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URL: https://dx.doi.org/DOI:10.17504/protocols.io.ix7cfrn

Authors: Alan Daugherty, Jing Liu, Hong Lu

Group: Sangderk Lee lab

Summary: Suprarenal region of the abdominal aorta is the portion from the last intercostal artery to the right renal artery.In the Angiotensin II infused mouse model, abdominal aortic aneurysms are located in this region. Maximal outer width of the suprarenal aorta is a major parameter to define abdominal aortic aneurysms. Fifty % or more increase of this parameter, compared to control (saline infusion), is defined as an abdominal aortic aneurysm.

Associated Publications: Kim S, Yang L, Kim S, Lee RG, Graham MJ, Berliner JA, Lusis AJ, Cai L, Temel RE, Rateri DL, Lee S (2017) Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development. PLoS ONE 12(8): e0182566. doi: 10.1371/journal.pone.0182566

Affiliations: , ,

External URL: https://doi.org/10.1371/journal.pone.0182566

Version: 1

Publication Date: 2017

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