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Proper Citation: RRID:MGI:4415351
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased interleukin-21 secretion, abnormal spleen morphology, decreased spleen germinal center number, decreased CD4-positive, alpha beta T cell number, abnormal class switch recombination, abnormal B cell physiology, abnormal B cell selection, small Peyer's patches, abnormal Peyer's patch germinal center morphology, decreased IgG1 level, decreased IgG2b level, abnormal B cell number, decreased IgG2c level, decreased IgA level, decreased interleukin-4 secretion, abnormal immune system physiology
Affected Gene: Icos
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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