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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=45073130
Proper Citation: RRID:RGD_45073130
Description: Rattus norvegicus with name SD-Fmr1em1Mzhe from RGD.
Species: Rattus norvegicus
Notes: The CRISPR/Cas9 system was used to introduce deletions/mutations in exon 4 of the rat Fmr1 gene of outbred Sprague- Dawley embryos. The resulting mutation is a deletion of five amino acids and a G-A mutation in the Fmr1 gene. This genetic modification results in a frame-shift starting from the second Agenet-like 2 domain in the Fmr1 protein.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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