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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11565826
Proper Citation: RRID:RGD_11565826
Description: Rattus norvegicus with name F344-Ttnem1Sage from RGD.
Species: Rattus norvegicus
Notes: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Ttn into F344 embryos. The zinc-finger nuclease mediated genome editing system created a 12-bp deletion and a 2-bp insertion (TA) at 228,608-228,619 (Rnor_5.0) to introduce a stop codon in exon 303, corresponding to exon 327 in the human sequence. Duke-National University of Singapore, Singapore
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)