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Species: Synthetic
Genetic Insert: SH2
Vector Backbone Description: Vector Backbone:pCMV-N1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:37945909
Comments: Please visit https://doi.org/10.1101/2023.03.28.534597 for bioRxiv preprint.
Proper citation: RRID:Addgene_209704 Copy
Species: Synthetic
Genetic Insert: HRas (G12V)
Vector Backbone Description: Vector Backbone:pCMV-N1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:37945909
Comments: Please visit https://doi.org/10.1101/2023.03.28.534597 for bioRxiv preprint.
Proper citation: RRID:Addgene_209705 Copy
Species: Mus musculus
Genetic Insert: ActB
Vector Backbone Description: Vector Backbone:pS23.U6; Vector Types:Mouse Targeting, CRISPR; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37713292
Comments: Please visit https://doi.org/10.1101/2020.07.15.199620 for bioRxiv preprint.
Proper citation: RRID:Addgene_207408 Copy
Species: Synthetic
Genetic Insert: EGFP/BC29
Vector Backbone Description: Vector Backbone:pCER206; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37321219
Proper citation: RRID:Addgene_202870 Copy
Species: Synthetic
Genetic Insert: EGFP/BC30
Vector Backbone Description: Vector Backbone:pCER206; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37321219
Proper citation: RRID:Addgene_202871 Copy
Species: Synthetic
Genetic Insert: Cox4-NbGFP_miRFP670nano3
Vector Backbone Description: Vector Backbone:pCMV-N1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:37945909
Comments: Please visit https://doi.org/10.1101/2023.03.28.534597 for bioRxiv preprint.
Proper citation: RRID:Addgene_209719 Copy
Species: Synthetic
Genetic Insert: PRLSS-SH2-KDEL
Vector Backbone Description: Vector Backbone:pCMV-N1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:37945909
Comments: Please visit https://doi.org/10.1101/2023.03.28.534597 for bioRxiv preprint.
Proper citation: RRID:Addgene_209716 Copy
Species: Synthetic
Genetic Insert: WDR5-P2A-SH2-P2A-Ras-CAAX
Vector Backbone Description: Vector Backbone:pCMV-N1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:37945909
Comments: Please visit https://doi.org/10.1101/2023.03.28.534597 for bioRxiv preprint.
Proper citation: RRID:Addgene_209712 Copy
Species: Synthetic
Genetic Insert: NLS-MBP-rATOM(WDR5)
Vector Backbone Description: Vector Backbone:pCMV-N1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:37945909
Comments: Please visit https://doi.org/10.1101/2023.03.28.534597 for bioRxiv preprint.
Proper citation: RRID:Addgene_209710 Copy
Species: Homo sapiens
Genetic Insert: OPRK1
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5400; Vector Backbone:pcDNA3.0; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Proper citation: RRID:Addgene_208918 Copy
Species: Synthetic
Genetic Insert: mCherry
Vector Backbone Description: Vector Backbone:BattB; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37922210
Proper citation: RRID:Addgene_200633 Copy
Species: Homo sapiens
Genetic Insert: PTEN
Vector Backbone Description: Vector Backbone:BattB; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37922210
Proper citation: RRID:Addgene_200634 Copy
Species: Human immunodeficiency virus
Genetic Insert: Vif
Vector Backbone Description: Vector Backbone:BattB; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37922210
Proper citation: RRID:Addgene_200637 Copy
Species: Homo sapiens
Genetic Insert: 3xHA-LTB4R(S310A)
Vector Backbone Description: Vector Backbone:pLenti 2nd gen; Vector Types:Mammalian Expression, Lentiviral; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37788324
Comments: 5' Cloning Site: BamHI (not destroyed); 3' Cloning Site: NotI (not destroyed)
Proper citation: RRID:Addgene_208093 Copy
Species: Homo sapiens
Genetic Insert: Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like 3B
Vector Backbone Description: Backbone Size:8007; Vector Backbone:BE4max; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37672599
Comments: Additional important insert: Cas9n-UGI-UGI-NLS
Please note: Plasmid contains an E198K mutation in Cas9. This mutation is not known to affect plasmid function.
Proper citation: RRID:Addgene_207167 Copy
Species: Homo sapiens
Genetic Insert: Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like 3A
Vector Backbone Description: Backbone Size:8006; Vector Backbone:BE4max; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:37672599
Comments: Please note: Plasmid contains an E198K mutation in Cas9. This mutation is not known to affect plasmid function.
Proper citation: RRID:Addgene_207166 Copy
Species: Homo sapiens
Genetic Insert: hMDH1v3
Vector Backbone Description: Backbone Marker:Novagen; Backbone Size:5206; Vector Backbone:pET28a; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Comments: UniProt ID: https://www.uniprot.org/uniprotkb/P40925/entry#P40925-2
Please note: The Uniprot page includes information for all three transcripts. This MDH transcript variant is NOT considered the canonical isoform. See MDH variant alignment map for details.
For more information, please see the MDH CUREs Community website: https://www.mdhcures.org/.
Proper citation: RRID:Addgene_204229 Copy
Species: Aquaspirillum arcticum
Genetic Insert: MDH_AQUAR
Vector Backbone Description: Backbone Marker:Novagen; Backbone Size:5211; Vector Backbone:pET24a; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Comments: UniProt ID: https://www.uniprot.org/uniprotkb/Q9ZF99/.
Bacterium isolated from under snow and ice, in the northwest territory of Canada. The sequence of this MDH is highly related to thermophilic MDH. This protein is 2-3-fold more active at 4-10 °C than other MDH enzymes – possibly due to an increased flexibility at the active site as well as reduced interactions at subunits.
For more information, please see the MDH CUREs Community website: https://www.mdhcures.org/.
Proper citation: RRID:Addgene_204239 Copy
Species: Arabidopsis thaliana
Genetic Insert: MDHNP_ARATH
Vector Backbone Description: Backbone Marker:Novagen; Backbone Size:5268; Vector Backbone:pET24a; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Comments: UniProt ID: https://www.uniprot.org/uniprotkb/Q8H1E2/.
Plays an essential role in the regulation of catalase activity and the accumulation of a hydrogen peroxide-dependent signal by transmitting the redox state of the chloroplast to other cell compartments.
For more information, please see the MDH CUREs Community website: https://www.mdhcures.org/
Proper citation: RRID:Addgene_204238 Copy
Species: Saccharomyces cerevisiae
Genetic Insert: MDHM_YEAST
Vector Backbone Description: Backbone Marker:Novagen; Backbone Size:5320; Vector Backbone:pET28a; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Comments: UniProt ID: https://www.uniprot.org/uniprotkb/P17505/.
Expression changes based on metabolite starting point. Involvement of MDH in the asp-malate shuttle in yeast extends replicative lifespan and may play a role in calorie-restricted life extension.
For more information, please see the MDH CUREs Community website: https://www.mdhcures.org/.
Proper citation: RRID:Addgene_204231 Copy
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