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URL: https://dx.doi.org/DOI:10.17504/protocols.io.ki6cuhe

Authors: Sven Van Poucke, Dana Huskens, Kurt Van der Speeten, Mark Roest, Bart Lauwereins, Ming-Hua Zheng, Seppe Dehaene, Joris Penders, Abraham Marcus, Marcus Lancé

Group: HIPACAT

Summary: Standard hematological analyses EDTA-anticoagulated blood was used for cytometric analysis using a whole blood counter Sysmex XE 2100® (Sysmex,Kobe, Japan) to obtain a whole blood count. Fibrinogen levels were determined with an ACL-9000 (Diamond Diagnostics, Holliston, MA) coagulation analyser, using a PT-fibrinogen high sensitivity reagent, which is a high-sensitivity calcium thromboplastin that allows the simultaneous determination of PT and fibrinogen levels. aPTT was measured using an ACL-9000 coagulation analyser and INR was calculated by the formula INR (PT patient/PT normal).

Associated Publications: Poucke SV, Huskens D, Speeten KVd, Roest M, Lauwereins B, Zheng M, Dehaene S, Penders J, Marcus A, Lancé M (2018) Thrombin generation and platelet activation in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy - A prospective cohort study. PLoS ONE 13(6): e0193657. doi: 10.1371/journal.pone.0193657

Affiliations: Department of Anesthesiology, Intensive Care, Emergency Medicine and Pain Therapy, ZOL, Genk, Belgium, Synapse Research Institute, Maastricht, The Netherlands., Department of Surgery, ZOL, Genk, Belgium., Synapse Research Institute, Maastricht, The Netherlands., Department of Anesthesiology, Intensive Care, Emergency Medicine and Pain Therapy, ZOL, Genk, Belgium., Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China., Department of Anesthesiology, Intensive Care, Emergency Medicine and Pain Therapy, ZOL, Genk, Belgium., Central Diagnostic Laboratory,ZOL, Genk, Belgium., Department of Anesthesiology, ICU and Perioperative Medicine,HMC, Doha,Qatar., Department of Anesthesiology, ICU and Perioperative Medicine,HMC, Doha,Qatar.

External URL: https://doi.org/10.1371/journal.pone.0193657

Version: 1

Publication Date: 2017

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