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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=42288
Proper Citation: RRID:MMRRC_042288-UNC
Description: Mus musculus with name STOCK Tg(CAG-His3.3Rainbow)1Dean/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Reproduction, Research Tools; Mutation Type: Transgenic ; Collection:
Phenotype: decreased hematocrit [MP:0000208]| abnormal liver physiology [MP:0000609]| spleen hypoplasia [MP:0000694]| small thymus [MP:0000706]| decreased thymocyte number [MP:0000715]| arrested T cell differentiation [MP:0001825]| stomach inflammation [MP:0001873]| abnormal T cell differentiation [MP:0002145]| abnormal double-negative T cell morphology [MP:0002407]| abnormal double-positive T cell morphology [MP:0002408]| increased susceptibility to viral infection [MP:0002418]| abnormal immunoglobulin level [MP:0002490]| abnormal pancreas physiology [MP:0002693]| abnormal cytokine secretion [MP:0003009]| rheumatoid arthritis [MP:0003561]| increased autoantibody level [MP:0003725]| abnormal thymocyte activation [MP:0003850]| increased length of allograft survival [MP:0004751]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal negative T cell selection [MP:0004918]| abnormal positive T cell selection [MP:0004919]| decreased susceptibility to parasitic infection [MP:0005026]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-positive T cell number [MP:0005092]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| periinsulitis [MP:0005580]| decreased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008079]| alpha-beta T cell number [MP:0008688]| decreased CD8-positive [MP:0008874]| alpha-beta T cell number [MP:0009763]
Affected Gene: Zp3
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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