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Grant Mccallum, Nathan Kostick, Joseph Marmerstein, Yang Zheng, Dominique Durand 2021. Glossopharyngeal Nerve Chronic Recording In Anesthetized Rat. protocols.io https://dx.doi.org/10.17504/protocols.io.wssfeeeCopy Citation Copied
URL: https://dx.doi.org/DOI:10.17504/protocols.io.wssfeee
Authors: Grant Mccallum, Nathan Kostick, Joseph Marmerstein, Yang Zheng, Dominique Durand
Group: SPARC
Summary: We propose to develop a neural interface based on carbon nanotube (CNT) yarns with a size similar to large axons (10 µm) that has a mechanical and molecular compatibility with the nerve. The mechanical properties of the interface will be optimized by matching flexural rigidity of the implant to that of the glossopharyngeal nerve (GLN). Since the wire is very flexible, a custom-inserting technique has been developed for this purpose and tested in rats. Following insertion, the signal-to-noise ratio and impedance of the wires will be measured for 3 months. The biocompatibility of the implant will be assessed using histological techniques.
Affiliations: Case Western Reserve University, Case Western Reserve University, Case Western Reserve University, Case Western Reserve University, Case Western Reserve University
Version: 1
Publication Date: 2021
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