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Marita A. Isokallio, James Stewart 2018. Low-frequency variant calling from high-quality mtDNA sequencing data. protocols.io https://dx.doi.org/10.17504/protocols.io.nfkdbkwCopy Citation Copied
URL: https://dx.doi.org/DOI:10.17504/protocols.io.nfkdbkw
Authors: Marita A. Isokallio, James Stewart
Group: Stewart-Lab MPI-AGE
Summary: High-quality, highly enriched mitochondrial DNA (mtDNA) sample enables detection of extremely low-frequency mtDNA variants. When mtDNA is carefully enriched, fragmented in the presence of EDTA and sequenced with unique dual indices by Illumina HiSeq in paired-end mode, it is possible to reliably detect variants at allele frequencies
Affiliations: Max Planck Instutute for Biology of Ageing, Max Planck Instutute for Biology of Ageing
Version: 1
Publication Date: 2018
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