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URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150520182
Proper Citation: RRID:RRRC_00938
Description: Rattus norvegicus with name LE-ROSA26em1(CAG-tdTomato)Rrrc from RGD.
Species: Rattus norvegicus
Notes: The DNA construct was made by replacing ZsGreen with TdTomato in plasmid pCAG-loxP-STOP-loxP-ZsGreen (Addgene plasmid #51269, donated by Pawel Pelczar). CRISPR/Cas9 genome editing technology was used to knock in the DNA construct into the rat ROSA26 locus in the embryos from outbred BluHsd:LE. Reporter line that can be crossed with Cre-expressing strains. In presence of Cre, the floxed "STOP" upstream of the TdTomato gene is deleted allowing expression of the red fluorescent TdTomato protein. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center
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Source: Rat Resource and Research Center (RRID:SCR_002044)
Description: Supplies biomedical investigators with rat models, embryonic stem cells, related reagents, and protocols they require for their research. In addition to repository, cryostorage and distribution functions, RRRC can facilitate acquisition of rat strains from other international repositories as well as provide consultation and technical training to investigators using rat models.
URL: http://www.rrrc.us/
Source Database: Rat Resource and Research Center (RRRC)
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