chain reaction (PCR) and gel electrophoresis methods. By pooling samples from group of users, we can better ensure accuracy, cost-effectiveness, and quality control.
Proper citation: New York University School of Medicine Langone Health Genotyping Core Laboratory Core Facility (RRID:SCR_017932) Copy
Core mission is to drive scientific discovery through use of human specimens.Helps facilitate translational research, match human specimen resources to scientific needs, foster multi-investigator collaborative projects, and catalyze scientific innovation,improving researcher access to existing biospecimen resources, and enhancing institution-wide tissue-banking efforts and capacity. Another priority is to implement campus-wide policy for human biospecimen collection and storage to ensure regulatory compliance.
Proper citation: New York University School of Medicine Langone Health Center for Biospecimen Research and Development Core Facility (RRID:SCR_017930) Copy
http://www.mayo.edu/research/core-resources/immunochemical-core/overview
Provides immunochemical, chemistry and immune testing to clinical and basic science researchers, develops and validates new assays, and improves current assay methodology. Services include Assay development, Automated chemistry analysis, Immunoassay analysis, Small molecule analysis,Mass Spectrometry, LC-MS/MS and HRAM LC-MS,Enzyme-linked immunosorbent (ELISA), Meso Scale Discovery (MSD), Luminex, and radioimmunoassay (RIA) procedures for various analytes.
Proper citation: Mayo Clinic Immunochemical Core Facility (RRID:SCR_017867) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/microscopy-laboratory
Core offers comprehensive light and electron microscopy technologies. Our scientists use light microscopes and electron microscopes at resolutions ranging from centimeters to angstroms, providing clear and detailed images.We assist at every stage of your experiment, offering research-design consultation and instrument training, as well as guidance in study execution, analysis, and presentation for publication.
Proper citation: New York University School of Medicine Langone Health Microscopy Laboratory Core Facility (RRID:SCR_017934) Copy
Core provides statistical and big data analysis support. Performs data analysis and manuscript preparation services in Biostatistics, such as statistical genetics, longitudinal, survival, and high-throughput/high-dimensional omics data analysis; and Bioinformatics, such as DNA- and RNA-seq alignment, single cell DNA- and RNA-seq analysis, variant calling, differential expression and pathway analysis, data integration, online data submission, and custom script writing. Provides training to lab staff to enable them to perform future analyses.
Proper citation: Oregon Health and Science University Bioinformatics and Biostatistics Core Facility (RRID:SCR_017946) Copy
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