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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13451132
Proper Citation: RRID:RGD_13451132
Description: Rattus norvegicus with name BN-Crb1m1 from RGD.
Species: Rattus norvegicus
Notes: This Brown Norway from Janvier rat strain spontaneously develops progressive focal retinal layer disorganization, loss of photoreceptors, cystic cavitation, and RMG abnormalities associated with early retinal vascular telangiectasia and late stage subretinal neovascularization. This phenotype bears reminiscent of human Macular telangiectasia 2. A deletion insertion mutation in exon 6 of the rat crb1 was identified to be responsible for this retinal phenotype.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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