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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43609
Proper Citation: RRID:MMRRC_043609-JAX
Description: Mus musculus with name STOCK Tbx1tm1Pa/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Developmental Biology, Endocrine Deficiency, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal ear shape [MP:0000022]| lowered ear position [MP:0000024]| abnormal malleus morphology [MP:0000029]| abnormal tympanic ring morphology [MP:0000030]| abnormal otic capsule morphology [MP:0000039]| abnormal middle ear morphology [MP:0000049]| short mandible [MP:0000088]| abnormal cranium morphology [MP:0000438]| absent parathyroid glands [MP:0000680]| abnormal thymus development [MP:0000704]| athymia [MP:0000705]| abnormal myogenesis [MP:0000729]| abnormal trigeminal nerve morphology [MP:0001065]| abnormal facial nerve morphology [MP:0001071]| abnormal vestibulocochlear nerve morphology [MP:0001072]| decreased embryo size [MP:0001698]| respiratory failure [MP:0001953]| hydrops fetalis [MP:0002192]| abnormal pharyngeal muscle morphology [MP:0002253]| abnormal cricoid cartilage morphology [MP:0002258]| abnormal thyroid cartilage morphology [MP:0002260]| abnormal laryngeal muscle morphology [MP:0002263]| abnormal semicircular canal morphology [MP:0002428]| persistent truncus arteriosis [MP:0002633]| micrognathia [MP:0002639]| abnormal pharyngeal arch artery morphology [MP:0002672]| abnormal pharyngeal arch morphology [MP:0002884]| abnormal neural crest cell migration [MP:0002950]| abnormal hyoid bone morphology [MP:0003056]| absent cochlea [MP:0003147]| abnormal facial morphology [MP:0003743]| right aortic arch [MP:0004158]| double aortic arch [MP:0004159]| absent stapes [MP:0004204]| small otic vesicle [MP:0004310]| absent inner ear vestibule [MP:0004314]| abnormal zygomatic arch morphology [MP:0004469]| fusion of basioccipital and basisphenoid bone [MP:0004572]| abnormal cervical atlas morphology [MP:0004607]| absent upper incisors [MP:0004790]| absent mandibular coronoid process [MP:0004912]| abnormal middle ear ossicle morphology [MP:0005105]| abnormal incus morphology [MP:0005106]| abnormal temporal bone morphology [MP:0005272]| absent outer ear [MP:0005579]| dilated endolymphatic duct [MP:0006012]| decreased tympanic ring size [MP:0006020]| abnormal pharyngeal pouch morphology [MP:0006031]| abnormal external auditory canal morphology [MP:0006033]| inner ear hypoplasia [MP:0006286]| abnormal third pharyngeal arch morphology [MP:0006339]| abnormal fourth pharyngeal arch morphology [MP:0006340]| absent second pharyngeal arch [MP:0006345]| abnormal fourth pharyngeal arch artery morphology [MP:0006354]| abnormal palatal shelf fusion at midline [MP:0009887]| cleft secondary palate [MP:0009890]| malleus hypoplasia [MP:0010326]| thin malleus neck [MP:0010328]| absent third pharyngeal arch [MP:0010642]| absent arcus anterior [MP:0010729]| neonatal lethality [MP:0011087]| complete penetrance [MP:0012721]| short neck [MP:0013174]| pharynx stenosis [MP:0030137]| abnormal upper incisor morphology [MP:0030535]
Affected Gene: Tbx1
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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