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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11564349
Proper Citation: RRID:RGD_11564349
Description: Rattus norvegicus with name F344-Aspaem34Kyo from RGD.
Species: Rattus norvegicus
Notes: The TALEN genome editing system was used to generate this mutant rat strain. The TALEN system caused a 16-bp deletion in the exon4 of Aspa gene, as a result created a premature stop codon in the gene. Decreased expression levels of Aspa gene and ASPA protein was observed. Histopatologically, this strain shows vacuole formation in the brain and spinal cord. National BioResource Project for the Rat in Japan
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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