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Proper Citation: RRID:MGI:3776781
Description: Allele Detail: Spontaneous This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Spontaneous This is a legacy resource.
Phenotype: asthenozoospermia, glomerulosclerosis, pale kidney, abnormal mitochondrial ATP synthesis coupled electron transport, dilated renal tubules, enlarged kidney, abnormal sperm midpiece morphology, oligozoospermia, myopathy, abnormal sperm nucleus morphology, absent sperm head, male infertility, kidney failure, impaired hearing, increased pancreatic beta cell number, abnormal mitochondrial ATP synthesis coupled electron transport, decreased circulating glucose level, increased circulating insulin level, increased insulin secretion, increased pancreatic alpha cell number, pancreatic islet hyperplasia, abnormal mitochondrial ATP synthesis coupled electron transport, decreased litter size, decreased body weight, deafness, arrest of male meiosis, teratozoospermia, lactic acidosis, heart block, decreased germ cell number, reduced male mating frequency, dilated mitochondria, abnormal mitochondrial crista morphology, abnormal mitochondrial ATP synthesis coupled electron transport, dilated proximal convoluted tubules, increased blood urea nitrogen level, premature death, dilated distal convoluted tubules, decreased body weight, abnormal mitochondrial ATP synthesis coupled electron transport, enlarged kidney, increased circulating lactate level, abnormal postnatal growth
Affected Gene: Del(MTmt-Tk-mt-Nd5)1Jiha
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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