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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=44044
Proper Citation: RRID:MMRRC_044044-JAX
Description: Mus musculus with name B6J.129P2-Traf6tm1Mak/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection:
Phenotype: increased bone mineral density [MP:0000062]| osteopetrosis [MP:0000067]| failure of tooth eruption [MP:0000121]| absent incisors [MP:0000125]| abnormal long bone metaphysis morphology [MP:0000133]| decreased circulating phosphate level [MP:0000198]| enlarged heart [MP:0000274]| enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| decreased body length [MP:0001258]| decreased body weight [MP:0001262]| abnormal osteoclast physiology [MP:0001541]| abnormal macrophage physiology [MP:0002451]| short femur [MP:0003109]| abnormal long bone morphology [MP:0003723]| absent molars [MP:0003931]| decreased length of long bones [MP:0004686]| abnormal osteoclast morphology [MP:0004982]| decreased bone resorption [MP:0004993]| decreased B cell proliferation [MP:0005093]| hypochromic anemia [MP:0008387]| decreased tumor necrosis factor secretion [MP:0008561]| decreased survivor rate [MP:0008770]| postnatal lethality [MP:0011086]| incomplete penetrance [MP:0011090]
Affected Gene: Traf6
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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