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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=288084582
Proper Citation: RRID:RGD_288084582
Description: Rattus norvegicus with name F344-Txn1 em1Kyo from RGD.
Species: Rattus norvegicus
Notes: This CRISPR/Cas9 induced mutation Phe54Leu is induced in embryos of F344/NSlc. The genome editing system targeting exon 3 of Txn1 gene ( (c. 160 T > C) was delivered into embryos by electroporation. The two-cell stage embryos were transferred into the oviducts of pseudopregnant females. The rat called Txn1-F54L rat, replicates Adem rats (RGD:288084580) which carried Phe54Leu mutation in the same gene.These two strains exhibit similar phenotype.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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