Searching the RRID Resource Information Network
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629006509
Proper Citation: RRID:RRRC_01051
Description: Rattus norvegicus with name SD-Tg(Thy1-APPD)BWevn from RGD.
Species: Rattus norvegicus
Notes: These rats produce human familial CAA Dutch E22Q mutant amyloid APPB2-protein in brain and develop arteriolar CAA type-2. The deposition of fibrillar APPB2 promotes arteriolar smooth muscle cell loss and cerebral microhemorrhages that can be detected by magnetic resonance imaging and confirmed by histopathology. Random integration of a transgene consisting of 2.1 kb of human APP (isoform 770) cDNA carrying the Dutch E693Q mutation cloned between exons II and IV of a Thy1.2 expression cassette. This leads to expression of chimeric mutant human A beta PP under control of the neuronal specific Thy1.2 promoter. The integration site of the transgene is unknown. Rat Resource and Research Center
Expand AllWe found {{ ctrl2.mentions.all_count }} mentions in open access literature.
We have not found any literature mentions for this resource.
We are searching literature mentions for this resource.
Most recent articles:
{{ mention._source.dc.creators[0].familyName }} {{ mention._source.dc.creators[0].initials }}, et al. ({{ mention._source.dc.publicationYear }}) {{ mention._source.dc.title }} {{ mention._source.dc.publishers[0].name }}, {{ mention._source.dc.publishers[0].volume }}({{ mention._source.dc.publishers[0].issue }}), {{ mention._source.dc.publishers[0].pagination }}. (PMID:{{ mention._id.replace('PMID:', '') }})
Check
for resource mentions.
A list of researchers who have used the resource and an author search tool
A list of researchers who have used the resource and an author search tool. This is available for resources that have literature mentions.
No rating or validation information has been found for SD-Tg(Thy1-APPD)BWevn .
No alerts have been found for SD-Tg(Thy1-APPD)BWevn .
Source: Rat Resource and Research Center (RRID:SCR_002044)
Description: Supplies biomedical investigators with rat models, embryonic stem cells, related reagents, and protocols they require for their research. In addition to repository, cryostorage and distribution functions, RRRC can facilitate acquisition of rat strains from other international repositories as well as provide consultation and technical training to investigators using rat models.
URL: http://www.rrrc.us/
Source Database: Rat Resource and Research Center (RRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
Email: info_at_ dknet.org
