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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=44040
Proper Citation: RRID:MMRRC_044040-JAX
Description: Mus musculus with name B6.129P2-Rhbdf2tm1Mak/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal liver physiology [MP:0000609]| eyelids open at birth [MP:0001302]| perinatal lethality [MP:0002081]| increased susceptibility to bacterial infection [MP:0002412]| abnormal leukocyte physiology [MP:0002442]| abnormal B cell physiology [MP:0002459]| abnormal immune serum protein physiology [MP:0002723]| increased width of hypertrophic chondrocyte zone [MP:0003408]| abnormal microglial cell physiology [MP:0003691]| decreased circulating tumor necrosis factor level [MP:0008554]| decreased tumor necrosis factor secretion [MP:0008561]| failure of eyelid fusion [MP:0009264]| decreased susceptibility to infection induced morbidity/mortality [MP:0009786]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009788]| enlarged aortic valve [MP:0010591]| thick aortic valve cusps [MP:0010593]| enlarged pulmonary valve [MP:0010600]| thick pulmonary valve cusps [MP:0010605]| thick tricuspid valve cusps [MP:0010626]| enlarged tricuspid valve [MP:0010627]
Affected Gene: Rhbdf2
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)