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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=407450414
Proper Citation: RRID:RGD_407450414
Description: Rattus norvegicus with name SD-Il6em1Yona+/+ from RGD.
Species: Rattus norvegicus
Notes: The wild type rats were littermates of cross of heterozygous Il6 mutant rats. The wild type littermates were used as experimental controls for the homozygous mutant SD-Il6em1Yona-/- (RGD:407450413) generated using the CRISPR/Cas9 technique to induce a 118 bp deletion in the reading frame of the second exon of Il6 by KAC Co. Ltd (Kyoto, Japan). National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka 564-8565, Japan
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Source: Rat Genome Database (RGD) (RRID:SCR_006444)
Description: Database for genetic, genomic, phenotype, and disease data generated from rat research. Centralized database that collects, manages, and distributes data generated from rat genetic and genomic research and makes these data available to scientific community. Curation of mapped positions for quantitative trait loci, known mutations and other phenotypic data is provided. Facilitates investigators research efforts by providing tools to search, mine, and analyze this data. Strain reports include description of strain origin, disease, phenotype, genetics, immunology, behavior with links to related genes, QTLs, sub-strains, and strain sources.
URL: http://rgd.mcw.edu
Source Database: Rat Genome Database (RGD)