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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=626168271
Proper Citation: RRID:RGD_626168271
Description: Rattus norvegicus with name SD-Dp(Sult1a1-Spn)/YahIcsOrl from RGD.
Species: Rattus norvegicus
Notes: Sprague Dawley rat. Tandem duplication of the genetic interval between Sult1a1 and Spn genes using CRISPR/Cas9 engineering. We targeted the genetic interval borders from one allele and the CRISPR/Cas9 system allowed us to cut and transpose those sequences to the same locus on the second allele. Heterozygous animals are Overweight and hypoactivity. European Mouse Mutant Archive(EMMA)
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Source: Rat Genome Database (RGD) (RRID:SCR_006444)
Description: Database for genetic, genomic, phenotype, and disease data generated from rat research. Centralized database that collects, manages, and distributes data generated from rat genetic and genomic research and makes these data available to scientific community. Curation of mapped positions for quantitative trait loci, known mutations and other phenotypic data is provided. Facilitates investigators research efforts by providing tools to search, mine, and analyze this data. Strain reports include description of strain origin, disease, phenotype, genetics, immunology, behavior with links to related genes, QTLs, sub-strains, and strain sources.
URL: http://rgd.mcw.edu
Source Database: Rat Genome Database (RGD)