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URL: https://www.mmrrc.org/catalog/cellLineSDS.php?mmrrc_id=37556
Proper Citation: RRID:MMRRC_037556-JAX
Description: Mus musculus with name B6.Cg-Mapttm1(EGFP)Klt Zbtb20Tg(PDGFB-APPSwInd)20Lms/Mmjax ES cell line ACB006 from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Transgenic ; Collection:
Phenotype: amyloidosis [MP:0000604]| abnormal spinal cord morphology [MP:0000955]| impaired coordination [MP:0001405]| abnormal spatial learning [MP:0001463]| reduced long term potentiation [MP:0001473]| premature death [MP:0002083]| abnormal brain morphology [MP:0002152]| no abnormal phenotype detected [MP:0002169]| abnormal spleen red pulp morphology [MP:0002356]| abnormal sciatic nerve morphology [MP:0002651]| abnormal motor learning [MP:0002804]| abnormal neuron morphology [MP:0002882]| neurofibrillary tangles [MP:0003214]| tau protein deposits [MP:0004250]| abnormal renal glomerulus morphology [MP:0005325]| abnormal spleen B cell follicle morphology [MP:0008470]| increased follicular lymphoma incidence [MP:0009317]| impaired contextual conditioning behavior [MP:0009454]| impaired cued conditioning behavior [MP:0009456]| enhanced spatial learning [MP:0012306]| increased lymphoma incidence [MP:0012431]
Affected Gene: |Zbtb20||APP||Mapt|EGFP
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No rating or validation information has been found for B6.Cg-Mapttm1(EGFP)Klt Zbtb20Tg(PDGFB-APPSwInd)20Lms/Mmjax ES cell line ACB006.
No alerts have been found for B6.Cg-Mapttm1(EGFP)Klt Zbtb20Tg(PDGFB-APPSwInd)20Lms/Mmjax ES cell line ACB006.
Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)