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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37633
Proper Citation: RRID:MMRRC_037633-JAX
Description: Mus musculus with name STOCK Gba1tm1Rlp Tg(SNCA*A53T)1Nbm Sncatm1Nbm Tg(SNCA*A53T)2Nbm/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: enlarged liver [MP:0000599]| reddish skin [MP:0001190]| wrinkled skin [MP:0001211]| hyperkeratosis [MP:0001242]| decreased body weight [MP:0001262]| postnatal lethality [MP:0002082]| increased liver weight [MP:0002981]| increased spleen weight [MP:0004952]| postnatal lethality [MP:0011085]| kyphosis [MP:0000160]| weakness [MP:0000746]| abnormal hippocampus morphology [MP:0000807]| abnormal spinal nerve morphology [MP:0001077]| weight loss [MP:0001263]| hypoactivity [MP:0001402]| impaired coordination [MP:0001405]| abnormal gait [MP:0001406]| short stride length [MP:0001407]| abnormal posture [MP:0001504]| abnormal digestive system physiology [MP:0001663]| abnormal reflex [MP:0001961]| abnormal motor capabilities/coordination/movement [MP:0002066]| premature death [MP:0002083]| gliosis [MP:0002183]| abnormal male preputial gland morphology [MP:0002717]| abnormal ventral spinal root morphology [MP:0003993]| neuronal intranuclear inclusions [MP:0004191]| abnormal spinal cord ventral horn morphology [MP:0005112]| abnormal axon morphology [MP:0005404]| axon degeneration [MP:0005405]| abnormal intestinal transit time [MP:0006001]| abnormal large intestinal transit time [MP:0006003]| slow postnatal weight gain [MP:0008489]| alpha-synuclein inclusion body [MP:0008493]
Affected Gene: |Gba1|Snca|||SNCA|
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No rating or validation information has been found for STOCK Gba1tm1Rlp Tg(SNCA*A53T)1Nbm Sncatm1Nbm Tg(SNCA*A53T)2Nbm/Mmjax.
No alerts have been found for STOCK Gba1tm1Rlp Tg(SNCA*A53T)1Nbm Sncatm1Nbm Tg(SNCA*A53T)2Nbm/Mmjax.
Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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