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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=158013766
Proper Citation: RRID:RGD_158013766
Description: Rattus norvegicus with name SD-Akt1em1Soar from RGD.
Species: Rattus norvegicus
Notes: This Akt mutant strain was created in zygotes from Holtzman Sprague-Dawley. Guided RNAs targeting exon 4 (target sequence: GCCGTTTGAGTCCATCAGCC; nucleotides 356-375) and exon 7 (target sequence: TTGTCATGGAGTACGCCAAT; nucleotides 712-731) of the Akt1 gene (NM_033230.3) were injected to the embryos to create a1332-bp deletion from exon 4 to exon7, resulting a premature stop of the protein.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)