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Organism Name
SD-Tg(CAG-KRAS*G12V)301Jcl
RRID:RGD_126848778 RRID Copied  
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RRID:RGD_126848778
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Organism Information

URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=126848778

Proper Citation: RRID:RGD_126848778

Description: Rattus norvegicus with name SD-Tg(CAG-KRAS*G12V)301Jcl from RGD.

Species: Rattus norvegicus

Notes: The transgene consisting of CAG promoter/loxP/neomycin resistant gene casette/lox/Ha-Kras*G12V (KrasV12) was injected into embryos of SD rat (RGD:8547938). This strain was generated at CLEA Japan,Inc. This strain is introduced 3 copies of hemagglutinin (HA) epitope tag connected HA-K-rasv12 gene expression cassette by using Cre/loxP system for controlling term/location expression of human mutated form K-rasv12 gene (changing glycine to valine at the 12 amino acid sequence) that normally floxed rat does not express K-rasv12 gene. CLEA Japan, Inc

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Ratings and Alerts

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Data and Source Information

Source: Rat Genome Database (RGD) (RRID:SCR_006444)
Description: Database for genetic, genomic, phenotype, and disease data generated from rat research. Centralized database that collects, manages, and distributes data generated from rat genetic and genomic research and makes these data available to scientific community. Curation of mapped positions for quantitative trait loci, known mutations and other phenotypic data is provided. Facilitates investigators research efforts by providing tools to search, mine, and analyze this data. Strain reports include description of strain origin, disease, phenotype, genetics, immunology, behavior with links to related genes, QTLs, sub-strains, and strain sources.
URL: http://rgd.mcw.edu

Source Database: Rat Genome Database (RGD)