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Protocol Name
U Mass - Transverse Aortic Constriction
DOI:DOI:10.17504/protocols.io.56ig9ce RRID Copied  
PDF Report How to cite
Mark Kelly, Timothy P. Fitzgibbons 2019. U Mass - Transverse Aortic Constriction. protocols.io https://dx.doi.org/10.17504/protocols.io.56ig9ce
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Protocol Information

URL: https://dx.doi.org/DOI:10.17504/protocols.io.56ig9ce

Authors: Mark Kelly, Timothy P. Fitzgibbons

Group: Mouse Metabolic Phenotyping Centers

Summary: Summary: This is a Mouse model of Transverse aortic constriction (TAC). A commonly used experimental model for pressure overload-induced cardiac hypertrophy and heart failure. Initially leading to compensated hypertrophy of the heart, which often is associated with a temporary enhancement of cardiac contractility. Resulting in cardiac dilatation and heart failure.

Affiliations: University of Massachusetts Medical School, University of Massachusetts Medical School

External URL: https://mmpc.org/shared/document.aspx?id=326&docType=Protocol

Version: 2

Publication Date: 2019

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