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URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245521
Proper Citation: RRID:RRRC_00634
Description: Rattus norvegicus with name SD-Tg(Th-SNCA*)3Ins from RGD.
Species: Rattus norvegicus
Notes: the transgene overexpressing double-mutated human alpha-synuclein (A53T and A30P) under the control of rat tyrosine hydroxylase (Th)promoter was microinjected into SD ovocytes to generate 3 transgenic rat lines. The MA3 line has pre-symptomatic olfactory deficits (beginning at 6 months of age) and motor deficits starting at a later age (19 months of age). Rat Resource and Research Center
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Source: Rat Resource and Research Center (RRID:SCR_002044)
Description: Supplies biomedical investigators with rat models, embryonic stem cells, related reagents, and protocols they require for their research. In addition to repository, cryostorage and distribution functions, RRRC can facilitate acquisition of rat strains from other international repositories as well as provide consultation and technical training to investigators using rat models.
URL: http://www.rrrc.us/
Source Database: Rat Resource and Research Center (RRRC)