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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37646
Proper Citation: RRID:MMRRC_037646-UCD
Description: Mus musculus with name STOCK Egfrtm1Rdk/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Dermatology, Developmental Biology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: short mandible [MP:0000088]| cleft palate [MP:0000111]| pointed snout [MP:0000448]| abnormal intestine morphology [MP:0000477]| abnormal tongue epithelium morphology [MP:0000764]| atelectasis [MP:0001177]| thick pulmonary interalveolar septum [MP:0001179]| flaky skin [MP:0001195]| thin epidermis [MP:0001218]| abnormal epidermis stratum basale morphology [MP:0001231]| abnormal epidermis stratum granulosum morphology [MP:0001239]| weight loss [MP:0001263]| decreased body size [MP:0001265]| curly vibrissae [MP:0001274]| eyelids open at birth [MP:0001302]| fused cornea and lens [MP:0001307]| cyanosis [MP:0001575]| abnormal intestinal absorption [MP:0001666]| decreased embryo size [MP:0001698]| abnormal pancreas morphology [MP:0001944]| respiratory failure [MP:0001953]| respiratory distress [MP:0001954]| abnormal hair growth [MP:0002073]| abnormal outer ear morphology [MP:0002177]| abnormal bronchus morphology [MP:0002264]| abnormal terminal bronchiole morphology [MP:0002268]| abnormal pulmonary alveolus morphology [MP:0002270]| abnormal type II pneumocyte morphology [MP:0002275]| abnormal lung interstitium morphology [MP:0002276]| increased heart rate [MP:0002626]| abnormal hair follicle development [MP:0003704]| dry skin [MP:0003853]| decreased fetal size [MP:0004200]| small pancreas [MP:0004247]| small placenta [MP:0004259]| abnormal pancreatic beta cell morphology [MP:0005217]| abnormal exocrine pancreas morphology [MP:0005220]| dilated terminal bronchiole tubes [MP:0006026]| impaired lung alveolus development [MP:0006027]| petechiae [MP:0008816]| hematoma [MP:0008817]| disorganized pancreatic islets [MP:0009254]| abnormal skin appearance [MP:0009931]| dilated respiratory conducting tubes [MP:0010856]| decreased alveolar lamellar body number [MP:0010890]| abnormal pulmonary interalveolar septum morphology [MP:0010900]| abnormal pulmonary acinus morphology [MP:0010911]| abnormal branching involved in lung morphogenesis [MP:0011024]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011108]| embryonic lethality during organogenesis [MP:0013542]| incomplete penetrance [MP:0030026]
Affected Gene: Egfr
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)