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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154598
Proper Citation: RRID:RGD_598154598
Description: Rattus norvegicus with name F344.W-np/Shi from RGD.
Species: Rattus norvegicus
Notes: In 1983, Wistar rats with pleural and ascites effusions and severe skin oedema were found at the Shionogi Pharmaceutical Co. The rats were named Nephrose Shionogi (NPS) because they showed nephrosis (F12). Breeding revealed that this phenotype was dominated by a autosomal recessive gene, np. NPS rats develop nephrosis at 4 weeks of age and die within 2 weeks. To prolong survival, NPS rats (np/+) were backcrossed with F344/Shi rats to generate the congenic strain (N12-13). National BioResource Project for the Rat in Japan
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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