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Bonnie Hurwitz 2015. Finding the core vs flexible microbiome. protocols.io https://dx.doi.org/10.17504/protocols.io.d2y8fvCopy Citation Copied
URL: https://dx.doi.org/DOI:10.17504/protocols.io.d2y8fv
Authors: Bonnie Hurwitz
Group: Hurwitz Lab, ABE487_HMP, ABE487_EMP
Summary: In a study comparing obese versus lean twins, Turnbaugh and colleagues found that there were "shared microbial genes among sampled individuals, comprising an extensive, identifiable 'core microbiome' at the gene, rather than at the organismal lineage level". This means that despite having differences in bacterial composition, the "core" functional repertoire of microbiome remains the same in obese versus lean twins. In this tutorial, we are going to explore these functional differences in two lean twins (TS1 and TS2) and two obese twins (TS19 and TS20) from this study. Turnbaugh, Peter J., et al. "A core gut microbiome in obese and lean twins."nature 457.7228 (2009): 480-484.
Affiliations: University of Arizona
Version: 1
Publication Date: 2015
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