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Protocol Name
DOI:DOI:10.17504/protocols.io.rtzd6p6 RRID Copied  
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Fan Zhang, Jessica Weckhorst, Adrien Assie, Anastasia Khodakova, Mario Loeza Cabrera, Daniela Vidal, Christopher Ayoub, Buck Samuel 2020. High-throughput assessment of changes in the Caenorhabditis elegans gut microbiome. protocols.io https://dx.doi.org/10.17504/protocols.io.rtzd6p6
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Protocol Information

URL: https://dx.doi.org/DOI:10.17504/protocols.io.rtzd6p6

Authors: Fan Zhang, Jessica Weckhorst, Adrien Assie, Anastasia Khodakova, Mario Loeza Cabrera, Daniela Vidal, Christopher Ayoub, Buck Samuel

Summary: The gut microbiome is an important driver of host physiology and development. Altered abundance or membership of this microbe community can influence host health and disease progression, including the determination of host lifespan and healthspan. Here, we describe a robust pipeline to measure the microbiome abundance and composition in the C. elegans gut that can be applied to examine the role of the microbiome on host aging processes.

Associated Publications: Dirksen P, Assié A, Zimmermann J, Zhang F, Tietje A, Marsh SA, Félix M, Shapira M, Kaleta C, Schulenburg H, Samuel BS, CeMbio - The Microbiome Resource. G3: Genes|Genomes|Genetics 10(9). doi: 10.1534/g3.120.401309

Affiliations: Baylor College of Medicine, Baylor College of Medicine, Baylor College of Medicine, Baylor College of Medicine, Baylor College of Medicine, Baylor College of Medicine, Baylor College of Medicine, Baylor College of Medicine

External URL: https://doi.org/10.1534/g3.120.401309

Version: 1

Publication Date: 2020

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